Molecular pathways involved in the cardioprotective effects of intravenous statin administration during ischemia

Multitarget Strategies to Reduce Myocardial Ischemia/Reperfusion Injury

(2019) Sean M. Davidson et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Investigating and re-evaluating the role of GSK3beta kinase as a molecular target for cardioprotection by using novel pharmacological inhibitors

(2019) Panagiota-Efstathia Nikolaou et al.   CARDIOVASCULAR RESEARCH

Optimized Treatment of ST-Elevation Myocardial Infarction

(2019) Giampaolo Niccoli et al.   CIRCULATION RESEARCH

Intravenous Statin Administration During Ischemia Exerts Cardioprotective Effects

(2019) Guiomar Mendieta et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Guidelines for experimental models of myocardial ischemia and infarction

(2018) Merry L. Lindsey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Randomized controlled trial of remote ischaemic conditioning in ST-elevation myocardial infarction as adjuvant to primary angioplasty (RIC-STEMI)

(2018) António Gaspar et al.   BASIC RESEARCH IN CARDIOLOGY

Reflection of Cardioprotection by Remote Ischemic Perconditioning in Attenuated ST-Segment Elevation During Ongoing Coronary Occlusion in PigsNovelty and Significance

(2018) Petra Kleinbongard et al.   CIRCULATION RESEARCH

Infarct Size Reduction by Targeting Ischemic Injury

(2018) Xavier Rossello et al.   CIRCULATION RESEARCH

Effect of Loading Dose of Atorvastatin Prior to Planned Percutaneous Coronary Intervention on Major Adverse Cardiovascular Events in Acute Coronary Syndrome

(2018) Otavio Berwanger et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection

(2018) Hans Erik Bøtker et al.   BASIC RESEARCH IN CARDIOLOGY

Translation, Translation, Translation

(2018) Gerd Heusch et al.   CIRCULATION RESEARCH

2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure

(2016) Piotr Ponikowski et al.   EUROPEAN HEART JOURNAL

Targeting the molecular mechanisms of ischemic damage: Protective effects of alpha-crystallin-B

(2016) Judit Cubedo et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Impact of the Timing of Metoprolol Administration During STEMI on Infarct Size and Ventricular Function

(2016) Jose M. García-Ruiz et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Simvastatin-Induced Apoptosis in Osteosarcoma Cells: A Key Role of RhoA-AMPK/p38 MAPK Signaling in Antitumor Activity

(2016) Walied A. Kamel et al.   MOLECULAR CANCER THERAPEUTICS

Ischaemic postconditioning reduces infarct size: Systematic review and meta-analysis of randomized controlled trials

(2015) Caroline Touboul et al.   Archives of Cardiovascular Diseases

Molecular Basis of Cardioprotection: Signal Transduction in Ischemic Pre-, Post-, and Remote Conditioning

(2015) G. Heusch   CIRCULATION RESEARCH

Evolving Therapies for Myocardial Ischemia/Reperfusion Injury

(2015) Borja Ibáñez et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Cyclosporine before PCI in Patients with Acute Myocardial Infarction

(2015) Thien-Tri Cung et al.   NEW ENGLAND JOURNAL OF MEDICINE

HMG-CoA reductase inhibition prior reperfusion improves reparative fibrosis post-myocardial infarction in a preclinical experimental model

(2014) Gemma Vilahur et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Rho-Kinase Inhibition Ameliorates Metabolic Disorders through Activation of AMPK Pathway in Mice

(2014) Kazuki Noda et al.   PLoS One

Senescence and aging: the critical roles of p53

(2013) A Rufini et al.   ONCOGENE

Infiltrated cardiac lipids impair myofibroblast-induced healing of the myocardial scar post-myocardial infarction

(2012) Gemma Vilahur et al.   ATHEROSCLEROSIS

Reperfusion-triggered stress protein response in the myocardium is blocked by post-conditioning. Systems biology pathway analysis highlights the key role of the canonical aryl-hydrocarbon receptor pathway

(2012) Gemma Vilahur et al.   EUROPEAN HEART JOURNAL

AMPK functions as an adenylate charge-regulated protein kinase

(2012) Jonathan S. Oakhill et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Molecular and cellular mechanisms involved in cardiac remodeling after acute myocardial infarction

(2011) Gemma Vilahur et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Acute Effects of Statins⁎⁎Editorials published in the Journal of the American College of Cardiology reflect the views of the authors and do not necessarily represent the views of JACC or the American College of Cardiology.

(2011) Ulrich Laufs et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Myocardial Redox State Predicts In-Hospital Clinical Outcome After Cardiac Surgery

(2011) Charalambos Antoniades et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170 000 participants in 26 randomised trials

(2010)   LANCET

Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

(2010) Carol Kilkenny et al.   PLOS BIOLOGY

Induction of RISK by HMG-CoA reductase inhibition affords cardioprotection after myocardial infarction

(2009) Gemma Vilahur et al.   ATHEROSCLEROSIS

Ischemic postconditioning: experimental models and protocol algorithms

(2009) Andreas Skyschally et al.   BASIC RESEARCH IN CARDIOLOGY

Ischaemic postconditioning protects against reperfusion injury via the SAFE pathway

(2009) Lydia Lacerda et al.   CARDIOVASCULAR RESEARCH

Efficacy of Atorvastatin Reload in Patients on Chronic Statin Therapy Undergoing Percutaneous Coronary Intervention

(2009) Germano Di Sciascio et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Exogenous in vivo NO-donor treatment preserves p53 levels and protects vascular cells from apoptosis

(2008) Xavier Duran et al.   ATHEROSCLEROSIS

Short-term myocardial ischemia induces cardiac modified C-reactive protein expression and proinflammatory gene (cyclo-oxygenase-2, monocyte chemoattractant protein-1, and tissue factor) upregulation in peripheral blood mononuclear cells

(2008) G. VILAHUR et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL