Comprehensive Characterization of the Attenuated Double Auxotroph Mycobacterium tuberculosisΔleuDΔpanCD as an Alternative to H37Rv

Rational Design of Biosafety Level 2-Approved, Multidrug-Resistant Strains of Mycobacterium tuberculosis through Nutrient Auxotrophy

(2018) Catherine Vilchèze et al.   mBio

Differential DNA methylation of potassium channel KCa3.1 and immune signalling pathways is associated with infant immune responses following BCG vaccination

(2018) Mateusz Hasso-Agopsowicz et al.   Scientific Reports

Age-related waning of immune responses to BCG in healthy children supports the need for a booster dose of BCG in TB endemic countries

(2018) Elizabeth Whittaker et al.   Scientific Reports

Proteogenomic Investigation of Strain Variation in Clinical Mycobacterium tuberculosis Isolates

(2017) Tiaan Heunis et al.   JOURNAL OF PROTEOME RESEARCH

An attenuated quadruple gene mutant of Mycobacterium tuberculosis imparts protection against tuberculosis in guinea pigs

(2017) Ritika Kar Bahal et al.   Biology Open

bioA mutant of Mycobacterium tuberculosis shows severe growth defect and imparts protection against tuberculosis in guinea pigs

(2017) Ritika Kar et al.   PLoS One

An attenuated Mycobacterium tuberculosis clinical strain with a defect in ESX-1 secretion induces minimal host immune responses and pathology

(2017) Helena Strand Clemmensen et al.   Scientific Reports

Elucidating population-wide mycobacterial replication dynamics at the single-cell level

(2016) Jacoba M. Mouton et al.   MICROBIOLOGY-SGM

Whole genome sequence analysis of Mycobacterium suricattae

(2015) Anzaan Dippenaar et al.   TUBERCULOSIS

Dormancy Associated Translation Inhibitor (DATIN/Rv0079) of Mycobacterium tuberculosis interacts with TLR2 and induces proinflammatory cytokine expression

(2013) Ashutosh Kumar et al.   CYTOKINE

Low Induction of Proinflammatory Cytokines Parallels Evolutionary Success of Modern Strains within the Mycobacterium tuberculosis Beijing Genotype

(2013) Arjan van Laarhoven et al.   INFECTION AND IMMUNITY

Streptomycin-Starved Mycobacterium tuberculosis 18b, a Drug Discovery Tool for Latent Tuberculosis

(2012) Ming Zhang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

DELLY: structural variant discovery by integrated paired-end and split-read analysis

(2012) T. Rausch et al.   BIOINFORMATICS

Function Prediction of Rv0079, A HypotheticalMycobacterium tuberculosisDosR Regulon Protein

(2012) Seema Mishra   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Mycobacterium tuberculosis DosR Regulon Gene Rv0079 Encodes a Putative, ‘Dormancy Associated Translation Inhibitor (DATIN)’

(2012) Ashutosh Kumar et al.   PLoS One

Extended safety and efficacy studies of a live attenuated double leucine and pantothenate auxotroph of Mycobacterium tuberculosis as a vaccine candidate

(2011) Samantha L. Sampson et al.   VACCINE

Human Macrophage Responses to Clinical Isolates from the Mycobacterium tuberculosis Complex Discriminate between Ancient and Modern Lineages

(2011) Damien Portevin et al.   PLoS Pathogens

Variation among Genome Sequences of H37Rv Strains of Mycobacterium tuberculosis from Multiple Laboratories

(2010) T. R. Ioerger et al.   JOURNAL OF BACTERIOLOGY

Essentiality and functional analysis of type I and type III pantothenate kinases of Mycobacterium tuberculosis

(2010) D. Awasthy et al.   MICROBIOLOGY-SGM

Optimisation of Bioluminescent Reporters for Use with Mycobacteria

(2010) Nuria Andreu et al.   PLoS One

Innate Immune Response to Mycobacterium tuberculosis Beijing and Other Genotypes

(2010) Chongzhen Wang et al.   PLoS One

The Mycobacterium tuberculosis DosR Regulon Assists in Metabolic Homeostasis and Enables Rapid Recovery from Nonrespiring Dormancy

(2009) R. L. Leistikow et al.   JOURNAL OF BACTERIOLOGY

Quantitative Drug Susceptibility Testing of Mycobacterium tuberculosis by Use of MGIT 960 and EpiCenter Instrumentation

(2009) B. Springer et al.   JOURNAL OF CLINICAL MICROBIOLOGY

A replication clock for Mycobacterium tuberculosis

(2009) Wendy P Gill et al.   NATURE MEDICINE

Universal sample preparation method for proteome analysis

(2009) Jacek R Wiśniewski et al.   NATURE METHODS

Mycobacterium tuberculosis Senses Host-Derived Carbon Monoxide during Macrophage Infection

(2008) Michael U. Shiloh et al.   Cell Host & Microbe

Heme Oxygenase-1-derived Carbon Monoxide Induces theMycobacterium tuberculosisDormancy Regulon

(2008) Ashwani Kumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Construction of a severely attenuated mutant of Mycobacterium tuberculosis for reducing risk to laboratory workers

(2008) Farahnaz Movahedzadeh et al.   TUBERCULOSIS