Development of Neutropenic Murine Models of Iron Overload and Depletion To Study the Efficacy of Siderophore-Antibiotic Conjugates

Siderophore–antibiotic conjugates: exploiting iron uptake to deliver drugs into bacteria

(2018) I.J. Schalk   CLINICAL MICROBIOLOGY AND INFECTION

Humanized Exposures of Cefiderocol, a Siderophore Cephalosporin, Display Sustained in vivo Activity against Siderophore-Resistant Pseudomonas aeruginosa

(2018) Islam M. Ghazi et al.   PHARMACOLOGY

Pathophysiology and classification of iron overload diseases; update 2018

(2018) Pierre Brissot et al.   TRANSFUSION CLINIQUE ET BIOLOGIQUE

Efficacy of Humanized Cefiderocol Exposures Over 72 hours Against a Diverse Group of Gram-Negative Isolates in the Neutropenic Murine Thigh Infection Model

(2018) Sean M Stainton et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Siderophore Cephalosporin Cefiderocol Utilizes Ferric Iron Transporter Systems for Antibacterial Activity againstPseudomonas aeruginosa

(2016) Akinobu Ito et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Iron deficiency anaemia

(2016) Anthony Lopez et al.   LANCET

Pharmacodynamic Profiling of a Siderophore-Conjugated Monocarbam in Pseudomonas aeruginosa: Assessing the Risk for Resistance and Attenuated Efficacy

(2015) Aryun Kim et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Siderophore-dependent iron uptake systems as gates for antibiotic Trojan horse strategies against Pseudomonas aeruginosa

(2014) Gaëtan L. A. Mislin et al.   Metallomics

Adaptation-Based Resistance to Siderophore-Conjugated Antibacterial Agents by Pseudomonas aeruginosa

(2013) Andrew P. Tomaras et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Iron in Infection and Immunity

(2013) James E. Cassat et al.   Cell Host & Microbe

Mineral Malnutrition Following Bariatric Surgery

(2013) Nana Gletsu-Miller et al.   Advances in Nutrition

Hepcidin and iron homeostasis

(2012) Tomas Ganz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Iron Overload in Human Disease

(2012) Robert E. Fleming et al.   NEW ENGLAND JOURNAL OF MEDICINE

Knockout Mouse Models of Iron Homeostasis

(2011) Robert E. Fleming et al.   Annual Review of Nutrition

Iron-Chelating Therapy for Transfusional Iron Overload

(2011) Gary M. Brittenham   NEW ENGLAND JOURNAL OF MEDICINE

Iron Homeostasis and the Inflammatory Response

(2010) Marianne Wessling-Resnick   Annual Review of Nutrition

The iron chelator, desferrioxamine, reduces inflammation and atherosclerotic lesion development in experimental mice

(2010) Wei-Jian Zhang et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Animal Models of Anemia of Inflammation

(2009) Seth Rivera et al.   SEMINARS IN HEMATOLOGY

Iron Depletion by Deferoxamine Up-Regulates Glucose Uptake and Insulin Signaling in Hepatoma Cells and in Rat Liver

(2008) Paola Dongiovanni et al.   AMERICAN JOURNAL OF PATHOLOGY