Tropomyosin receptor kinase (TRK) biology and the role of NTRK gene fusions in cancer
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Title
Tropomyosin receptor kinase (TRK) biology and the role of NTRK gene fusions in cancer
Authors
Keywords
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Journal
ANNALS OF ONCOLOGY
Volume 30, Issue Supplement_8, Pages viii5-viii15
Publisher
Oxford University Press (OUP)
Online
2019-09-05
DOI
10.1093/annonc/mdz383
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Note: Only part of the references are listed.- Larotrectinib in adult patients with solid tumours: a multicentre, open-label, phase I dose-escalation study
- (2019) D S Hong et al. ANNALS OF ONCOLOGY
- NTRK fusion detection across multiple assays and 33,997 cases: diagnostic implications and pitfalls
- (2019) James P. Solomon et al. MODERN PATHOLOGY
- Molecularly defined diffuse leptomeningeal glioneuronal tumor (DLGNT) comprises two subgroups with distinct clinical and genetic features
- (2018) Maximilian Y. Deng et al. ACTA NEUROPATHOLOGICA
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- (2018) Cecilia Lezcano et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- NTRK Fusions Define a Novel Uterine Sarcoma Subtype With Features of Fibrosarcoma
- (2018) Sarah Chiang et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- TRKA expression andNTRK1gene copy number across solid tumours
- (2018) Gianluca Mauri et al. JOURNAL OF CLINICAL PATHOLOGY
- Efficacy of Larotrectinib in TRK Fusion–Positive Cancers in Adults and Children
- (2018) Alexander Drilon et al. NEW ENGLAND JOURNAL OF MEDICINE
- Actionable fusions in colorectal cancer using a cell-free circulating tumor DNA (ctDNA) assay.
- (2018) Katherine Clifton et al. JOURNAL OF CLINICAL ONCOLOGY
- NTRK fusion-positive cancers and TRK inhibitor therapy
- (2018) Emiliano Cocco et al. Nature Reviews Clinical Oncology
- TRK Inhibition: A New Tumor-Agnostic Treatment Strategy
- (2018) Shivaani Kummar et al. Targeted Oncology
- Analysis of Clinical Features of Mammary Analog Secretory Carcinoma Using the Surveillance, Epidemiology, and End Results Database
- (2018) Jennifer L. Anderson et al. JAMA Otolaryngology-Head & Neck Surgery
- ALK, ROS1, and NTRK Rearrangements in Metastatic Colorectal Cancer
- (2017) Filippo Pietrantonio et al. JNCI-Journal of the National Cancer Institute
- Activity of Entrectinib in a Patient With the First Reported NTRK Fusion in Neuroendocrine Cancer
- (2017) Darren Sigal et al. Journal of the National Comprehensive Cancer Network
- Recurrent EML4–NTRK3 fusions in infantile fibrosarcoma and congenital mesoblastic nephroma suggest a revised testing strategy
- (2017) Alanna J Church et al. MODERN PATHOLOGY
- Fusions in solid tumours: diagnostic strategies, targeted therapy, and acquired resistance
- (2017) Alison M. Schram et al. Nature Reviews Clinical Oncology
- Identification of NTRK fusions in pediatric mesenchymal tumors
- (2017) Dean Pavlick et al. PEDIATRIC BLOOD & CANCER
- Somatic chromosomal engineering identifies BCAN-NTRK1 as a potent glioma driver and therapeutic target
- (2017) Peter J. Cook et al. Nature Communications
- Safety and Antitumor Activity of the Multitargeted Pan-TRK, ROS1, and ALK Inhibitor Entrectinib: Combined Results from Two Phase I Trials (ALKA-372-001 and STARTRK-1)
- (2017) Alexander Drilon et al. Cancer Discovery
- A Next-Generation TRK Kinase Inhibitor Overcomes Acquired Resistance to Prior TRK Kinase Inhibition in Patients with TRK Fusion–Positive Solid Tumors
- (2017) Alexander Drilon et al. Cancer Discovery
- Identification and characterization of a novel SCYL3-NTRK1 rearrangement in a colorectal cancer patient
- (2017) Massimo Milione et al. Oncotarget
- BRCA2, EGFR, and NTRK mutations in mismatch repair-deficient colorectal cancers with MSH2 or MLH1 mutations
- (2017) Safoora Deihimi et al. Oncotarget
- ALK, ROS1, and NTRK Rearrangements in Metastatic Colorectal Cancer
- (2017) Filippo Pietrantonio et al. JNCI-Journal of the National Cancer Institute
- Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology
- (2016) Ibrahim Qaddoumi et al. ACTA NEUROPATHOLOGICA
- ETV6-NTRK3 Is Expressed in a Subset of ALK-Negative Inflammatory Myofibroblastic Tumors
- (2016) Ali H. Alassiri et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- Recurrent NTRK1 Gene Fusions Define a Novel Subset of Locally Aggressive Lipofibromatosis-like Neural Tumors
- (2016) Narasimhan P. Agaram et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- ALK,ROS1andNTRK3gene rearrangements in inflammatory myofibroblastic tumours
- (2016) Hidetaka Yamamoto et al. HISTOPATHOLOGY
- Genomic profiling and efficacy of anti-EGFR therapy in appendiceal adenocarcinoma.
- (2016) Maria Ignez Freitas Melro Braghiroli et al. JOURNAL OF CLINICAL ONCOLOGY
- NTRK3 kinase fusions in Spitz tumours
- (2016) Iwei Yeh et al. JOURNAL OF PATHOLOGY
- Paediatric and adult soft tissue sarcomas withNTRK1gene fusions: a subset of spindle cell sarcomas unified by a prominent myopericytic/haemangiopericytic pattern
- (2016) Florian Haller et al. JOURNAL OF PATHOLOGY
- Transcriptome sequencing identifiesETV6-NTRK3as a gene fusion involved in GIST
- (2016) Monica Brenca et al. JOURNAL OF PATHOLOGY
- FGFR1 and NTRK3 actionable alterations in “Wild-Type” gastrointestinal stromal tumors
- (2016) Eileen Shi et al. Journal of Translational Medicine
- Broad Detection of Alterations Predicted to Confer Lack of Benefit From EGFR Antibodies or Sensitivity to Targeted Therapy in Advanced Colorectal Cancer
- (2016) Andrew Rankin et al. ONCOLOGIST
- Chromosomal rearrangements involving the NTRK1 gene in colorectal carcinoma
- (2015) Laurent Créancier et al. CANCER LETTERS
- Recurrent fusion transcripts detected by whole-transcriptome sequencing of 120 primary breast cancer samples
- (2015) Jisun Kim et al. GENES CHROMOSOMES & CANCER
- Evaluation of a Congenital Infantile Fibrosarcoma by Comprehensive Genomic Profiling Reveals an LMNA-NTRK1 Gene Fusion Responsive to Crizotinib
- (2015) Victor Wong et al. JNCI-Journal of the National Cancer Institute
- Sensitivity to Entrectinib Associated With a Novel LMNA-NTRK1 Gene Fusion in Metastatic Colorectal Cancer
- (2015) Andrea Sartore-Bianchi et al. JNCI-Journal of the National Cancer Institute
- Durable Clinical Response to Entrectinib in NTRK1-Rearranged Non-Small Cell Lung Cancer
- (2015) Anna F. Farago et al. Journal of Thoracic Oncology
- Activating MET kinase rearrangements in melanoma and Spitz tumours
- (2015) Iwei Yeh et al. Nature Communications
- The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets
- (2015) Enzo Medico et al. Nature Communications
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- (2015) M. Russo et al. Cancer Discovery
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- (2015) R. C. Doebele et al. Cancer Discovery
- NTRK1 rearrangement in colorectal cancer patients: evidence for actionable target using patient-derived tumor cell line
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- (2015) Victor Wong et al. JNCI-Journal of the National Cancer Institute
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- (2015) Andrea Sartore-Bianchi et al. JNCI-Journal of the National Cancer Institute
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- (2015) Kathryn G. Roberts et al. NEW ENGLAND JOURNAL OF MEDICINE
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- The TPM3-NTRK1 rearrangement is a recurring event in colorectal carcinoma and is associated with tumor sensitivity to TRKA kinase inhibition
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- (2014) J. S. Ross et al. ONCOLOGIST
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- (2014) Nicolas Stransky et al. Nature Communications
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- (2014) Thomas Wiesner et al. Nature Communications
- TRKing Down an Old Oncogene in a New Era of Targeted Therapy
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- (2013) Rebecca J. Leeman-Neill et al. CANCER
- Identification of kinase fusion oncogenes in post-Chernobyl radiation-induced thyroid cancers
- (2013) Julio C. Ricarte-Filho et al. JOURNAL OF CLINICAL INVESTIGATION
- The integrated landscape of driver genomic alterations in glioblastoma
- (2013) Veronique Frattini et al. NATURE GENETICS
- Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
- (2013) David T W Jones et al. NATURE GENETICS
- Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer
- (2013) Aria Vaishnavi et al. NATURE MEDICINE
- Non-Small Cell Lung Cancer: Epidemiology, Risk Factors, Treatment, and Survivorship
- (2012) Julian R. Molina et al. MAYO CLINIC PROCEEDINGS
- Mammary Analogue Secretory Carcinoma of Salivary Glands, Containing the ETV6-NTRK3 Fusion Gene: A Hitherto Undescribed Salivary Gland Tumor Entity
- (2010) Alena Skálová et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- The Biology of Neurotrophins, Signalling Pathways, and Functional Peptide Mimetics of Neurotrophins and their Receptors
- (2008) Stephen Skaper CNS & Neurological Disorders-Drug Targets
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