Quantitative Structure Activity Relationship Studies and Molecular Dynamics Simulations of 2-(Aryloxyacetyl)cyclohexane-1,3-Diones Derivatives as 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors

Hydrophobicity-oriented drug design (HODD) of new human 4-hydroxyphenylpyruvate dioxygenase inhibitors

(2019) Ferdinand Ndikuryayo et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Molecular Insights into the Mechanism of 4-Hydroxyphenylpyruvate Dioxygenase Inhibition: Enzyme Kinetics, X-ray Crystallography and Computational Simulations

(2019) Hong-Yan Lin et al.   FEBS Journal

Design, Synthesis, and Herbicidal Activity Evaluation of Novel Aryl-Naphthyl Methanone Derivatives

(2019) Ying Fu et al.   Frontiers in Chemistry

Design, synthesis, SAR and molecular docking of novel green niacin-triketone HPPD inhibitor

(2019) Ying Fu et al.   INDUSTRIAL CROPS AND PRODUCTS

Combining molecular docking and QSAR studies for modeling the anti-tyrosinase activity of aromatic heterocycle thiosemicarbazone analogues

(2018) Huanhuan Dong et al.   JOURNAL OF MOLECULAR STRUCTURE

Inheritance of 4-hydroxyphenylpyruvate dioxygenase inhibitor herbicide resistance in an Amaranthus tuberculatus population from Iowa, USA

(2018) Daniel R. Kohlhase et al.   PLANT SCIENCE

Combination of Virtual Screening Protocol by in Silico toward the Discovery of Novel 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors

(2018) Ying Fu et al.   Frontiers in Chemistry

Herbicidal Activity and Molecular Docking Study of Novel ACCase Inhibitors

(2018) Fei Ye et al.   Frontiers in Plant Science

4-Hydroxyphenylpyruvate Dioxygenase Inhibitors: From Chemical Biology to Agrochemicals

(2017) Ferdinand Ndikuryayo et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

3D Pharmacophore-Based Virtual Screening and Docking Approaches toward the Discovery of Novel HPPD Inhibitors

(2017) Ying Fu et al.   MOLECULES

Structural basis of PROTAC cooperative recognition for selective protein degradation

(2017) Morgan S Gadd et al.   Nature Chemical Biology

Target-site resistance to acetolactate synthase (ALS)-inhibiting herbicides in Amaranthus palmeri from Argentina

(2017) Alvaro S Larran et al.   PEST MANAGEMENT SCIENCE

The different catalytic roles of the metal-binding ligands in human 4-hydroxyphenylpyruvate dioxygenase

(2016) C.-W. Huang et al.   BIOCHEMICAL JOURNAL

An Efficient One-Pot Synthesis of 2-(Aryloxyacetyl)cyclohexane-1,3-diones as Herbicidal 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors

(2016) Da-Wei Wang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Computational Study Exploring the Interaction Mechanism of Benzimidazole Derivatives as Potent Cattle Bovine Viral Diarrhea Virus Inhibitors

(2016) Jinghui Wang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Synthesis and Herbicidal Activity of Triketone–Quinoline Hybrids as Novel 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors

(2015) Da-Wei Wang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Molecular insight into the inhibition mechanism of plant and rat 4-hydroxyphenylpyruvate dioxygenase by molecular docking and DFT calculations

(2015) Telles Cardoso Silva et al.   MEDICINAL CHEMISTRY RESEARCH

Evaluation of Weed Management Programs and Response of FG72 Soybean to HPPD-Inhibiting Herbicides

(2015) John L. Schultz et al.   WEED TECHNOLOGY

Novel bacterial bioassay for a high-throughput screening of 4-hydroxyphenylpyruvate dioxygenase inhibitors

(2014) Emilie Rocaboy-Faquet et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Synthesis and Herbicidal Evaluation of Triketone-Containing Quinazoline-2,4-diones

(2014) Da-Wei Wang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Design, synthesis and herbicidal activity of novel quinazoline-2,4-diones as 4-hydroxyphenylpyruvate dioxygenase inhibitors

(2014) Da-Wei Wang et al.   PEST MANAGEMENT SCIENCE

4-Hydroxyphenylpyruvate dioxygenase and hydroxymandelate synthase: Exemplars of the α-keto acid dependent oxygenases

(2013) Graham R. Moran   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The Structure-Based Three-Dimensional Pharmacophore Models for Arabidopsis thaliana HPPD inhibitors as Herbicide

(2013) Jae Eun Cho et al.   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

Insight into the Structural Requirements of Protoporphyrinogen Oxidase Inhibitors: Molecular Docking and CoMFA of Diphenyl Ether, Isoxazole Phenyl, and Pyrazole Phenyl Ether

(2013) Shenggang Yang et al.   CHINESE JOURNAL OF CHEMISTRY

Taking into Account the Ion-Induced Dipole Interaction in the Nonbonded Model of Ions

(2013) Pengfei Li et al.   Journal of Chemical Theory and Computation

QSAR studies on diclofenac analogues as potent cyclooxygenase inhibitors using CoMFA and CoMSIA

(2013) K. Arvind et al.   MEDICINAL CHEMISTRY RESEARCH

Binding Site Analysis of CCR2 Through In Silico Methodologies: Docking, CoMFA, and CoMSIA

(2011) Gugan Kothandan et al.   Chemical Biology & Drug Design

4-Hydroxyphenylpyruvate Dioxygenase Catalysis

(2011) Corinne Raspail et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure–activity relationships of diphenyl-ether as protoporphyrinogen oxidase inhibitors: insights from computational simulations

(2011) Ge-Fei Hao et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Resistance to HPPD-inhibiting herbicides in a population of waterhemp (Amaranthus tuberculatus) from Illinois, United States

(2011) Nicholas E Hausman et al.   PEST MANAGEMENT SCIENCE

Why have no new herbicide modes of action appeared in recent years?

(2011) Stephen O Duke   PEST MANAGEMENT SCIENCE

Design, syntheses and 3D-QSAR studies of novel N-phenyl pyrrolidin-2-ones and N-phenyl-1H-pyrrol-2-ones as protoporphyrinogen oxidase inhibitors

(2010) Li Zhang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

HPPD: Ligand- and Target-Based Virtual Screening on a Herbicide Target

(2010) Miriam López-Ramos et al.   Journal of Chemical Information and Modeling

Structural Survey of Zinc-Containing Proteins and Development of the Zinc AMBER Force Field (ZAFF)

(2010) Martin B. Peters et al.   Journal of Chemical Theory and Computation

Herbicidal 4-hydroxyphenylpyruvate dioxygenase inhibitors—A review of the triketone chemistry story from a Syngenta perspective

(2009) Renaud Beaudegnies et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Docking and 3D QSAR studies of protoporphyrinogen oxidase inhibitor 3H-pyrazolo[3,4-d][1,2,3]triazin-4-one derivatives

(2009) Kunal Roy et al.   JOURNAL OF MOLECULAR MODELING