No evidence of ongoing HIV replication or compartmentalization in tissues during combination antiretroviral therapy: Implications for HIV eradication

The Spleen Is an HIV-1 Sanctuary During Combined Antiretroviral Therapy

(2018) David J. Nolan et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Novel Latency Reversal Agents for HIV-1 Cure

(2018) Adam M. Spivak et al.   Annual Review of Medicine

Expanded cellular clones carrying replication-competent HIV-1 persist, wax, and wane

(2018) Zheng Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Episomal HIV-1 DNA and its relationship to other markers of HIV-1 persistence

(2018) Javier Martinez-Picado et al.   Retrovirology

No evidence of ongoing evolution in replication competent latent HIV-1 in a patient followed up for two years

(2018) Hoi Ping Mok et al.   Scientific Reports

Barriers and strategies to achieve a cure for HIV

(2018) Matthew C Pitman et al.   Lancet HIV

The Control of HIV after Antiretroviral Medication Pause (CHAMP) study: post-treatment controllers identified from 14 clinical studies

(2018) Golnaz Namazi et al.   JOURNAL OF INFECTIOUS DISEASES

A majority of HIV persistence during antiretroviral therapy is due to infected cell proliferation

(2018) Daniel B. Reeves et al.   Nature Communications

Impact of Allogeneic Hematopoietic Stem Cell Transplantation on the HIV Reservoir and Immune Response in 3 HIV-Infected Individuals

(2017) Kersten K. Koelsch et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

No evidence of HIV replication in children on antiretroviral therapy

(2017) Gert U. Van Zyl et al.   JOURNAL OF CLINICAL INVESTIGATION

HIV persistence: clonal expansion of cells in the latent reservoir

(2017) Kyungyoon J. Kwon et al.   JOURNAL OF CLINICAL INVESTIGATION

Proliferation of latently infected CD4+T cells carrying replication-competent HIV-1: Potential role in latent reservoir dynamics

(2017) Nina N. Hosmane et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tissue Pharmacologic and Virologic Determinants of Duodenal and Rectal Gastrointestinal-Associated Lymphoid Tissue Immune Reconstitution in HIV-Infected Patients Initiating Antiretroviral Therapy

(2017) David M Asmuth et al.   JOURNAL OF INFECTIOUS DISEASES

Characterizing HIV-1 Splicing by Using Next-Generation Sequencing

(2017) Ann Emery et al.   JOURNAL OF VIROLOGY

Re-evaluating evolution in the HIV reservoir

(2017) Daniel I. S. Rosenbloom et al.   NATURE

Proviruses with identical sequences comprise a large fraction of the replication-competent HIV reservoir

(2017) John K. Bui et al.   PLoS Pathogens

Ongoing HIV Replication During ART Reconsidered

(2017) Mary F Kearney et al.   Open Forum Infectious Diseases

HIV Maintains an Evolving and Dispersed Population in Multiple Tissues during Suppressive Combined Antiretroviral Therapy in Individuals with Cancer

(2016) Rebecca Rose et al.   JOURNAL OF VIROLOGY

Persistent HIV-1 replication maintains the tissue reservoir during therapy

(2016) Ramon Lorenzo-Redondo et al.   NATURE

Defective proviruses rapidly accumulate during acute HIV-1 infection

(2016) Katherine M Bruner et al.   NATURE MEDICINE

Defective HIV-1 proviruses produce novel protein-coding RNA species in HIV-infected patients on combination antiretroviral therapy

(2016) Hiromi Imamichi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Paired quantitative and qualitative assessment of the replication-competent HIV-1 reservoir and comparison with integrated proviral DNA

(2016) Julio C. C. Lorenzi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clonally expanded CD4+T cells can produce infectious HIV-1 in vivo

(2016) Francesco R. Simonetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultrasensitive single-genome sequencing: accurate, targeted, next generation sequencing of HIV-1 RNA

(2016) Valerie F. Boltz et al.   Retrovirology

HIV-1 Reservoirs During Suppressive Therapy

(2016) Kirston Barton et al.   TRENDS IN MICROBIOLOGY

Tissue reservoirs of HIV

(2016) Joseph K. Wong et al.   Current Opinion in HIV and AIDS

Initiation of antiretroviral therapy before detection of colonic infiltration by HIV reduces viral reservoirs, inflammation and immune activation

(2016) Trevor A Crowell et al.   Journal of the International AIDS Society

Establishment and stability of the latent HIV-1 DNA reservoir

(2016) Johanna Brodin et al.   eLife

HIV DNA Set Point is Rapidly Established in Acute HIV Infection and Dramatically Reduced by Early ART

(2016) Jintanat Ananworanich et al.   EBioMedicine

HIV-1 Integration Landscape during Latent and Active Infection

(2015) Lillian B. Cohn et al.   CELL

Longitudinal Genetic Characterization Reveals That Cell Proliferation Maintains a Persistent HIV Type 1 DNA Pool During Effective HIV Therapy

(2015) Susanne von Stockenstrom et al.   JOURNAL OF INFECTIOUS DISEASES

HIV reservoirs as obstacles and opportunities for an HIV cure

(2015) Tae-Wook Chun et al.   NATURE IMMUNOLOGY

Lifespan of effector memory CD4+ T cells determined by replication-incompetent integrated HIV-1 provirus

(2014) Hiromi Imamichi et al.   AIDS

Antiretroviral-Free HIV-1 Remission and Viral Rebound After Allogeneic Stem Cell Transplantation

(2014) Timothy J. Henrich et al.   ANNALS OF INTERNAL MEDICINE

Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues

(2014) Courtney V. Fletcher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection

(2014) T. A. Wagner et al.   SCIENCE

Specific HIV integration sites are linked to clonal expansion and persistence of infected cells

(2014) F. Maldarelli et al.   SCIENCE

Lack of Detectable HIV-1 Molecular Evolution during Suppressive Antiretroviral Therapy

(2014) Mary F. Kearney et al.   PLoS Pathogens

From reactivation of latent HIV-1 to elimination of the latent reservoir: The presence of multiple barriers to viral eradication

(2013) Liang Shan et al.   BIOESSAYS

Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure

(2013) Ya-Chi Ho et al.   CELL

Long-Term Reduction in Peripheral Blood HIV Type 1 Reservoirs Following Reduced-Intensity Conditioning Allogeneic Stem Cell Transplantation

(2013) T. J. Henrich et al.   JOURNAL OF INFECTIOUS DISEASES

HIV Populations Are Large and Accumulate High Genetic Diversity in a Nonlinear Fashion

(2013) F. Maldarelli et al.   JOURNAL OF VIROLOGY

The HIV-1 reservoir in eight patients on long-term suppressive antiretroviral therapy is stable with few genetic changes over time

(2013) L. Josefsson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIV-1 Reverse Transcription

(2013) W.-S. Hu et al.   Cold Spring Harbor Perspectives in Medicine

Challenges in Detecting HIV Persistence during Potentially Curative Interventions: A Study of the Berlin Patient

(2013) Steven A. Yukl et al.   PLoS Pathogens

Post-Treatment HIV-1 Controllers with a Long-Term Virological Remission after the Interruption of Early Initiated Antiretroviral Therapy ANRS VISCONTI Study

(2013) Asier Sáez-Cirión et al.   PLoS Pathogens

Lack of Compartmentalization of HIV-1 Quasispecies Between the Gut and Peripheral Blood Compartments

(2011) Hiromi Imamichi et al.   JOURNAL OF INFECTIOUS DISEASES

Long-Term Control of HIV byCCR5Delta32/Delta32 Stem-Cell Transplantation

(2009) Gero Hütter et al.   NEW ENGLAND JOURNAL OF MEDICINE

Human Immunodeficiency Virus Type 1 Population Genetics and Adaptation in Newly Infected Individuals

(2008) M. Kearney et al.   JOURNAL OF VIROLOGY

Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection

(2008) B. F. Keele et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA