Anti-inflammatory effects of melatonin in multiple sclerosis

Melatonin enhances interleukin-10 expression and suppresses chemotaxis to inhibit inflammation in situ and reduce the severity of experimental autoimmune encephalomyelitis

(2016) Shyi-Jou Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Prevalence of Comorbidities, Overweight and Obesity in an International Sample of People with Multiple Sclerosis and Associations with Modifiable Lifestyle Factors

(2016) Claudia Helena Marck et al.   PLoS One

Decreased Daily Melatonin Levels in Women with Systemic Lupus Erythematosus - A Short Report

(2016) Ralitsa Robeva et al.   Balkan Medical Journal

Clinical and pathological insights into the dynamic nature of the white matter multiple sclerosis plaque

(2015) Josa M. Frischer et al.   ANNALS OF NEUROLOGY

Melatonin controls experimental autoimmune encephalomyelitis by altering the T effector/regulatory balance

(2015) Nuria Álvarez-Sánchez et al.   BRAIN BEHAVIOR AND IMMUNITY

Melatonin Contributes to the Seasonality of Multiple Sclerosis Relapses

(2015) Mauricio F. Farez et al.   CELL

Melatonin treatment improves primary progressive multiple sclerosis: a case report

(2015) Antonio López-González et al.   JOURNAL OF PINEAL RESEARCH

Shift work influences multiple sclerosis risk

(2015) AK Hedström et al.   Multiple Sclerosis Journal

Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-α

(2015) Ivan D Mascanfroni et al.   NATURE MEDICINE

Shift work influences multiple sclerosis risk

(2015) AK Hedström et al.   Multiple Sclerosis Journal

Seasonal variation of relapse rate in multiple sclerosis is latitude dependent

(2014) Tim Spelman et al.   ANNALS OF NEUROLOGY

Immunology of Relapse and Remission in Multiple Sclerosis

(2014) Lawrence Steinman   Annual Review of Immunology

Seasonal vitamin D changes and the impact on health risk assessment

(2014) Robert Rosecrans et al.   CLINICAL BIOCHEMISTRY

Melatonin Attenuates Dextran Sodium Sulfate Induced Colitis with Sleep Deprivation: Possible Mechanism by Microarray Analysis

(2014) Sook Hee Chung et al.   DIGESTIVE DISEASES AND SCIENCES

Elevated melatonin levels in natalizumab-treated female patients with relapsing-remitting multiple sclerosis: Relationship to oxidative stress

(2014) Carmen Bahamonde et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

RORα and ROR γ are expressed in human skin and serve as receptors for endogenously produced noncalcemic 20-hydroxy- and 20,23-dihydroxyvitamin D

(2014) Andrzej T. Slominski et al.   FASEB JOURNAL

Sodium intake is associated with increased disease activity in multiple sclerosis

(2014) Mauricio F Farez et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Multiple sclerosis genetics

(2014) Stephen Sawcer et al.   LANCET NEUROLOGY

Multiple Sclerosis: Current and Emerging Disease-Modifying Therapies and Treatment Strategies

(2014) Dean M. Wingerchuk et al.   MAYO CLINIC PROCEEDINGS

Vitamin D as an Early Predictor of Multiple Sclerosis Activity and Progression

(2014) Alberto Ascherio et al.   JAMA Neurology

Melatonin Reduces Ulcerative Colitis-Associated Local and Systemic Damage in Mice: Investigation on Possible Mechanisms

(2013) P. P. Trivedi et al.   DIGESTIVE DISEASES AND SCIENCES

Melatonin: Buffering the Immune System

(2013) Antonio Carrillo-Vico et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

(2013) Ashley H Beecham et al.   NATURE GENETICS

IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39

(2013) Ivan D Mascanfroni et al.   NATURE IMMUNOLOGY

How Cytokine Networks Fuel Inflammation: Interleukin-17 and a tale of two autoimmune diseases

(2013) Dominique L. P. Baeten et al.   NATURE MEDICINE

TH17 Cell Differentiation Is Regulated by the Circadian Clock

(2013) X. Yu et al.   SCIENCE

Melatonin pathway genes are associated with progressive subtypes and disability status in multiple sclerosis among Finnish patients

(2012) Renuka Natarajan et al.   JOURNAL OF NEUROIMMUNOLOGY

Oligoclonal bands and cerebrospinal fluid markers in multiple sclerosis: associations with disease course and progression

(2012) Pedro Lourenco et al.   Multiple Sclerosis Journal

The epidemiology of multiple sclerosis in Latin America and the Caribbean: a systematic review

(2012) E Cristiano et al.   Multiple Sclerosis Journal

Vitamin D and disease activity in multiple sclerosis before and during interferon-  treatment

(2012) K. I. Loken-Amsrud et al.   NEUROLOGY

Lower serum vitamin D levels are associated with a higher relapse risk in multiple sclerosis

(2012) T. F. Runia et al.   NEUROLOGY

Shift work at young age is associated with increased risk for multiple sclerosis

(2011) Anna Karin Hedström et al.   ANNALS OF NEUROLOGY

Melatonin synthesized by T lymphocytes as a ligand of the retinoic acid-related orphan receptor

(2011) Patricia J. Lardone et al.   JOURNAL OF PINEAL RESEARCH

Melatonin enhances endogenous heme oxygenase-1 and represses immune responses to ameliorate experimental murine membranous nephropathy

(2011) Chia-Chao Wu et al.   JOURNAL OF PINEAL RESEARCH

Melatonin dysregulation, sleep disturbances and fatigue in multiple sclerosis

(2011) Lena Melamud et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

(2011) Stephen Sawcer et al.   NATURE

Systemic Lupus Erythematosus

(2011) George C. Tsokos   NEW ENGLAND JOURNAL OF MEDICINE

In Vivo Induction of Tr1 Cells via Mucosal Dendritic Cells and AHR Signaling

(2011) Henry Yim Wu et al.   PLoS One

Type 1 regulatory T cells (Tr1) in autoimmunity

(2011) Caroline Pot et al.   SEMINARS IN IMMUNOLOGY

Distribution, function and physiological role of melatonin in the lower gut

(2011) Chun-Qiu Chen   WORLD JOURNAL OF GASTROENTEROLOGY

Pinealectomy ameliorates collagen II-induced arthritis in mice

(2010) I. HANSSON et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The ‘hygiene hypothesis’ for autoimmune and allergic diseases: an update

(2010) H. Okada et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Melatonin Expresses Powerful Anti-inflammatory and Antioxidant Activities Resulting in Complete Improvement of Acetic-Acid-Induced Colitis in Rats

(2010) Gulgun Tahan et al.   DIGESTIVE DISEASES AND SCIENCES

Regulatory Effect of Melatonin on Cytokine Disturbances in the Pristane-Induced Lupus Mice

(2010) Ling-ling Zhou et al.   MEDIATORS OF INFLAMMATION

The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27

(2010) Lionel Apetoh et al.   NATURE IMMUNOLOGY

Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell–like and Foxp3+ regulatory T cells

(2010) Roopali Gandhi et al.   NATURE IMMUNOLOGY

Melatonin attenuates clock gene Cryptochrome1, which may aggravates mouse anti-type II collagen antibody-induced arthritis

(2010) Jihye Bang et al.   RHEUMATOLOGY INTERNATIONAL

Immunomodulatory effects of Vitamin D in multiple sclerosis

(2009) J. Correale et al.   BRAIN

Melatonin prolongs islet graft survival in diabetic NOD mice

(2009) Gu-Jiun Lin et al.   JOURNAL OF PINEAL RESEARCH

Association of disease-predisposition polymorphisms of the melatonin receptors and sunshine duration in the global human populations

(2009) Lin-dan Ji et al.   JOURNAL OF PINEAL RESEARCH

Inflammatory Bowel Disease

(2009) Clara Abraham et al.   NEW ENGLAND JOURNAL OF MEDICINE

Interleukin-17 and Type 17 Helper T Cells

(2009) Pierre Miossec et al.   NEW ENGLAND JOURNAL OF MEDICINE

Transcriptional Activation of HIF-1 by RORα and its Role in Hypoxia Signaling

(2008) Eun-Jin Kim et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Melatonin treatment does not improve rheumatoid arthritis

(2008) Georges J. Maestroni et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Melatonin receptors, heterodimerization, signal transduction and binding sites: what's new?

(2008) R Jockers et al.   BRITISH JOURNAL OF PHARMACOLOGY

A novel interplay between membrane and nuclear melatonin receptors in human lymphocytes: significance in IL-2 production

(2008) P. J. Lardone et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Treatment with testosterone or estradiol in melatonin treated females and males MRL/MpJ-Faslprmice induces negative effects in developing systemic lupus erythematosus

(2008) Antonio J. Jimenez-Caliani et al.   JOURNAL OF PINEAL RESEARCH

Melatonin usage in ulcerative colitis: a case report

(2008) M. D. Maldonado et al.   JOURNAL OF PINEAL RESEARCH

Melatonin receptor antagonist luzindole is a powerful radical scavenger in vitro

(2008) Alexander M. Mathes et al.   JOURNAL OF PINEAL RESEARCH

Matrix metalloproteinase-9 and metalloproteinase-2 activity and expression is reduced by melatonin during experimental colitis

(2008) Emanuela Esposito et al.   JOURNAL OF PINEAL RESEARCH

Multiple sclerosis

(2008) Alastair Compston et al.   LANCET

Environmental factors and multiple sclerosis

(2008) George C Ebers   LANCET NEUROLOGY

Immunomodulation by Melatonin: Its Significance for Seasonally Occurring Diseases

(2008) Venkataramanujam Srinivasan et al.   NEUROIMMUNOMODULATION

Physiological effects of melatonin: Role of melatonin receptors and signal transduction pathways

(2008) S PANDIPERUMAL et al.   PROGRESS IN NEUROBIOLOGY

The association of nocturnal serum melatonin levels with major depression in patients with acute multiple sclerosis

(2008) Zehra Akpınar et al.   PSYCHIATRY RESEARCH

Elevated Activity and Microglial Expression of Myeloperoxidase in Demyelinated Cerebral Cortex in Multiple Sclerosis

(2007) Elizabeth Gray et al.   BRAIN PATHOLOGY