LPS Induces Preeclampsia-Like Phenotype in Rats and HTR8/SVneo Cells Dysfunction Through TLR4/p38 MAPK Pathway

Podocyte-specific Rac1 deficiency ameliorates podocyte damage and proteinuria in STZ-induced diabetic nephropathy in mice

(2018) Zhimei Lv et al.   Cell Death & Disease

Toll-like receptor-4/p38 MAPK signaling in the dorsal horn contributes to P2X4 receptor activation and BDNF over-secretion in cancer induced bone pain

(2017) Xiao-wen Meng et al.   NEUROSCIENCE RESEARCH

Rac1/β-Catenin Signalling Pathway Contributes to Trophoblast Cell Invasion by Targeting Snail and MMP9

(2016) Minghua Fan et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The role of inflammation in the pathology of preeclampsia

(2016) A. C. Harmon et al.   CLINICAL SCIENCE

Curcumin inhibits placental inflammation to ameliorate LPS-induced adverse pregnancy outcomes in mice via upregulation of phosphorylated Akt

(2016) Jianjun Zhou et al.   INFLAMMATION RESEARCH

Inflammatory processes are specifically enhanced in endothelial cells by placental-derived TNF-α: Implications in preeclampsia (PE)

(2016) Jeff Shaw et al.   PLACENTA

Preeclampsia

(2015) Jaimey M. Pauli et al.   OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA

Punicalagin Inhibits Inflammation in LPS-Induced RAW264.7 Macrophages via the Suppression of TLR4-Mediated MAPKs and NF-κB Activation

(2014) Xiaolong Xu et al.   INFLAMMATION

β-Arrestin 2 Negatively Regulates Toll-like Receptor 4 (TLR4)-triggered Inflammatory Signaling via Targeting p38 MAPK and Interleukin 10

(2014) Hui Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inflammation in rat pregnancy inhibits spiral artery remodeling leading to fetal growth restriction and features of preeclampsia

(2014) Tiziana Cotechini et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Blueberry-Enriched Diet Improves Renal Function and Reduces Oxidative Stress in Metabolic Syndrome Animals: Potential Mechanism of TLR4-MAPK Signaling Pathway

(2014) Anand R. Nair et al.   PLoS One

Podocyte Dedifferentiation: A Specialized Process for a Specialized Cell

(2014) Carl James May et al.   Frontiers in Endocrinology

Curcumin inhibits LPS-induced inflammation in rat vascular smooth muscle cells in vitro via ROS-relative TLR4-MAPK/NF-κB pathways

(2013) Zhe Meng et al.   ACTA PHARMACOLOGICA SINICA

A leading role for the immune system in the pathophysiology of preeclampsia

(2013) Estibalitz Laresgoiti-Servitje   JOURNAL OF LEUKOCYTE BIOLOGY

A review of the mechanism for poor placentation in early-onset preeclampsia: the role of autophagy in trophoblast invasion and vascular remodeling

(2013) Shigeru Saito et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Widespread DNA hypomethylation at gene enhancer regions in placentas associated with early-onset pre-eclampsia

(2013) J. D. Blair et al.   MOLECULAR HUMAN REPRODUCTION

A Critical Role for MAPK Signalling Pathways in the Transcriptional Regulation of Toll Like Receptors

(2013) Marylene Y. Peroval et al.   PLoS One

Calcitriol downregulates TNF-α and IL-6 expression in cultured placental cells from preeclamptic women

(2012) Nancy Noyola-Martínez et al.   CYTOKINE

Preeclampsia-associated stresses activate Gadd45a signaling and sFlt-1 in placental explants

(2012) Yali Xiong et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Dendritic cells in the circulation of women with preeclampsia demonstrate a pro-inflammatory bias secondary to dysregulation of TLR receptors

(2012) Britta Panda et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Oxidative Damage, Inflammation, and Toll-Like Receptor 4 Pathway Are Increased in Preeclamptic Patients: A Case-Control Study

(2012) Fabiana C. B. Bernardi et al.   Oxidative Medicine and Cellular Longevity

Magnesium sulfate reduces bacterial LPS-induced inflammation at the maternal–fetal interface

(2012) O. Dowling et al.   PLACENTA

A balancing act: mechanisms by which the fetus avoids rejection by the maternal immune system

(2011) J C Warning et al.   REPRODUCTION

Toll-Like Receptors at the Maternal-Fetal Interface in Normal Pregnancy and Pregnancy Disorders

(2010) Kaori Koga et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Changes in endovascular trophoblast invasion and spiral artery remodelling at term in a transgenic preeclamptic rat model

(2010) N. Geusens et al.   PLACENTA

New Insights into Epithelial-Mesenchymal Transition in Kidney Fibrosis

(2009) Y. Liu   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Epithelial-to-Mesenchymal Transition Is a Potential Pathway Leading to Podocyte Dysfunction and Proteinuria

(2008) Yingjian Li et al.   AMERICAN JOURNAL OF PATHOLOGY

p38MAPK inhibition attenuates LPS-induced acute lung injury involvement of NF-κB pathway

(2008) Su Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Cytokine Networks and the Regulation of Uterine Function in Pregnancy and Parturition

(2008) N. M. Orsi et al.   JOURNAL OF NEUROENDOCRINOLOGY

Pathophysiology of hypertension during preeclampsia: linking placental ischemia with endothelial dysfunction

(2007) Jeffrey S. Gilbert et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY