Article
Immunology
Ahreum Song, Jieun Jang, Ayeong Lee, Seo Yeon Min, Sang Gyun Lee, Soo-Chan Kim, Jaeyong Shin, Jong Hoon Kim
Summary: The study found that the reimbursement policy for rituximab in South Korea decreased the time to initiate treatment and the corticosteroid use for pemphigus patients. Additionally, the frequency of circulating desmoglein-specific atypical memory B cells can serve as a surrogate marker for a good prognosis after rituximab therapy.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Medicine, General & Internal
Ana Moya, Dimitri Buytaert, Monika Beles, Pasquale Paolisso, Juergen Duchenne, Greet Huygh, Ciska Langmans, Adelheid Roelstraete, Sofie Verstreken, Marc Goethals, Riet Dierckx, Jozef Bartunek, Martin Penicka, Guy Van Camp, Ward A. A. Heggermont, Marc Vanderheyden
Summary: This study aims to describe the temporal changes and longitudinal trajectories of Myocardial Work (MW) indices during cardiotoxic treatment. MW indices were calculated through pressure-strain loop (PSL) analysis. Results showed that prior to chemotherapy, MWI, MWE, and CW were significantly lower in patients with moderate Cancer Therapeutics-Related Cardiac Dysfunction (CTRCDmod) than in patients without CTRCD (CTRCDneg) and with mild CTRCD (CTRCDmild). At 6 months, overt cardiac dysfunction in CTRCDmod was accompanied by worse values in MWI, MWE, and WW compared to CTRCDneg and CTRCDmild. MW features such as low baseline CW and a rise in WW at follow-up may indicate risk for CTRCD.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Endocrinology & Metabolism
Rong Huang, Jiewen Jin, Pengyuan Zhang, Kemin Yan, Hanrong Zhang, Xin Chen, Wei He, Hongyu Guan, Zhihong Liao, Haipeng Xiao, Yanbing Li, Hai Li
Summary: Cardiovascular disease has become a major concern for individuals with acromegaly, and identifying cardiac dysfunction early is crucial. Speckle tracking echocardiography has proven to be an effective method for assessing myocardial function and detecting subclinical and clinical abnormalities. This technique offers valuable insights for risk stratification and prognosis, aiding in the timely intervention and optimal treatment for acromegaly patients with concomitant cardiovascular disease.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Fuwei Jia, Xiao Li, Dingding Zhang, Shu Jiang, Jie Yin, Xiaojin Feng, Yanlin Zhu, Yingxian Liu, Yuanyuan Zhu, Jinzhi Lai, Huaxia Yang, Ligang Fang, Wei Chen, Yining Wang
Summary: This study evaluated the association between myocardial strain and fibrosis in AIDs patients, finding that impaired GLS was related to the presence and extent of myocardial fibrosis, and provided incremental prognostic value in addition to LGE for predicting adverse outcomes.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Rheumatology
Eleni Frangou, Panagiotis Garantziotis, Maria Grigoriou, Aggelos Banos, Dionysis Nikolopoulos, Antigone Pieta, Stavros A. Doumas, Antonis Fanouriakis, Aikaterini Hatzioannou, Theodora Manolakou, Themis Alissafi, Panayotis Verginis, Emmanouil Athanasiadis, Emmanouil Dermitzakis, George Bertsias, Anastasia Filia, Dimitrios T. Boumpas
Summary: By using RNA sequencing in mouse models and human datasets, we identified kidney-specific molecular features of lupus nephritis and developed a blood-based algorithm for early diagnosis and therapeutic intervention. This may facilitate prevention and early intervention trials for LN.
ANNALS OF THE RHEUMATIC DISEASES
(2022)
Article
Cardiac & Cardiovascular Systems
Yosuke Terui, Koichiro Sugimura, Hideki Ota, Hiroshi Tada, Kotaro Nochioka, Haruka Sato, Yuko Katsuta, Junko Fujiwara, Narumi Harada-Shoji, Akiko Sato-Tadano, Yoshiaki Morita, Wenyu Sun, Satoshi Higuchi, Shunsuke Tatebe, Shigefumi Fukui, Saori Miyamichi-Yamamoto, Hideaki Suzuki, Nobuhiro Yaoita, Nobuhiro Kikuchi, Miku Sakota, Satoshi Miyata, Yasuhiko Sakata, Takanori Ishida, Kei Takase, Satoshi Yasuda, Hiroaki Shimokawa
Summary: The study evaluated the usefulness of cardiac magnetic resonance (CMR) and biomarkers analysis for early detection of chemotherapy-related cardiac dysfunction (CTRCD) in breast cancer patients. The results showed that CMR is effective in detecting chemotherapy-related myocardial damage and predicting the development of CTRCD.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Medicine, General & Internal
Mihai-Andrei Lazar, Ioana Ionac, Constantin-Tudor Luca, Lucian Petrescu, Cristina Vacarescu, Simina Crisan, Dan Gaita, Dragos Cozma, Raluca Sosdean, Diana-Aurora Arnautu, Alina-Ramona Cozlac, Slivia-Ana Luca, Andra Gurgu, Claudia Totorean, Cristian Mornos
Summary: This study investigated the role of speckle-tracking echocardiography (STE) in predicting cardiac remodeling in STEMI patients after percutaneous coronary intervention (PCI). The results showed that age, triglyceride level, and midmyocardial radial strain were risk factors for adverse remodeling, while increased initial twist decreased the chances of adverse remodeling.
Article
Cardiac & Cardiovascular Systems
Guy Baruch, Ehud Rothschild, Sapir Sadon, Yishay Szekely, Yael Lichter, Alon Kaplan, Philippe Taieb, Ariel Banai, Aviram Hochstadt, Ilan Merdler, Yaron Arbel, Michal Laufer-Perl, Gil Beer, Livia Kapusta, Yan Topilsky
Summary: This study assessed changes in echocardiographic parameters in COVID-19 patients during hospitalization and at 3-month follow-up. The results showed significant improvement in some right ventricle parameters at follow-up, while left ventricle parameters did not change significantly. Approximately a quarter of the patients still had left ventricle systolic dysfunction, suggesting subclinical LV dysfunction may be a part of COVID-19 recovery.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2022)
Article
Medicine, General & Internal
Rebecca Heijke, Awais Ahmad, Martina Frodlund, Lina Wirestam, Orjan Dahlstrom, Charlotte Dahle, Stergios Kechagias, Christopher Sjowall
Summary: This study found that AIH and PBC were highly overrepresented in SLE patients compared to the general Swedish population, suggesting that the diagnostic criteria for AIH may need to be improved to reduce false positives and emphasize the importance of liver biopsy and detection of other AILD-associated autoantibodies.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Agriculture, Dairy & Animal Science
Lina Hamabe, Ahmed S. Mandour, Kazumi Shimada, Akiko Uemura, Zeki Yilmaz, Kentaro Nagaoka, Ryou Tanaka
Summary: Two-dimensional speckle-tracking echocardiography is an advanced imaging technique that allows comprehensive evaluation of myocardial function through deformation imaging. It has gained importance in human medicine over the past decade, with applications for assessing myocardial function, detecting subclinical dysfunction, and as a prognostic indicator. In veterinary medicine, it is particularly useful for early detection of left ventricular dysfunction in dogs.
Article
Cardiac & Cardiovascular Systems
Jun Zhang, Xin Li, Juan Liu, Yongning Shang, Lin Tan, Yanli Guo
Summary: This study investigated the early changes in cardiac function and blood flow in a rat model of doxorubicin-induced cardiotoxicity using myocardial contrast echocardiography (MCE). The results showed that MCE accurately and non-invasively detected the decreased myocardial blood flow and left ventricular dysfunction associated with doxorubicin treatment. This suggests the clinical potential of MCE for continuous monitoring of doxorubicin-induced cardiotoxicity.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jia Liu, Yukun Cao, Kuikui Zhu, Sheng Yao, Mei Yuan, Xiangchuang Kong, Xiaoming Liu, Yumin Li, Yue Cui, Xiaoyu Han, Xiaoyue Zhou, Rui Meng, Heshui Shi
Summary: This study aimed to evaluate the subclinical cardiotoxicity of immune checkpoint inhibitors (ICIs) in cancer patients using cardiovascular magnetic resonance (CMR) and investigate whether CMR parameters can predict cardiotoxicity in the early stage of ICI therapy. The study found that the relative reduction of left ventricular-global radial strain (LV-GRS) at the second follow-up can be used as a predictor for the development of cardiotoxicity three months after ICI therapy.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2022)
Article
Medicine, General & Internal
Archana Sharma-Oates, Dawit T. Zemedikun, Kanta Kumar, John A. Reynolds, Avinash Jain, Karim Raza, John A. Williams, Laura Bravo, Victor Roth Cardoso, Georgios Gkoutos, Krishnarajah Nirantharakumar, Janet M. Lord
Summary: Individuals from non-White ethnic groups in the UK were diagnosed with common IMDs at an earlier age than their White counterparts.
Article
Clinical Neurology
Sarah P. Griffith, Robb Wesselingh, Nabil Seery, Tiffany Rushen, Chris Kyndt, Brian Long, Udaya Seneviratne, Katherine Buzzard, Helmut Butzkueven, Terence J. O'Brien, Rubina Alpitsis, Charles B. Malpas, Mastura Monif
Summary: This study used the Wechsler intelligence and memory scales to assess the cognitive function of patients with chronic autoimmune encephalitis (AE). The results showed significantly reduced performances in perceptual reasoning, processing speed, and working memory among AE patients. Pattern analysis revealed positive long-term cognitive outcomes for most patients, but varied outcomes for those with ongoing difficulties.
JOURNAL OF NEUROLOGY
(2023)
Review
Immunology
Yinyun Lu, Yongchun Ruan, Pan Hong, Ke Rui, Qi Liu, Shengjun Wang, Dawei Cui
Summary: Senescent T cells, which lack antigen-specific responses, contribute to immunological disorders and disease progression in autoimmune diseases. These T cells lack costimulatory markers, have reduced T cell receptor repertoire, and uptake of natural killer cell receptors. They exert cytotoxic effects without antigen-presenting process by expressing molecules such as perforin, granzymes, tumor necrosis factor, etc. Senescent T cells exhibit features like DNA damage accumulation, telomere damage, and limited DNA repair capacity. Impaired mitochondrial function and accumulation of reactive oxygen species also contribute to T cell senescence. Alleviating T-cell senescence could provide potential targets for the treatment of autoimmune diseases.
CLINICAL IMMUNOLOGY
(2023)
Article
Chemistry, Physical
Yichuan Wang, Zeyue Wei, Xuanyu Zhang, Weixin Huang
Summary: A series of heteropoly acids were prepared for the oxidation of isobutane to MAA. Cs2.23Cu0.26V0.38PMo12O40 catalyst showed a 20% conversion of isobutane and a 51% selectivity for MAA at 335 degrees C, resulting in a MAA yield of 0.68 mmol(MAA)center dot h(-1)center dot g(catalyst)(-1). The mobility of lattice oxygen and the acidity of the catalysts played crucial roles in the selective oxidation process.
APPLIED CATALYSIS A-GENERAL
(2023)
Article
Environmental Sciences
Shan Yu, Wala Du, Xiang Zhang, Ying Hong, Yang Liu, Mei Hong, Siyu Chen
Summary: Vegetation is crucial for linking various environmental factors and plays a significant role in climate change adaptation and sustainable development. However, little is known about vegetation vulnerability and its driving mechanisms. Therefore, a study was conducted to analyze temporal and spatial changes in vegetation and the factors influencing these changes in the Kherlen River Basin using remote sensing data. The results indicate that the long-term normalized difference vegetation index (NDVI) remained stable in the basin, with a significant mutation period from 2013 to 2017. The key factors affecting NDVI in the basin were temperature and precipitation, which directly influenced the local vegetation. The findings contribute to a better understanding of vegetation change mechanisms and can inform ecological policy-making.
CHINESE GEOGRAPHICAL SCIENCE
(2023)
Article
Energy & Fuels
Shan Li, Mengqian Lu, Peng Wu, Shuquan Zhu, Cai Tie, Xuanhe Zhao, Handong Liang
Summary: Low-temperature pyrolysis is an important technology for the clean and efficient utilization of lignite. This study investigates the concentration and composition of polycyclic aromatic hydrocarbons (PAHs) in lignites and their semi-cokes, and finds that the PAHs in the semi-coke are closely related to the macromolecular structure of raw coal, providing valuable information for the structural evolution of coal during pyrolysis and the development of clean fuel.
Article
Materials Science, Characterization & Testing
Zichao Wang, Xuan Zhang, Zhenzhen Wu, Tong Wang, Yan Li, Liusiyuan He, Xiuzhong Zhu, Xiaodong Fan
Summary: The synthesis of a functional polybutadiene derivative containing anthracenic acid and azide groups was achieved through an electrophilic reaction. This derivative was then reacted with alkynyl-terminated polytetrahydrofuran and maleimideterminated polyethylene glycol through azide-alkyne and Diels-Alder click reaction to obtain a bottle-brush polymer. The self-assembly of the bottle-brush polymer into uniform nanomicelles in aqueous solution and the photoregulated fluorescence resonance energy transfer exhibited by these micelles were studied.
Article
Construction & Building Technology
Xuanyu Zhang, Kezhen Yan, Wenyao Liu
Summary: This study explored the use of recycled rice husk ash (RHA) and recycled asphalt pavement (RAP) in cement-stabilized macadam (CSM) for producing a pavement base material. Laboratory experiments were conducted to investigate the strength, flexibility, shrinkage, and resistance to temperature variation of the CSM samples with different proportions of RHA (0%, 20%, 40%, 60%, and 80% by weight of cement) and RAP (40% by weight of natural aggregates). The results showed that the addition of RHA decreased the increasing rate and strength after curing, but 20% or lower content of RHA could still maintain the resistance to thermal changes, moisture loss, and freeze-thaw cycle. It is suggested that replacing 20% of cement with RHA and 40% of natural aggregates with RAP can produce qualified and environmentally friendly pavement base material.
ROAD MATERIALS AND PAVEMENT DESIGN
(2023)
Review
Biology
Yeting Sun, Yeshuang Yuan, Bo Zhang, Xuan Zhang
Summary: The development of CAR-based therapeutic interventions has revolutionized cancer treatment and has also shown potential in treating autoimmune diseases. CAR-T cells can effectively deplete pathological immune cells, while CAR-Tregs have the ability to restore immune tolerance. The optimization of CAR structure and function has been influenced by previous experience in the field of cancer. This review discusses the potential application of CAR-T cells and CAR-Tregs in treating autoimmune diseases, as well as the strategies of gene editing and synthetic biological tools that have improved CAR-based therapies.
SCIENCE CHINA-LIFE SCIENCES
(2023)
Article
Environmental Sciences
Cha Ersi, Tubuxin Bayaer, Yuhai Bao, Yulong Bao, Mei Yong, Quan Lai, Xiang Zhang, Yusi Zhang
Summary: Phenological parameters can vary when estimated from different data in response to climatic factors. In this study, we estimated the start (SOS) and end (EOS) of the growing season using sunlight-induced chlorophyll fluorescence (SIF), normalized difference vegetation index (NDVI), and near-infrared reflectance of vegetation (NIRv). We detected breakpoints and analyzed the trends and change-points of phenological parameters based on these data. We also analyzed the correlations between phenological parameters and snow-related factors, precipitation, temperature, soil moisture, and population density. The results reveal the differences and potentials of different remote-sensing parameters in estimating phenological indicators and provide insights into the dynamic changes in phenology and response to various influencing factors.
Article
Oncology
Renyi Su, Huizhong Zhang, Lincheng Zhang, Abdul Rehman Khan, Xuanyu Zhang, Rui Wang, Chuxiao Shao, Xuyong Wei, Xiao Xu
Summary: A ceRNA regulatory network, involving PVT1/miR-1258/DUSP13 axis, was found to be significantly associated with the progression of MVI in HCC patients. This finding provides new insight into the tumor invasion mechanism in liver cancer.
Editorial Material
Immunology
Lidan Zhao, Aleksandar David Kostic, Xuan Zhang
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Rheumatology
Saeko Yamada, Yasuo Nagafuchi, Min Wang, Mineto Ota, Hiroaki Hatano, Yusuke Takeshima, Mai Okubo, Satomi Kobayashi, Yusuke Sugimori, Nakano Masahiro, Ryochi Yoshida, Norio Hanata, Yuichi Suwa, Yumi Tsuchida, Yukiko Iwasaki, Shuji Sumitomo, Kanae Kubo, Kenichi Shimane, Keigo Setoguchi, Takanori Azuma, Hiroko Kanda, Hirofumi Shoda, Xuan Zhang, Kazuhiko Yamamoto, Kazuyoshi Ishigaki, Tomohisa Okamura, Keishi Fujio
Summary: By analyzing the transcriptome of peripheral blood immune cell subsets in patients with rheumatoid arthritis (RA), immune cells that predict treatment resistance were identified. Changes in the transcriptome and treatment effects in RA were characterized. Plasmacytoid dendritic cells (pDC) showed the strongest association with treatment resistance. The predictive value of pDC-related gene expression and pDC proportion in treatment-resistant patients was validated in independent cohorts.
ANNALS OF THE RHEUMATIC DISEASES
(2023)
Article
Immunology
Minghua Zhan, Ziwei Wang, Huizhang Bao, Chun Di, Changsheng Xia, Xuan Zhang, Yudong Liu
Summary: Autoantibodies against NETs (ANETA) are present in SLE patients, and their presence can enhance the clinical performance of anti-dsDNA antibodies in identifying subsets of SLE patients with higher disease activity and hematological abnormalities.
CLINICAL IMMUNOLOGY
(2023)
Review
Engineering, Chemical
Zhicheng Hu, Dongfang Lu, Xiayu Zheng, Yuhua Wang, Zixing Xue, Shaohua Xu
Summary: High-gradient magnetic separation (HGMS) is commonly used for selectively enriching fine weakly magnetic minerals and purifying non-metal ores. To address the challenges posed by declining grades and low-grade orebodies, improved selectivity is needed to keep HGMS competitive. This review summarizes efforts in selective separation of HGMS, including reasons for deteriorating selectivity, effects of applied forces, methods of improving selectivity, and industrial separators. Future trends should focus on highly selective separation of ultrafine materials through particle dispersion, increasing magnetic field force, and introducing more efficient competitive forces, which could expand the applicability of HGMS in various industrial fields.
Article
Nuclear Science & Technology
Qiuyu Zheng, Xiaofeng Zhao, Yang Liu, Yuancheng Teng, Yuxiang Li, Guangyuan Liu, Xiayu Zheng, Wei Luo, Rajeev Ahuja
Summary: Rhabdophane LnPO(4)center dot 0.667H(2)O is an effective precipitation-enrichment barrier for isolating actinides from groundwater. By studying the precipitation behavior of NdxSmxLa(1-2x)PO(4)center dot 0.667H(2)O solid solutions, it was found that the removal rate of Nd3+ and Sm3+ can reach over 99% in a solution with approximately pH = 1. Refined XRD analysis confirmed the presence of single-phase NdxSmxLa12xPO4 center dot 0.667H(2)O, although the composition distribution of nanograins is extremely uneven.
PROGRESS IN NUCLEAR ENERGY
(2023)
Article
Chemistry, Multidisciplinary
Chen Sun, Zeyu Deng, Zhiyuan Li, Zhongwei Chen, Xuanyu Zhang, Jian Chen, Haipeng Lu, Pieremanuele Canepa, Rui Chen, Lingling Mao
Summary: Hybrid organic-inorganic antimony halides with high photoluminescence quantum yield (PLQY) have gained attention for their non-toxicity and stability. Five pairs of antimony halides with different structures were synthesized and characterized to investigate the factors contributing to high PLQY. The antimony halides with square pyramidal geometry exhibited near-unity PLQY, while those with seesaw dimmer geometry showed PLQY close to 0%. The longer Sb center dot center dot center dot Sb distances in the square pyramidal structures and other factors such as Sb-Cl distance and stability of antimony chlorides may influence PLQY. The findings provide valuable insights for the precise design of highly emissive materials in optoelectronic applications.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Immunology
Xuan Zhang, Jun Xia, Ying Jiang, David S. Pisetsky, Josef S. Smolen, Rong Mu, Shengming Dai, Michael E. Weinblatt, Tore K. Kvien, Juan Li, Thomas Doerner, Yu Zhang, Liwei Lu, Chengde Yang, Pingting Yang, Yuan Zhang, Chenchen Xu, Zhan Zhao, Peter E. Lipsky
Summary: The study suggests that TwHF may be as effective as MTX in treating active RA, and combination therapy may be more effective than monotherapy.
JOURNAL OF AUTOIMMUNITY
(2024)
Editorial Material
Cardiac & Cardiovascular Systems
Jose E. Exaire, Timothy A. Mixon
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Giuseppe Di Gioia, Federica Coletti, Lorenzo Buzzelli, Viviana Maestrini, Sara Monosilio, Andrea Segreti, Maria Rosaria Squeo, Erika Lemme, Antonio Nenna, Antonio Pelliccia
Summary: Dyslipidemia is common in Paralympic athletes, with lipid levels influenced by the type of disability and sporting discipline.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Esra Donmez, Sevgi Ozcan, Irfan Sahin, Murat Ziyrek, Ertugrul Okuyan
Summary: This study aimed to evaluate the predictive value of the GRACE risk score in acute pulmonary embolism (PE) patients for 30-day mortality and the need for thrombolytic treatment. The study found that the GRACE risk score, along with the PESI score, were independent risk factors associated with 30-day mortality and the need for thrombolytic treatment. The GRACE risk score showed high sensitivity and specificity in predicting mortality, and its combination with the PESI score helped define high-risk PE patients and predict poor prognosis.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Tom Kai Ming Wang, Reza Reyaldeen, Kevser Akyuz, Zoran B. Popovic, A. Marc Gillinov, Bo Xu, Brian P. Griffin, Milind Y. Desai
Summary: Transthoracic echocardiography (TTE) is commonly used to evaluate isolated tricuspid regurgitation (TR), but there is limited research comparing its quantification with magnetic resonance imaging (MRI). In this study, a novel TTE algorithm was developed to identify severe TR based on TTE parameters. The algorithm had a higher accuracy than the current guidelines' criteria in detecting severe TR by MRI.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Editorial Material
Cardiac & Cardiovascular Systems
Enkhtsogt Sainbayar, Ramzi Ibrahim, Hoang Nhat Pham, Wisam Beauti, Mahek Shahid, Natalie Hickerson, Mohammed Salih, Joao Paulo Ferreira, Mamas A. Mamas
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Richard E. Casazza, Hymie Chera, Carlos Adolfo Rodriguez, Sergey Ayzenberg
Summary: This article presents a case of a patient with known situs inversus who underwent cardiac catheterization and was found to have chronic total occlusion in the right coronary artery. Situs inversus is a rare congenital abnormality characterized by the inverted position of chest and abdominal organs. Cardiac catheterization is uncommon in patients with this particular abnormality, highlighting the importance of customizing techniques to engage coronary arteries and optimize guide support for percutaneous coronary intervention if needed.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Editorial Material
Cardiac & Cardiovascular Systems
Georgiana Pintea Bentea, Brahim Berdaoui, Sophie Samyn, Marielle Morissens, Philippe van de Borne, Jose Castro Rodriguez
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Bulbul Ahmed, Melissa G. Farb, Shakun Karki, Sophia D'Alessandro, Niloo M. Edwards, Noyan Gokce
Summary: This study evaluated the angiogenic capacity of adipose tissue in patients undergoing cardiac surgeries and found that patients with coronary artery disease (CAD) had reduced angiogenic capacity in their pericardial adipose tissue. Gene expression analysis revealed upregulated expression of the anti-angiogenic gene TSP-1 in CAD patients, with no significant differences in other angiogenic factors. Additionally, inhibiting TSP-1 expression significantly improved angiogenic deficiency in CAD patients.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Moshe Rav-Acha, Orli Wube, Oholi Tovia Brodie, Yoav Michowitz, Michael Ilan, Tal Ovdat, Robert Klempfner, Mahmud Suleiman, Ilan Goldenberg, Michael Glikson
Summary: The current guidelines recommend prophylactic implantable cardioverter-defibrillator (ICD) for patients with symptomatic heart failure (HF) and low left ventricular ejection fraction. However, not all patients will benefit from ICD treatment. This study evaluated the feasibility of using the MADIT-II-based Risk Stratification Score (MRSS) to predict the survival benefit of prophylactic ICDs in patients with HF. The results showed that different risk subgroups had varying levels of ICD survival benefit.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Ariel Banai, Rachel Retsky, Lior Lupu, Erez Levi, David Zahler, Omri Feder, Roei Merin, Yan Topilsky, Raphael Rosso, Shmuel Banai, Sami Viskin, Ehud Chorin
Summary: This study aims to evaluate the association between electromechanical window (EMW) and ventricular tachyarrhythmias in patients with Takotsubo syndrome (TTS). The study found that TTS patients had a lower EMW value, which was associated with an increased risk of ventricular tachyarrhythmias.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Harun Kundi, Kobina Hagan, Tamer Yahya, Garima Sharma, Sadeer Al-Kindi, Zulqarnain Javed, Khurram Nasir
Summary: Using latent class analysis (LCA), the study identified clinical, demographic, and social subphenotypes in ASCVD population and assessed the risk of all-cause and cardiovascular mortality across different socioclinical classes. The results showed that the younger, female, non-Hispanic Black or Hispanic individuals with a high burden of co-morbidities and unfavorable social determinants of health had the highest risk of mortality in the identified latent classes.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Moises A. Vasquez, Mina Iskander, Mohammed Mustafa, Juan A. Quintero-Martinez, Antonio Luna, Joel Mintz, Jose Noy, Juan Uribe, Ivan Mijares, Eduardo de Marchena, Yiannis S. Chatzizisis
Summary: The benefits of pericardiocentesis (PC) in patients with pulmonary hypertension (PH) and pericardial effusions are unclear. The study found that PC in PH patients is associated with higher in-hospital mortality and rates of cardiovascular complications.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Ken Kuwajima, Mana Ogawa, Irving Ruiz, Hiroko Hasegawa, Nobuichiro Yagi, Florian Rader, Robert J. Siegel, Takahiro Shiota
Summary: After cardiac surgery, the longitudinal function of the right ventricle and left ventricle is reduced, despite preserved global functions. In particular, tricuspid annular plane systolic excursion (TAPSE) remains decreased after surgery.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Min -Jung Kim, Robert H. Aseltine Jr, Sara R. Tabtabai
Summary: This study evaluated the rates and causes of 30-day readmissions after discharge for heart failure (HF) as a primary and secondary diagnosis. The findings indicate that efforts to reduce readmission rates should include patients with secondary HF diagnosis, and surveillance should extend to 2 weeks postdischarge to identify at-risk patients.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Ya He, Jianzhong Zhou
Summary: This study aimed to examine the relation between reverse septal curvature (RSC) and nonsustained ventricular tachycardia (NSVT) in patients with hypertrophic cardiomyopathy (HCM). The study found that patients with RSC were younger and had a higher incidence of NSVT, and RSC was identified as a strong independent risk factor for NSVT.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
