Development of a Bispecific Antibody Targeting CD30 and CD137 on Hodgkin and Reed-Sternberg Cells
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Title
Development of a Bispecific Antibody Targeting CD30 and CD137 on Hodgkin and Reed-Sternberg Cells
Authors
Keywords
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Journal
Frontiers in Oncology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2019-09-24
DOI
10.3389/fonc.2019.00945
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- Targeting Immune System Alterations in Hodgkin Lymphoma
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- Five-year survival and durability results of brentuximab vedotin in patients with relapsed or refractory Hodgkin lymphoma
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- Microenvironmental interactions in classical Hodgkin lymphoma and their role in promoting tumor growth, immune escape and drug resistance
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- (2014) Angeline XH Goh et al. mAbs
- Finding a needle in a haystack
- (2014) Qunrui Ye et al. OncoImmunology
- CD137 Is Expressed in Follicular Dendritic Cell Tumors and in Classical Hodgkin and T-Cell Lymphomas
- (2012) Matthew W. Anderson et al. AMERICAN JOURNAL OF PATHOLOGY
- Expression of CD137 on Hodgkin and Reed-Sternberg Cells Inhibits T-cell Activation by Eliminating CD137 Ligand Expression
- (2012) W. T. Ho et al. CANCER RESEARCH
- Hodgkin lymphoma
- (2012) Ralf Küppers et al. JOURNAL OF CLINICAL INVESTIGATION
- Results of a Pivotal Phase II Study of Brentuximab Vedotin for Patients With Relapsed or Refractory Hodgkin's Lymphoma
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- The discovery and development of brentuximab vedotin for use in relapsed Hodgkin lymphoma and systemic anaplastic large cell lymphoma
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- Immunoglobulin domain crossover as a generic approach for the production of bispecific IgG antibodies
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