The Cadherin Cry1Ac Binding-Region is Necessary for the Cooperative Effect with ABCC2 Transporter Enhancing Insecticidal Activity of Bacillus thuringiensis Cry1Ac Toxin

The intracellular region of silkworm cadherin-like protein is not necessary to mediate the toxicity of Bacillus thuringiensis Cry1Aa and Cry1Ab toxins

(2018) Haruka Endo et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

A single amino acid polymorphism in ABCC2 loop 1 is responsible for differential toxicity of Bacillus thuringiensis Cry1Ac toxin in different Spodoptera (Noctuidae) species

(2018) Leilei Liu et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Role of Bacillus thuringiensis Cry1A toxins domains in the binding to the ABCC2 receptor from Spodoptera exigua

(2018) María Martínez-Solís et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Intra- and extracellular domains of the Helicoverpa armigera cadherin mediate Cry1Ac cytotoxicity

(2017) Haonan Zhang et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Cytotoxicity and binding profiles of activated Cry1Ac and Cry2Ab to three insect cell lines

(2017) Jizhen Wei et al.   Insect Science

A Single Point Mutation Resulting in Cadherin Mislocalization Underpins Resistance againstBacillus thuringiensisToxin in Cotton Bollworm

(2017) Yutao Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Probing the Single Key Amino Acid Responsible for the Novel Catalytic Function of ent-Kaurene Oxidase Supported by NADPH-Cytochrome P450 Reductases in Tripterygium wilfordii

(2017) Ping Su et al.   Frontiers in Plant Science

ABCC2 is associated with Bacillus thuringiensis Cry1Ac toxin oligomerization and membrane insertion in diamondback moth

(2017) Josue Ocelotl et al.   Scientific Reports

Functional characterization ofBacillus thuringiensisCry toxin receptors explains resistance in insects

(2016) Shiho Tanaka et al.   FEBS Journal

Three toxins, two receptors, one mechanism: Mode of action of Cry1A toxins from Bacillus thuringiensis in Heliothis virescens

(2016) Anne Bretschneider et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

TheSpodoptera exigua(Lepidoptera: Noctuidae) ABCC2 Mediates Cry1Ac Cytotoxicity and, in Conjunction with Cadherin, Contributes to Enhance Cry1Ca Toxicity in Sf9 Cells

(2016) Xiang-Liang Ren et al.   JOURNAL OF ECONOMIC ENTOMOLOGY

Single amino acid insertions in extracellular loop 2 of Bombyx mori ABCC2 disrupt its receptor function for Bacillus thuringiensis Cry1Ab and Cry1Ac but not Cry1Aa toxins

(2016) Shiho Tanaka et al.   PEPTIDES

Resistance to Bacillus thuringiensis Mediated by an ABC Transporter Mutation Increases Susceptibility to Toxins from Other Bacteria in an Invasive Insect

(2016) Yutao Xiao et al.   PLoS Pathogens

Endogenous expression of a Bt toxin receptor in the Cry1Ac-susceptible insect cell line and its synergistic effect with cadherin on cytotoxicity of activated Cry1Ac

(2015) Zuwen Chen et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Expression of recombinant and mosaic Cry1Ac receptors from Helicoverpa armigera and their influences on the cytotoxicity of activated Cry1Ac to Spodoptera litura Sl-HP cells

(2014) Peng Xu et al.   CYTOTECHNOLOGY

Large-scale test of the natural refuge strategy for delaying insect resistance to transgenic Bt crops

(2014) Lin Jin et al.   NATURE BIOTECHNOLOGY

The ATP-binding cassette transporter subfamily C member 2 inBombyx morilarvae is a functional receptor for Cry toxins fromBacillus thuringiensis

(2013) Shiho Tanaka et al.   FEBS Journal

Widespread adoption of Bt cotton and insecticide decrease promotes biocontrol services

(2012) Yanhui Lu et al.   NATURE

Learning the ABCs of Bt: ABC transporters and insect resistance to Bacillus thuringiensis provide clues to a crucial step in toxin mode of action

(2012) David G. Heckel   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Non-Recessive Bt Toxin Resistance Conferred by an Intracellular Cadherin Mutation in Field-Selected Populations of Cotton Bollworm

(2012) Haonan Zhang et al.   PLoS One

Differential Protection of Cry1Fa Toxin against Spodoptera frugiperda Larval Gut Proteases by Cadherin Orthologs Correlates with Increased Synergism

(2011) Khalidur Rahman et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Bacillus thuringiensis: A story of a successful bioinsecticide

(2011) Alejandra Bravo et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Diverse cadherin mutations conferring resistance to Bacillus thuringiensis toxin Cry1Ac in Helicoverpa armigera

(2010) Jing Zhao et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Role of Alkaline Phosphatase fromManduca sextain the Mechanism of Action ofBacillus thuringiensisCry1Ab Toxin

(2010) Iván Arenas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An ABC Transporter Mutation Is Correlated with Insect Resistance to Bacillus thuringiensis Cry1Ac Toxin

(2010) Linda J. Gahan et al.   PLoS Genetics

Helicoverpa armigera cadherin fragment enhances Cry1Ac insecticidal activity by facilitating toxin-oligomer formation

(2009) Donghai Peng et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Manduca sexta(Lepidoptera: Sphingidae) cadherin fragments function as synergists for Cry1A and Cry1CBacillus thuringiensistoxins against noctuid mothsHelicoverpa zea, Agrotis ipsilonandSpodoptera exigua

(2009) Mohd Amir F Abdullah et al.   PEST MANAGEMENT SCIENCE

Enhancement of insecticidal activity of Bacillus thuringiensis Cry1A toxins by fragments of a toxin-binding cadherin correlates with oligomer formation

(2008) Sabino Pacheco et al.   PEPTIDES