JNK Signaling Pathway Mediates Acetaminophen-Induced Hepatotoxicity Accompanied by Changes of Glutathione S-Transferase A1 Content and Expression

New insights into the role and mechanism of c-Jun-N-terminal kinase signaling in the pathobiology of liver diseases

(2018) Sanda Win et al.   HEPATOLOGY

Mechanisms of acetaminophen-induced liver injury and its implications for therapeutic interventions

(2018) Mingzhu Yan et al.   Redox Biology

Effects of C2-Ceramide and Oltipraz on Hepatocyte Nuclear Factor-1 and Glutathione S-Transferase A1 in Acetaminophen-Mediated Acute Mice Liver Injury

(2018) Xin Ma et al.   Frontiers in Pharmacology

Hepatoprotective effects of ethanol extracts from Folium Syringae against acetaminophen-induced hepatotoxicity in vitro and in vivo

(2017) Chen-Xi Shi et al.   Journal of the Chinese Medical Association

Apoptosis-inducing factor (AIF) nuclear translocation mediated caspase-independent mechanism involves in X-ray-induced MCF-7 cell death

(2016) Shana Yang et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Chitohexaose protects against acetaminophen-induced hepatotoxicity in mice

(2016) P K Barman et al.   Cell Death & Disease

Adenosine 5′-monophosphate blocks acetaminophen toxicity by increasing ubiquitination-mediated ASK1 degradation

(2016) Xiao Yang et al.   Oncotarget

The impact of partial hepatectomy on oxidative state in the liver remnant – An in vivo swine model

(2016) Åse Florholmen-Kjær et al.   Redox Biology

NADPH oxidase 4 regulates homocysteine metabolism and protects against acetaminophen-induced liver damage in mice

(2015) Thomas V.A. Murray et al.   FREE RADICAL BIOLOGY AND MEDICINE

Low Dose Acetaminophen Induces Reversible Mitochondrial Dysfunction Associated with Transient c-Jun N-Terminal Kinase Activation in Mouse Liver

(2015) Jiangting Hu et al.   TOXICOLOGICAL SCIENCES

Glutathione S-transferase A1 (GSTA1) release, an early indicator of acute hepatic injury in mice

(2014) Fangping Liu et al.   FOOD AND CHEMICAL TOXICOLOGY

Activator protein 1 transcription factor fos-related antigen 1 (fra-1) is dispensable for murine liver fibrosis, but modulates xenobiotic metabolism

(2013) Sebastian C. Hasenfuss et al.   HEPATOLOGY

Acute Liver Failure

(2013) William Bernal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: Lessons learned from acetaminophen hepatotoxicity

(2012) Hartmut Jaeschke et al.   DRUG METABOLISM REVIEWS

Peroxisome proliferator-activated receptor alpha induction of uncoupling protein 2 protects against acetaminophen-induced liver toxicity

(2012) Andrew D. Patterson et al.   HEPATOLOGY

The effect of menadione on glutathione S-transferase A1 (GSTA1): c-Jun N-terminal kinase (JNK) complex dissociation in human colonic adenocarcinoma Caco-2 cells

(2012) Humaira Adnan et al.   TOXICOLOGY LETTERS

Protective effects of seabuckthorn (Hippophae rhamnoides L.) seed oil against carbon tetrachloride-induced hepatotoxicity in mice

(2009) Yu-Wen Hsu et al.   FOOD AND CHEMICAL TOXICOLOGY

Inhibition of c-Jun NH2-terminal kinase switches Smad3 signaling from oncogenesis to tumor- suppression in rat hepatocellular carcinoma

(2009) Hiromitsu Nagata et al.   HEPATOLOGY

Protection of acetaminophen induced mitochondrial dysfunctions and hepatic necrosis via Akt-NF-κB pathway: Role of a novel plant protein

(2008) Ayantika Ghosh et al.   CHEMICO-BIOLOGICAL INTERACTIONS