The ER membrane protein complex is required to ensure correct topology and stable expression of flavivirus polyproteins

Differential and convergent utilization of autophagy components by positive-strand RNA viruses

(2019) Emma Abernathy et al.   PLOS BIOLOGY

A network of chaperones prevents and detects failures in membrane protein lipid bilayer integration

(2019) João P. L. Coelho et al.   Nature Communications

The Role of EMC during Membrane Protein Biogenesis

(2019) Patrick J. Chitwood et al.   TRENDS IN CELL BIOLOGY

The ER Membrane Protein Complex Promotes Biogenesis of Dengue and Zika Virus Non-structural Multi-pass Transmembrane Proteins to Support Infection

(2019) David L. Lin et al.   Cell Reports

A novel interaction between dengue virus nonstructural protein 1 and the NS4A-2K-4B precursor is required for viral RNA replication but not for formation of the membranous replication organelle

(2019) Anna Płaszczyca et al.   PLoS Pathogens

Dengue Virus Selectively Annexes Endoplasmic Reticulum-Associated Translation Machinery as a Strategy for Co-opting Host Cell Protein Synthesis

(2018) David W. Reid et al.   JOURNAL OF VIROLOGY

Rewiring cellular networks by members of the Flaviviridae family

(2018) Christopher J. Neufeldt et al.   NATURE REVIEWS MICROBIOLOGY

Dengue virus-induced ER stress is required for autophagy activation, viral replication, and pathogenesis both in vitro and in vivo

(2018) Ying-Ray Lee et al.   Scientific Reports

The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins

(2018) Matthew J Shurtleff et al.   eLife

EMC Is Required to Initiate Accurate Membrane Protein Topogenesis

(2018) Patrick J. Chitwood et al.   CELL

The ER membrane protein complex promotes biogenesis of sterol-related enzymes maintaining cholesterol homeostasis

(2018) Norbert Volkmar et al.   JOURNAL OF CELL SCIENCE

The ER membrane protein complex is a transmembrane domain insertase

(2017) Alina Guna et al.   SCIENCE

A Small-Molecule Oligosaccharyltransferase Inhibitor with Pan-flaviviral Activity

(2017) Andreas S. Puschnik et al.   Cell Reports

A CRISPR screen defines a signal peptide processing pathway required by flaviviruses

(2016) Rong Zhang et al.   NATURE

Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screens

(2016) Caleb D. Marceau et al.   NATURE

Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics

(2016) George Savidis et al.   Cell Reports

The search for nucleoside/nucleotide analog inhibitors of dengue virus

(2015) Yen-Liang Chen et al.   ANTIVIRAL RESEARCH

Mapping the Interactions between the NS4B and NS3 Proteins of Dengue Virus

(2015) Jing Zou et al.   JOURNAL OF VIROLOGY

UPR, autophagy, and mitochondria crosstalk underlies the ER stress response

(2015) Daniela Senft et al.   TRENDS IN BIOCHEMICAL SCIENCES

A CRISPR-Based Screen Identifies Genes Essential for West-Nile-Virus-Induced Cell Death

(2015) Hongming Ma et al.   Cell Reports

Easy quantitative assessment of genome editing by sequence trace decomposition

(2014) Eva K. Brinkman et al.   NUCLEIC ACIDS RESEARCH

Ribavirin: a drug active against many viruses with multiple effects on virus replication and propagation. Molecular basis of ribavirin resistance

(2014) Stéphanie Beaucourt et al.   Current Opinion in Virology

The Mammalian Endoplasmic Reticulum-Associated Degradation System

(2012) J. A. Olzmann et al.   Cold Spring Harbor Perspectives in Biology

Membrane Protein Insertion at the Endoplasmic Reticulum

(2011) Sichen Shao et al.   Annual Review of Cell and Developmental Biology

Dengue Virus Modulates the Unfolded Protein Response in a Time-dependent Manner

(2011) José Peña et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Defining human ERAD networks through an integrative mapping strategy

(2011) John C. Christianson et al.   NATURE CELL BIOLOGY

Discovery of insect and human dengue virus host factors

(2009) October M. Sessions et al.   NATURE

Comprehensive Characterization of Genes Required for Protein Folding in the Endoplasmic Reticulum

(2009) M. C. Jonikas et al.   SCIENCE

Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling

(2009) N. T. Ingolia et al.   SCIENCE

RNA interference screen for human genes associated with West Nile virus infection

(2008) Manoj N. Krishnan et al.   NATURE