Heterodimerization of Mu Opioid Receptor Protomer with Dopamine D2 Receptor Modulates Agonist-Induced Internalization of Mu Opioid Receptor

Distinct Dopamine D2 Receptor Antagonists Differentially Impact D2 Receptor Oligomerization

(2019) Elise Wouters et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

D2-like receptor agonist synergizes the μ-opioid agonist spinal antinociception in nociceptive, inflammatory and neuropathic models of pain in the rat

(2019) Jonathan Mercado-Reyes et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Design, Synthesis, and Biological Evaluation of Bivalent Ligands Targeting Dopamine D2 -Like Receptors and the μ-Opioid Receptor

(2018) Mingcheng Qian et al.   ChemMedChem

Mapping the Interface of a GPCR Dimer: A Structural Model of the A2A Adenosine and D2 Dopamine Receptor Heteromer

(2018) Dasiel O. Borroto-Escuela et al.   Frontiers in Pharmacology

Historical Review

(2018) Shaocheng Wang   CELL TRANSPLANTATION

An Expanding World of Novel Psychoactive Substances: Opioids

(2017) Jolanta B. Zawilska   Frontiers in Psychiatry

Dopamine D4 receptor stimulation prevents nigrostriatal dopamine pathway activation by morphine: relevance for drug addiction

(2016) Alicia Rivera et al.   ADDICTION BIOLOGY

Opioid Receptors

(2016) Christoph Stein   Annual Review of Medicine

Blockade of neuronal dopamine D2 receptor attenuates morphine tolerance in mice spinal cord

(2016) Wen-Ling Dai et al.   Scientific Reports

l-DOPA disrupts adenosine A2A–cannabinoid CB1–dopamine D2 receptor heteromer cross-talk in the striatum of hemiparkinsonian rats: Biochemical and behavioral studies

(2014) Annalisa Pinna et al.   EXPERIMENTAL NEUROLOGY

Enhancement of morphine analgesia and prevention of morphine tolerance by downregulation of β-arrestin 2 with antigene RNAs in mice

(2014) Huilian Bu et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Single-molecule imaging revealed dynamic GPCR dimerization

(2013) Rinshi S Kasai et al.   CURRENT OPINION IN CELL BIOLOGY

Palmitoylation and membrane cholesterol stabilize μ-opioid receptor homodimerization and G protein coupling

(2012) Hui Zheng et al.   BMC CELL BIOLOGY

Analgesic Tolerance to High-Efficacy Agonists But Not to Morphine Is Diminished in Phosphorylation-Deficient S375A  -Opioid Receptor Knock-In Mice

(2011) G. Grecksch et al.   JOURNAL OF NEUROSCIENCE

The Physiology, Signaling, and Pharmacology of Dopamine Receptors

(2011) J.-M. Beaulieu et al.   PHARMACOLOGICAL REVIEWS

Functional Selectivity at the  -Opioid Receptor: Implications for Understanding Opioid Analgesia and Tolerance

(2011) K. M. Raehal et al.   PHARMACOLOGICAL REVIEWS

Dopamine D2 and D4 receptor heteromerization and its allosteric receptor–receptor interactions

(2010) Dasiel O. Borroto-Escuela et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hetero-dimerization of serotonin 5-HT2A and dopamine D2 receptors

(2010) Sylwia Łukasiewicz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Opioid–Dopamine Interactions: Implications for Substance Use Disorders and Their Treatment

(2010) Nora D. Volkow   BIOLOGICAL PSYCHIATRY

 -Opioid Receptors: Correlation of Agonist Efficacy for Signalling with Ability to Activate Internalization

(2010) J. McPherson et al.   MOLECULAR PHARMACOLOGY

Uncoupling the dopamine D1-D2 receptor complex exerts antidepressant-like effects

(2010) Lin Pei et al.   NATURE MEDICINE

Improvement of Morphine-Mediated Analgesia by Inhibition of β-Arrestin 2 Expression in Mice Periaqueductal Gray Matter

(2009) Yuting Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Analysis of receptor oligomerization by FRAP microscopy

(2009) Sandra Dorsch et al.   NATURE METHODS

HaloTag: A Novel Protein Labeling Technology for Cell Imaging and Protein Analysis

(2008) Georgyi V. Los et al.   ACS Chemical Biology

Receptor–receptor interactions within receptor mosaics. Impact on neuropsychopharmacology

(2008) K. Fuxe et al.   BRAIN RESEARCH REVIEWS

Cellular neuroadaptations to chronic opioids: tolerance, withdrawal and addiction

(2008) M J Christie   BRITISH JOURNAL OF PHARMACOLOGY

Agonist-selective mechanisms of GPCR desensitization

(2007) E Kelly et al.   BRITISH JOURNAL OF PHARMACOLOGY

Role of receptor internalization in opioid tolerance and dependence

(2007) Thomas Koch et al.   PHARMACOLOGY & THERAPEUTICS