Cancer-Derived VEGF-C Increases Chemokine Production in Lymphatic Endothelial Cells to Promote CXCR2-Dependent Cancer Invasion and MDSC Recruitment

Identification of the Novel Role of CD24 as an Oncogenesis Regulator and Therapeutic Target for Triple-Negative Breast Cancer

(2018) Shih-Hsuan Chan et al.   MOLECULAR CANCER THERAPEUTICS

Mechanisms of Tumor-Induced Lymphovascular Niche Formation in Draining Lymph Nodes

(2018) Catharina D. Commerford et al.   Cell Reports

New and developing non-adrenoreceptor small molecule drugs for the treatment of asthma

(2017) Neil C Thomson   EXPERT OPINION ON PHARMACOTHERAPY

S1PR1 on tumor-associated macrophages promotes lymphangiogenesis and metastasis via NLRP3/IL-1β

(2017) Benjamin Weichand et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CXCR2 Inhibition – a novel approach to treating CoronAry heart DiseAse (CICADA): study protocol for a randomised controlled trial

(2017) Jubin P. Joseph et al.   Trials

CXCR2+ MDSCs promote breast cancer progression by inducing EMT and activated T cell exhaustion

(2017) Ha Zhu et al.   Oncotarget

Induction of pro-inflammatory genes by serum amyloid A1 in human amnion fibroblasts

(2017) Wenjiao Li et al.   Scientific Reports

Role of the CXCL8-CXCR1/2 Axis in Cancer and Inflammatory Diseases

(2017) Helen Ha et al.   Theranostics

Interleukin-6 Induces Vascular Endothelial Growth Factor-C Expression via Src-FAK-STAT3 Signaling in Lymphatic Endothelial Cells

(2016) Yu-Han Huang et al.   PLoS One

The prognostic value of CXC-chemokine receptor 2 (CXCR2) in gastric cancer patients

(2015) Zhenglin Wang et al.   BMC CANCER

CD4+T effector memory cell dysfunction is associated with the accumulation of granulocytic myeloid-derived suppressor cells in glioblastoma patients

(2015) Daniel Dubinski et al.   NEURO-ONCOLOGY

Tumor-Induced CD11b+Gr-1+ Myeloid Cells Suppress T Cell Sensitization in Tumor-Draining Lymph Nodes

(2014) S. Watanabe et al.   JOURNAL OF IMMUNOLOGY

A link between inflammation and metastasis: serum amyloid A1 and A3 induce metastasis and are targets of metastasis-inducing S100A4

(2014) M T Hansen et al.   ONCOGENE

Tumor-Derived Interleukin-1 Promotes Lymphangiogenesis and Lymph Node Metastasis through M2-Type Macrophages

(2014) Kosuke Watari et al.   PLoS One

Disruption of CXCR2-Mediated MDSC Tumor Trafficking Enhances Anti-PD1 Efficacy

(2014) S. L. Highfill et al.   Science Translational Medicine

Src contributes to IL6-induced vascular endothelial growth factor-C expression in lymphatic endothelial cells

(2013) Yu-Han Huang et al.   ANGIOGENESIS

CXCR2-Expressing Myeloid-Derived Suppressor Cells Are Essential to Promote Colitis-Associated Tumorigenesis

(2013) Hiroshi Katoh et al.   CANCER CELL

Tumor cell entry into the lymph node is controlled by CCL1 chemokine expressed by lymph node lymphatic sinuses

(2013) Suvendu Das et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tumor-Derived Lactate Modifies Antitumor Immune Response: Effect on Myeloid-Derived Suppressor Cells and NK Cells

(2013) Z. Husain et al.   JOURNAL OF IMMUNOLOGY

High expression of CXCR-2 correlates with lymph node metastasis and predicts unfavorable prognosis in resected esophageal carcinoma

(2013) Ping Sui et al.   MEDICAL ONCOLOGY

A CXCL1 Paracrine Network Links Cancer Chemoresistance and Metastasis

(2012) Swarnali Acharyya et al.   CELL

VEGF-Induced Vascular Permeability Is Mediated by FAK

(2012) Xiao Lei Chen et al.   DEVELOPMENTAL CELL

High expression of CXCR2 is associated with tumorigenesis, progression, and prognosis of laryngeal squamous cell carcinoma

(2012) Liang Han et al.   MEDICAL ONCOLOGY

Clinical significance of sentinel lymph node isolated tumour cells in breast cancer

(2011) Neill Patani et al.   BREAST CANCER RESEARCH AND TREATMENT

Airway inflammation evaluated in a human nasal lipopolysaccharide challenge model by investigating the effect of a CXCR2 inhibitor

(2011) R. Virtala et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Interleukin-6 signalling regulates vascular endothelial growth factor-C synthesis and lymphangiogenesis in human oral squamous cell carcinoma

(2011) Satoru Shinriki et al.   JOURNAL OF PATHOLOGY

Murine Pancreatic Adenocarcinoma Dampens SHIP-1 Expression and Alters MDSC Homeostasis and Function

(2011) Shari Pilon-Thomas et al.   PLoS One

Axillary lymph node dissection for malignant melanoma

(2010) Paul G. Davis et al.   ANZ JOURNAL OF SURGERY

Clinical Importance of Lymph Node Density in Predicting Outcome of Prostate Cancer Patients

(2009) Tommaso Cai et al.   JOURNAL OF SURGICAL RESEARCH

Lymphatic Vessel Activation in Cancer

(2008) Suvendu Das et al.   Annals of the New York Academy of Sciences