3-(2-Oxo-2-phenylethylidene)-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-one (compound 1), a novel potent Nrf2/ARE inducer, protects against DSS-induced colitis via inhibiting NLRP3 inflammasome

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Title
3-(2-Oxo-2-phenylethylidene)-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-one (compound 1), a novel potent Nrf2/ARE inducer, protects against DSS-induced colitis via inhibiting NLRP3 inflammasome
Authors
Keywords
Nrf2, NLRP3 inflammasome, DSS, Inflammatory bowel disease, ROS
Journal
BIOCHEMICAL PHARMACOLOGY
Volume 101, Issue -, Pages 71-86
Publisher
Elsevier BV
Online
2015-11-14
DOI
10.1016/j.bcp.2015.11.015

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