“Direct” 13 C Hyperpolarization of 13 C-Acetate by MicroTesla NMR Signal Amplification by Reversible Exchange (SABRE)

Hyperpolarizing Pyruvate via Signal Amplification By Reversible Exchange (SABRE)

(2019) Simon Duckett et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Quasi-Resonance Fluorine-19 Signal Amplification by Reversible Exchange

(2019) Nuwandi M. Ariyasingha et al.   Journal of Physical Chemistry Letters

Parahydrogen-based Hyperpolarization for Biomedicine

(2018) Jan Hovener et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Toward Cleavable Metabolic/pH Sensing “Double Agents” Hyperpolarized by NMR Signal Amplification by Reversible Exchange

(2018) Bryce E. Kidd et al.   CHEMISTRY-A EUROPEAN JOURNAL

Hyperpolarized NMR Spectroscopy: d -DNP, PHIP, and SABRE Techniques

(2018) Kirill V. Kovtunov et al.   Chemistry-An Asian Journal

Achieving Biocompatible SABRE: An in vitro Cytotoxicity Study

(2018) Anand Manoharan et al.   ChemMedChem

Facile Removal of Homogeneous SABRE Catalysts for Purifying Hyperpolarized Metronidazole, a Potential Hypoxia Sensor

(2018) Bryce E. Kidd et al.   Journal of Physical Chemistry C

SABRE-Relay: A Versatile Route to Hyperpolarization

(2018) Soumya S. Roy et al.   Journal of Physical Chemistry Letters

Rapid Catalyst Capture Enables Metal-Free para-Hydrogen-Based Hyperpolarized Contrast Agents

(2018) Danila A. Barskiy et al.   Journal of Physical Chemistry Letters

The 13C hyperpolarized pyruvate generated by ParaHydrogen detects the response of the heart to altered metabolism in real time

(2018) Eleonora Cavallari et al.   Scientific Reports

Using para hydrogen to hyperpolarize amines, amides, carboxylic acids, alcohols, phosphates, and carbonates

(2018) Wissam Iali et al.   Science Advances

Hyperpolarized 13C MRI: Path to Clinical Translation in Oncology

(2018) John Kurhanewicz et al.   NEOPLASIA

High-resolution hyperpolarized in vivo metabolic 13 C spectroscopy at low magnetic field (48.7 mT) following murine tail-vein injection

(2017) Aaron M. Coffey et al.   JOURNAL OF MAGNETIC RESONANCE

Generalizing, Extending, and Maximizing Nitrogen-15 Hyperpolarization Induced by Parahydrogen in Reversible Exchange

(2017) Johannes F. P. Colell et al.   Journal of Physical Chemistry C

Spin Relays Enable Efficient Long-Range Heteronuclear Signal Amplification by Reversible Exchange

(2017) Roman V. Shchepin et al.   Journal of Physical Chemistry C

Long-Lived 13C2 Nuclear Spin States Hyperpolarized by Parahydrogen in Reversible Exchange at Microtesla Fields

(2017) Zijian Zhou et al.   Journal of Physical Chemistry Letters

Direct Hyperpolarization of Nitrogen-15 in Aqueous Media with Parahydrogen in Reversible Exchange

(2017) Johannes F. P. Colell et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hyperpolarized [1-13C]-acetate Renal Metabolic Clearance Rate Mapping

(2017) Emmeli F. R. Mikkelsen et al.   Scientific Reports

Open-Source Automated Parahydrogen Hyperpolarizer for Molecular Imaging Using 13C Metabolic Contrast Agents

(2016) Aaron M. Coffey et al.   ANALYTICAL CHEMISTRY

A New Ir-NHC Catalyst for Signal Amplification by Reversible Exchange in D2O

(2016) Peter Spannring et al.   CHEMISTRY-A EUROPEAN JOURNAL

Aqueous NMR Signal Enhancement by Reversible Exchange in a Single Step Using Water-Soluble Catalysts

(2016) Fan Shi et al.   Journal of Physical Chemistry C

NMR Signal Amplification by Reversible Exchange of Sulfur-Heterocyclic Compounds Found In Petroleum

(2016) Roman V. Shchepin et al.   ChemistrySelect

Facing and Overcoming Sensitivity Challenges in Biomolecular NMR Spectroscopy

(2015) Jan-Henrik Ardenkjaer-Larsen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

15N Hyperpolarization by Reversible Exchange Using SABRE-SHEATH

(2015) Milton L. Truong et al.   Journal of Physical Chemistry C

Nanoscale Catalysts for NMR Signal Enhancement by Reversible Exchange

(2015) Fan Shi et al.   Journal of Physical Chemistry C

Microtesla SABRE Enables 10% Nitrogen-15 Nuclear Spin Polarization

(2015) Thomas Theis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Imaging Metabolism with Hyperpolarized 13C-Labeled Cell Substrates

(2015) Kevin M. Brindle   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

ParaHydrogen Induced Polarization of 13C carboxylate resonance in acetate and pyruvate

(2015) Francesca Reineri et al.   Nature Communications

Production of Catalyst-Free Hyperpolarised Ethanol Aqueous Solution via Heterogeneous Hydrogenation with Parahydrogen

(2015) Oleg G. Salnikov et al.   Scientific Reports

Analysis of Cancer Metabolism by Imaging Hyperpolarized Nuclei: Prospects for Translation to Clinical Research

(2015) John Kurhanewicz et al.   NEOPLASIA

Heterogeneous Solution NMR Signal Amplification by Reversible Exchange

(2014) Fan Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hyperpolarized Magnetic Resonance as a Sensitive Detector of Metabolic Function

(2014) Arnaud Comment et al.   BIOCHEMISTRY

Acetate Is a Bioenergetic Substrate for Human Glioblastoma and Brain Metastases

(2014) Tomoyuki Mashimo et al.   CELL

NMR Hyperpolarization Techniques for Biomedicine

(2014) Panayiotis Nikolaou et al.   CHEMISTRY-A EUROPEAN JOURNAL

Noninvasive In Vivo Imaging of Diabetes-Induced Renal Oxidative Stress and Response to Therapy Using Hyperpolarized13C Dehydroascorbate Magnetic Resonance

(2014) Kayvan R. Keshari et al.   DIABETES

Irreversible Catalyst Activation Enables Hyperpolarization and Water Solubility for NMR Signal Amplification by Reversible Exchange

(2014) Milton L. Truong et al.   JOURNAL OF PHYSICAL CHEMISTRY B

In vivo enzymatic activity of acetylCoA synthetase in skeletal muscle revealed by 13C turnover from hyperpolarized [1-13C]acetate to [1-13C]acetylcarnitine

(2013) Jessica A.M. Bastiaansen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Metabolic Imaging of Patients with Prostate Cancer Using Hyperpolarized [1-13C]Pyruvate

(2013) S. J. Nelson et al.   Science Translational Medicine

In Vivo Detection of Brain Krebs Cycle Intermediate by Hyperpolarized Magnetic Resonance

(2012) Mor Mishkovsky et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Use of Labile Precursors for the Generation of Hyperpolarized Molecules from Hydrogenation with Parahydrogen and Aqueous-Phase Extraction

(2011) Francesca Reineri et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Iridium N-Heterocyclic Carbene Complexes as Efficient Catalysts for Magnetization Transfer frompara-Hydrogen

(2011) Michael J. Cowley et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Real-Time Molecular Imaging of Tricarboxylic Acid Cycle Metabolism in Vivo by Hyperpolarized 1-13C Diethyl Succinate

(2011) Niki M. Zacharias et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Parahydrogen-induced polarization (PHIP) hyperpolarized MR receptor imaging in vivo: a pilot study of 13C imaging of atheroma in mice

(2011) Pratip Bhattacharya et al.   NMR IN BIOMEDICINE

Swift Acetate Glial Assay (SAGA): An accelerated human 13C MRS brain exam for clinical diagnostic use

(2010) Napapon Sailasuta et al.   JOURNAL OF MAGNETIC RESONANCE

Metabolic imaging in the anesthetized rat brain using hyperpolarized [1-13C] pyruvate and [1-13C] ethyl pyruvate

(2010) Ralph E. Hurd et al.   MAGNETIC RESONANCE IN MEDICINE

Hyperpolarized [2-13C]-Fructose: A Hemiketal DNP Substrate for In Vivo Metabolic Imaging

(2009) Kayvan R. Keshari et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Imaging considerations for in vivo13C metabolic mapping using hyperpolarized13C-pyruvate

(2009) Y-F. Yen et al.   MAGNETIC RESONANCE IN MEDICINE

Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a marker of cell necrosis and treatment response in tumors

(2009) F. A. Gallagher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biomedical applications of hyperpolarized 13C magnetic resonance imaging

(2009) F.A. Gallagher et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Reversible Interactions with para-Hydrogen Enhance NMR Sensitivity by Polarization Transfer

(2009) R. W. Adams et al.   SCIENCE

Hyperpolarized 13C Lactate, Pyruvate, and Alanine: Noninvasive Biomarkers for Prostate Cancer Detection and Grading

(2008) M. J. Albers et al.   CANCER RESEARCH

Current and Potential Applications of Clinical 13C MR Spectroscopy

(2008) J. Kurhanewicz et al.   JOURNAL OF NUCLEAR MEDICINE

Feasibility of using hyperpolarized [1-13C]lactate as a substrate for in vivo metabolic 13C MRSI studies

(2008) Albert P. Chen et al.   MAGNETIC RESONANCE IMAGING

Quality assurance of PASADENA hyperpolarization for 13C biomolecules

(2008) Jan-Bernd Hövener et al.   MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE

Magnetic resonance imaging of pH in vivo using hyperpolarized 13C-labelled bicarbonate

(2008) Ferdia A. Gallagher et al.   NATURE