Adamts5 −/− Mice Exhibit Altered Aggrecan Proteolytic Profiles That Correlate With Ascending Aortic Anomalies

ADAMTS-9 in Mouse Cartilage Has Aggrecanase Activity That Is Distinct from ADAMTS-4 and ADAMTS-5

(2019) Fraser Rogerson et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of ADAMTS-5 in Aortic Dilatation and Extracellular Matrix RemodelingHighlights

(2018) Marika Fava et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The Zonal Architecture of the Mandibular Condyle Requires ADAMTS5

(2018) A.W. Rogers et al.   JOURNAL OF DENTAL RESEARCH

Nitric oxide mediates aortic disease in mice deficient in the metalloprotease Adamts1 and in a mouse model of Marfan syndrome

(2017) Jorge Oller et al.   NATURE MEDICINE

Critical Role of ADAMTS-4 in the Development of Sporadic Aortic Aneurysm and Dissection in Mice

(2017) Pingping Ren et al.   Scientific Reports

Extracellular Matrix Proteomics Reveals Interplay of Aggrecan and Aggrecanases in Vascular Remodeling of Stented Coronary Arteries

(2017) Gonca Suna et al.   CIRCULATION

Many Faces of Matrix Metalloproteinases in Aortic Aneurysms: Figure.

(2015) Hong Lu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Investigational drugs for the treatment of osteoarthritis

(2015) Kang Wang et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Bioactivity in an Aggrecan 32-mer Fragment Is Mediated via Toll-like Receptor 2

(2015) Sophie Lees et al.   Arthritis & Rheumatology

Insufficient versican cleavage and Smad2 phosphorylation results in bicuspid aortic and pulmonary valves

(2013) Loren E. Dupuis et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

ADAMTS5 is required for biomechanically-stimulated healing of murine tendinopathy

(2013) Rebecca Bell et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Novel Role of ADAMTS-5 Protein in Proteoglycan Turnover and Lipoprotein Retention in Atherosclerosis

(2012) Athanasios Didangelos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteoglycan degradation by the ADAMTS family of proteinases

(2011) Heather Stanton et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Altered versican cleavage in ADAMTS5 deficient mice; A novel etiology of myxomatous valve disease

(2011) Loren E. Dupuis et al.   DEVELOPMENTAL BIOLOGY

Regulation of matrix metalloproteinase activity in health and disease

(2010) Elin Hadler-Olsen et al.   FEBS Journal

Reduced versican cleavage due to Adamts9 haploinsufficiency is associated with cardiac and aortic anomalies

(2010) Christine B. Kern et al.   MATRIX BIOLOGY

Epidemiology of thoracic aortic dissection

(2010) Scott A. LeMaire et al.   Nature Reviews Cardiology

ADAMTS Metalloproteases Generate Active Versican Fragments that Regulate Interdigital Web Regression

(2009) Daniel R. McCulloch et al.   DEVELOPMENTAL CELL

A Disintegrin-like and Metalloprotease (Reprolysin-type) with Thrombospondin Type 1 Motif (ADAMTS) Superfamily: Functions and Mechanisms

(2009) Suneel S. Apte   JOURNAL OF BIOLOGICAL CHEMISTRY

Arterial remodeling in vascular disease: a key role for hyaluronan and versican

(2008) Thomas et al.   Frontiers in Bioscience-Landmark