Rice Seeds as Biofactories of Rationally Designed and Cell-Penetrating Antifungal PAF Peptides

Worldwide emergence of resistance to antifungal drugs challenges human health and food security

(2018) Matthew C. Fisher et al.   SCIENCE

An overview on the strategies to exploit rice endosperm as production platform for biopharmaceuticals

(2017) Fumio Takaiwa et al.   PLANT SCIENCE

Antimicrobial peptides

(2016) Ling-juan Zhang et al.   CURRENT BIOLOGY

“Is there an emerging need for new antifungals?”

(2016) John R. Perfect   EXPERT OPINION ON EMERGING DRUGS

Production of Biologically Active Cecropin A Peptide in Rice Seed Oil Bodies

(2016) Laura Montesinos et al.   PLoS One

Concatemerization increases the inhibitory activity of short, cell-penetrating, cationic and tryptophan-rich antifungal peptides

(2015) Belén López-García et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Crop-destroying fungal and oomycete pathogens challenge food security

(2015) Daniel P. Bebber et al.   FUNGAL GENETICS AND BIOLOGY

Production of cecropin A antimicrobial peptide in rice seed endosperm

(2014) Mireia Bundó et al.   BMC PLANT BIOLOGY

Immobilization of Clostridium cellulolyticum d-Psicose 3-Epimerase on Artificial Oil Bodies

(2014) Chih-Wen Tseng et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Transgenic Rice Seeds Accumulating Recombinant Hypoallergenic Birch Pollen Allergen Bet v 1 Generate Giant Protein Bodies

(2013) Shuyi Wang et al.   PLANT AND CELL PHYSIOLOGY

The production of recombinant cationic α-helical antimicrobial peptides in plant cells induces the formation of protein bodies derived from the endoplasmic reticulum

(2013) Nuri Company et al.   PLANT BIOTECHNOLOGY JOURNAL

Using storage organelles for the accumulation and encapsulation of recombinant proteins

(2012) Imran Khan et al.   Biotechnology Journal

Constitutive expression of transgenes encoding derivatives of the synthetic antimicrobial peptide BP100: impact on rice host plant fitness

(2012) Anna Nadal et al.   BMC PLANT BIOLOGY

Emerging fungal threats to animal, plant and ecosystem health

(2012) Matthew C. Fisher et al.   NATURE

Hidden Killers: Human Fungal Infections

(2012) G. D. Brown et al.   Science Translational Medicine

Understanding the mechanism of action of cell-penetrating antifungal peptides using the rationally designed hexapeptide PAF26 as a model

(2012) Alberto Muñoz et al.   Fungal Biology Reviews

Prevention of allergic asthma by vaccination with transgenic rice seed expressing mite allergen: induction of allergen-specific oral tolerance without bystander suppression

(2011) Kazuya Suzuki et al.   PLANT BIOTECHNOLOGY JOURNAL

The formation, function and fate of protein storage compartments in seeds

(2011) Verena Ibl et al.   PROTOPLASMA

Rice seed ER-derived protein body as an efficient delivery vehicle for oral tolerogenic peptides

(2010) Hidenori Takagi et al.   PEPTIDES

Antihypertensive activity of transgenic rice seed containing an 18-repeat novokinin peptide localized in the nucleolus of endosperm cells

(2010) Yuhya Wakasa et al.   PLANT BIOTECHNOLOGY JOURNAL

Seed-based expression systems for plant molecular farming

(2010) Joseph Boothe et al.   PLANT BIOTECHNOLOGY JOURNAL

Expression and recovery of biologically active recombinant Apolipoprotein AIMilano from transgenic safflower (Carthamus tinctorius) seeds

(2010) Cory L. Nykiforuk et al.   PLANT BIOTECHNOLOGY JOURNAL

Immobilization of Neocallimastix patriciarum xylanase on artificial oil bodies and statistical optimization of enzyme activity

(2008) Ying-Jing Hung et al.   BIORESOURCE TECHNOLOGY

Efficient induction of oral tolerance by fusing cholera toxin B subunit with allergen-specific T-cell epitopes accumulated in rice seed

(2008) Hidenori Takagi et al.   VACCINE