Role of Leptin Deficiency, Inefficiency, and Leptin Receptors in Obesity

Novel Leptin Receptor Mutations Identified in Two Girls with Severe Obesity Are Associated with Increased Bone Mineral Density

(2016) Sabine E. Hannema et al.   Hormone Research in Paediatrics

Persistent Chromatin Modifications Induced by High Fat Diet

(2016) Amy Leung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An assessment of molecular pathways of obesity susceptible to nutrient, toxicant and genetically induced epigenetic perturbation

(2016) Jing Xue et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Severe Early-Onset Obesity Due to Bioinactive Leptin Caused by a p.N103K Mutation in the Leptin Gene

(2015) Martin Wabitsch et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

Leptin Therapy Alters Appetite and Neural Responses to Food Stimuli in Brain Areas of Leptin-Sensitive Subjects Without Altering Brain Structure

(2014) Olivia M. Farr et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Imbalance between Neutrophil Elastase and its Inhibitor α1-Antitrypsin in Obesity Alters Insulin Sensitivity, Inflammation, and Energy Expenditure

(2013) Virginie Mansuy-Aubert et al.   Cell Metabolism

A novel mutation of the leptin gene in an Indian patient

(2013) S. Thakur et al.   CLINICAL GENETICS

NovelLEPRmutations in obese Pakistani children identified by PCR-based enrichment and next generation sequencing

(2013) Sadia Saeed et al.   Obesity

Long-Term Stabilization Effects of Leptin on Brain Functions in a Leptin-Deficient Patient

(2013) Sabine Frank et al.   PLoS One

Leptin and leptin receptor-related monogenic obesity

(2012) Beatrice Dubern et al.   BIOCHIMIE

High prevalence of leptin and melanocortin-4 receptor gene mutations in children with severe obesity from Pakistani consanguineous families

(2012) Sadia Saeed et al.   MOLECULAR GENETICS AND METABOLISM

Congenital leptin deficiency: diagnosis and effects of leptin replacement therapy

(2011) Gilberto Paz-Filho et al.   Arquivos Brasileiros de Endocrinologia e Metabologia

Leptin deficiency andleptingene mutations in obese children from Pakistan

(2011) Warda Fatima et al.   International Journal of Pediatric Obesity

Homozygosity for a novel missense mutation in the leptin receptor gene (P316T) in two Egyptian cousins with severe early onset obesity

(2011) I. Mazen et al.   MOLECULAR GENETICS AND METABOLISM

Ten years of leptin replacement therapy

(2011) G. Paz-Filho et al.   Obesity Reviews

A New Missense Mutation in the Leptin Gene Causes Mild Obesity and Hypogonadism without Affecting T Cell Responsiveness

(2010) Pamela Fischer-Posovszky et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

A tale of two hormones

(2010) Jeffrey M Friedman   NATURE MEDICINE

Leptin in humans: lessons from translational research

(2009) Susann Blüher et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Obesity, airway hyperresponsiveness, and inflammation

(2009) Stephanie A. Shore   JOURNAL OF APPLIED PHYSIOLOGY

A novel homozygous missense mutation of the leptin gene (N103K) in an obese Egyptian patient

(2009) I. Mazen et al.   MOLECULAR GENETICS AND METABOLISM