CTCs 2020: Great Expectations or Unreasonable Dreams

Circulating Tumor Cell Clustering Shapes DNA Methylation to Enable Metastasis Seeding

(2019) Sofia Gkountela et al.   CELL

Circulating tumor stem cells and glioblastoma: A review

(2019) Bede van Schaijik et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Neutrophils escort circulating tumour cells to enable cell cycle progression

(2019) Barbara Maria Szczerba et al.   NATURE

Label-Free Enrichment and Molecular Characterization of Viable Circulating Tumor Cells from Diagnostic Leukapheresis Products

(2019) André Franken et al.   CLINICAL CHEMISTRY

Promises and Pitfalls of Using Liquid Biopsy for Precision Medicine

(2019) Giovanna Rossi et al.   CANCER RESEARCH

Synchronous detection of circulating tumor cells in blood and disseminated tumor cells in bone marrow predict adverse outcome in early breast cancer

(2019) Mark Jesus M. Magbanua et al.   CLINICAL CANCER RESEARCH

Unexpected Friendship: Neutrophils Help Tumor Cells En Route to Metastasis

(2019) Oihana Iriondo et al.   DEVELOPMENTAL CELL

Androgen receptor variant 7 (AR-V7) in sequencing therapeutic agents for castratrion resistant prostate cancer

(2019) Alessandro Sciarra et al.   MEDICINE

Detection of circulating tumor cells in colorectal cancer patients using the Gilupi CellCollector: Results from a prospective, single center study

(2019) Levent Dizdar et al.   Molecular Oncology

Metastasis Stemming from Circulating Tumor Cell Clusters

(2019) Min Yu   TRENDS IN CELL BIOLOGY

Heterogeneity in Circulating Tumor Cells: The Relevance of the Stem-Cell Subset

(2019) Chiara Agnoletto et al.   Cancers

The identification of a TNBC liver metastasis gene signature by sequential CTC‐xenograft modeling

(2019) Monika Vishnoi et al.   Molecular Oncology

In vivo liquid biopsy using Cytophone platform for photoacoustic detection of circulating tumor cells in patients with melanoma

(2019) Ekaterina I. Galanzha et al.   Science Translational Medicine

Diagnostic Leukapheresis Enables Reliable Transcriptomic Profiling of Single Circulating Tumor Cells to Characterize Inter-Cellular Heterogeneity in Terms of Endocrine Resistance

(2019) Florian Reinhardt et al.   Cancers

Prognostic Significance of TWIST1, CD24, CD44, and ALDH1 Transcript Quantification in EpCAM-Positive Circulating Tumor Cells from Early Stage Breast Cancer Patients

(2019) Areti Strati et al.   Cells

Clinical Impact of Circulating Tumor Cells in Patients with Localized Prostate Cancer

(2019) Broncy et al.   Cells

Hybrid epithelial/mesenchymal phenotype(s): The ‘fittest’ for metastasis?

(2018) Mohit Kumar Jolly et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Towards a real liquid biopsy in metastatic breast and prostate cancer: Diagnostic LeukApheresis increases CTC yields in a European prospective multi-center study (CTCTrap)

(2018) Kiki C. Andree et al.   INTERNATIONAL JOURNAL OF CANCER

Circulating Tumor Cell Number as a Response Measure of Prolonged Survival for Metastatic Castration-Resistant Prostate Cancer: A Comparison With Prostate-Specific Antigen Across Five Randomized Phase III Clinical Trials

(2018) Glenn Heller et al.   JOURNAL OF CLINICAL ONCOLOGY

The viable circulating tumor cells with cancer stem cells feature, where is the way out?

(2018) Y. T. Luo et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

PD-L1 expression in circulating tumor cells of advanced non-small cell lung cancer patients treated with nivolumab

(2018) Nicolas Guibert et al.   LUNG CANCER

Evaluation of PD-L1/PD-1 on circulating tumor cells in patients with advanced non-small cell lung cancer

(2018) Galatea Kallergi et al.   Therapeutic Advances in Medical Oncology

Dynamic change of PD-L1 expression on circulating tumor cells in advanced solid tumor patients undergoing PD-1 blockade therapy

(2018) Chunyan Yue et al.   OncoImmunology

Cancer stem cells: A brief review of current status

(2018) Alican Kuşoğlu et al.   GENE

Health economic impact of liquid biopsies in cancer management

(2018) Maarten J. IJzerman et al.   Expert Review of Pharmacoeconomics & Outcomes Research

Diagnostic leukapheresis for CTC analysis in breast cancer patients: CTC frequency, clinical experiences and recommendations for standardized reporting

(2018) Tanja N. Fehm et al.   CYTOMETRY PART A

Therapy resistance mediated by cancer stem cells

(2018) Teresa Bernadette Steinbichler et al.   SEMINARS IN CANCER BIOLOGY

EMT Transition States during Tumor Progression and Metastasis

(2018) Ievgenia Pastushenko et al.   TRENDS IN CELL BIOLOGY

The clinical use of circulating tumor cells (CTCs) enumeration for staging of metastatic breast cancer (MBC): International expert consensus paper

(2018) Massimo Cristofanilli et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Circulating tumor cells: clinical validity and utility

(2017) Luc Cabel et al.   International Journal of Clinical Oncology

Circulating and disseminated tumor cells: harbingers or initiators of metastasis?

(2017) Arko Dasgupta et al.   Molecular Oncology

The challenge of targeting cancer stem cells to halt metastasis

(2017) Alice Agliano et al.   SEMINARS IN CANCER BIOLOGY

Molecular heterogeneity in breast cancer: State of the science and implications for patient care

(2017) Rachel E. Ellsworth et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Characterization of Tumor Cells Using a Medical Wire for Capturing Circulating Tumor Cells: A 3D Approach Based on Immunofluorescence and DNA FISH

(2017) Giulia Gallerani et al.   Jove-Journal of Visualized Experiments

CTLA-4 and PD-1 Pathways

(2016) Elizabeth I. Buchbinder et al.   AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS

Liquid Biopsy in Lung Cancer: A Perspective From Members of the Pulmonary Pathology Society

(2016) Lynette M. Sholl et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

Metastasis: new functional implications of platelets and megakaryocytes

(2016) Raphael Leblanc et al.   BLOOD

Circulating Cancer-Associated Macrophage-Like Cells Differentiate Malignant Breast Cancer and Benign Breast Conditions

(2016) D. L. Adams et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

The bad seed: Cancer stem cells in tumor development and resistance

(2016) Elle Koren et al.   DRUG RESISTANCE UPDATES

A comparison of CellCollector with CellSearch in patients with neuroendocrine tumours

(2016) D Mandair et al.   ENDOCRINE-RELATED CANCER

Metastasis: an early event in cancer progression

(2016) Yijun Hu et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

CTC immune escape mediated by PD-L1

(2016) Xuefei Wang et al.   MEDICAL HYPOTHESES

Circulating tumor cells in breast cancer

(2016) Francois-Clement Bidard et al.   Molecular Oncology

Metastatic colonization by circulating tumour cells

(2016) Joan Massagué et al.   NATURE

Activated tumor cell integrin αvβ3 cooperates with platelets to promote extravasation and metastasis from the blood stream

(2016) Martin R. Weber et al.   THROMBOSIS RESEARCH

Vasculogenic mimicry in small cell lung cancer

(2016) Stuart C. Williamson et al.   Nature Communications

Circulating Tumor Cells (CTC) Are Associated with Defects in Adaptive Immunity in Patients with Inflammatory Breast Cancer

(2016) M Mego et al.   Journal of Cancer

Monitoring PD-L1 positive circulating tumor cells in non-small cell lung cancer patients treated with the PD-1 inhibitor Nivolumab

(2016) Chiara Nicolazzo et al.   Scientific Reports

Improved detection of circulating tumor cells in non-metastatic high-risk prostate cancer patients

(2016) Andra Kuske et al.   Scientific Reports

Meta-analysis of the prognostic value of circulating tumor cells detected with the CellSearch System in colorectal cancer

(2015) Xuanzhang Huang et al.   BMC CANCER

Diversity of assessing circulating tumor cells (CTCs) emphasizes need for standardization: a CTC Guide to design and report trials

(2015) S. Bünger et al.   CANCER AND METASTASIS REVIEWS

Circulating tumor cell thresholds and survival scores in advanced metastatic breast cancer: The observational step of the CirCe01 phase III trial

(2015) C. Helissey et al.   CANCER LETTERS

Circulating tumor cells in early breast cancer: A connection with vascular invasion

(2015) Roberta Maltoni et al.   CANCER LETTERS

Establishment and Characterization of a Cell Line from Human Circulating Colon Cancer Cells

(2015) L. Cayrefourcq et al.   CANCER RESEARCH

Enumeration and Molecular Characterization of Tumor Cells in Lung Cancer Patients Using a Novel In Vivo Device for Capturing Circulating Tumor Cells

(2015) T. M. Gorges et al.   CLINICAL CANCER RESEARCH

Challenges for CTC-based liquid biopsies: low CTC frequency and diagnostic leukapheresis as a potential solution

(2015) Nikolas H. Stoecklein et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Clinical Utility of Circulating Tumor Cells in Metastatic Breast Cancer

(2015) Francois-Clement Bidard et al.   JOURNAL OF CLINICAL ONCOLOGY

Circulating Tumor Cell Biomarker Panel As an Individual-Level Surrogate for Survival in Metastatic Castration-Resistant Prostate Cancer

(2015) Howard I. Scher et al.   JOURNAL OF CLINICAL ONCOLOGY

Use of Biomarkers to Guide Decisions on Systemic Therapy for Women With Metastatic Breast Cancer: American Society of Clinical Oncology Clinical Practice Guideline

(2015) Catherine Van Poznak et al.   JOURNAL OF CLINICAL ONCOLOGY

Frequent expression of PD-L1 on circulating breast cancer cells

(2015) Martine Mazel et al.   Molecular Oncology

EMT, CTCs and CSCs in tumor relapse and drug-resistance

(2015) Abhisek Mitra et al.   Oncotarget

The isolation and characterization of CTC subsets related to breast cancer dormancy

(2015) Monika Vishnoi et al.   Scientific Reports

Tumorigenic potential of circulating prostate tumor cells

(2015) Filipe LF. Carvalho et al.   Oncotarget

Monitoring in Metastatic Breast Cancer: Is Imaging Outdated in the Era of Circulating Tumor Cells?

(2014) Marianna Alunni-Fabbroni et al.   Breast Care

Immune Escape and Survival Mechanisms in Circulating Tumor Cells of Colorectal Cancer

(2014) Gunnar Steinert et al.   CANCER RESEARCH

Circulating Tumor Cell Clusters Are Oligoclonal Precursors of Breast Cancer Metastasis

(2014) Nicola Aceto et al.   CELL

Biology, detection, and clinical implications of circulating tumor cells

(2014) S. A. Joosse et al.   EMBO Molecular Medicine

Clinical validity of circulating tumour cells in patients with metastatic breast cancer: a pooled analysis of individual patient data

(2014) François-Clément Bidard et al.   LANCET ONCOLOGY

Clonal evolution in breast cancer revealed by single nucleus genome sequencing

(2014) Yong Wang et al.   NATURE

Circulating giant macrophages as a potential biomarker of solid tumors

(2014) Daniel L. Adams et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression of Stem Cell and Epithelial-Mesenchymal Transition Markers in Circulating Tumor Cells of Breast Cancer Patients

(2014) Natalia Krawczyk et al.   Biomed Research International

Detection of cancer before distant metastasis

(2013) Frank AW Coumans et al.   BMC CANCER

Tumor Cell Dissemination: Emerging Biological Insights from Animal Models and Cancer Patients

(2013) Yibin Kang et al.   CANCER CELL

Circulating Tumor Cell Isolation: A Marathon Race Worth Running

(2013) E. S. Lianidou   CLINICAL CHEMISTRY

Identification of a population of blood circulating tumor cells from breast cancer patients that initiates metastasis in a xenograft assay

(2013) Irène Baccelli et al.   NATURE BIOTECHNOLOGY

Diagnostic leukapheresis enables reliable detection of circulating tumor cells of nonmetastatic cancer patients

(2013) J. C. Fischer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition

(2013) M. Yu et al.   SCIENCE

Thrombocytosis as a Predictor of Distant Recurrence in Patients with Rectal Cancer

(2012) Adrian Cravioto-Villanueva et al.   ARCHIVES OF MEDICAL RESEARCH

Circulating tumour cells escape from EpCAM-based detection due to epithelial-to-mesenchymal transition

(2012) Tobias M Gorges et al.   BMC CANCER

Intratumor Heterogeneity: Evolution through Space and Time

(2012) C. Swanton   CANCER RESEARCH

Evaluation of Circulating Tumor Cells and Circulating Tumor DNA in Non-Small Cell Lung Cancer: Association with Clinical Endpoints in a Phase II Clinical Trial of Pertuzumab and Erlotinib

(2012) E. A. Punnoose et al.   CLINICAL CANCER RESEARCH

Challenges in the Enumeration and Phenotyping of CTC

(2012) F. A. W. Coumans et al.   CLINICAL CANCER RESEARCH

Beyond Diagnostic Accuracy: The Clinical Utility of Diagnostic Tests

(2012) P. M. M. Bossuyt et al.   CLINICAL CHEMISTRY

Considerations in the development of circulating tumor cell technology for clinical use

(2012) David R Parkinson et al.   Journal of Translational Medicine

Extranodal dissemination of non-Hodgkin lymphoma requires CD47 and is inhibited by anti-CD47 antibody therapy

(2011) M. P. Chao et al.   BLOOD

Direct Signaling between Platelets and Cancer Cells Induces an Epithelial-Mesenchymal-Like Transition and Promotes Metastasis

(2011) Myriam Labelle et al.   CANCER CELL

Platelet-Derived MHC Class I Confers a Pseudonormal Phenotype to Cancer Cells That Subverts the Antitumor Reactivity of Natural Killer Immune Cells

(2011) T. Placke et al.   CANCER RESEARCH

Circulating tumour cells lacking cytokeratin in breast cancer: the importance of being mesenchymal

(2011) Angela Gradilone et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE