Cancer cell population growth kinetics at low densities deviate from the exponential growth model and suggest an Allee effect

Fibroblasts and alectinib switch the evolutionary games played by non-small cell lung cancer

(2019) Artem Kaznatcheev et al.   Nature Ecology & Evolution

Cancer as a Social Dysfunction—Why Cancer Research Needs New Thinking

(2018) Robert Axelrod et al.   MOLECULAR CANCER RESEARCH

Precision Medicine with Imprecise Therapy: Computational Modeling for Chemotherapy in Breast Cancer

(2018) Matthew T. McKenna et al.   Translational Oncology

A Hierarchical, Data-Driven Approach to Modeling Single-Cell Populations Predicts Latent Causes of Cell-To-Cell Variability

(2018) Carolin Loos et al.   Cell Systems

The Optimal Radiation Dose to Induce Robust Systemic Anti-Tumor Immunity

(2018) Jan Poleszczuk et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Analysis of Single-Cell RNA-Seq Identifies Cell-Cell Communication Associated with Tumor Characteristics

(2018) Manu P. Kumar et al.   Cell Reports

Extinction rates in tumour public goods games

(2017) Philip Gerlee et al.   Journal of the Royal Society Interface

Epithelial/mesenchymal plasticity: how have quantitative mathematical models helped improve our understanding?

(2017) Mohit Kumar Jolly et al.   Molecular Oncology

Multi-scale Modeling in Clinical Oncology: Opportunities and Barriers to Success

(2016) Thomas E. Yankeelov et al.   ANNALS OF BIOMEDICAL ENGINEERING

Feedback Regulation in a Cancer Stem Cell Model can Cause an Allee Effect

(2016) Anna Konstorum et al.   BULLETIN OF MATHEMATICAL BIOLOGY

Ecological paradigms to understand the dynamics of metastasis

(2016) Sarah R. Amend et al.   CANCER LETTERS

Mathematical Modeling Reveals That Changes to Local Cell Density Dynamically Modulate Baseline Variations in Cell Growth and Drug Response

(2016) J. M. Greene et al.   CANCER RESEARCH

Influences of Allee effects in the spreading of malignant tumours

(2016) Lotte Sewalt et al.   JOURNAL OF THEORETICAL BIOLOGY

Selection, calibration, and validation of models of tumor growth

(2016) E. A. B. F. Lima et al.   MATHEMATICAL MODELS & METHODS IN APPLIED SCIENCES

Rapid emergence and mechanisms of resistance by U87 glioblastoma cells to doxorubicin in an in vitro tumor microfluidic ecology

(2016) Jeonghun Han et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Systematic Approach to Determining the Identifiability of Multistage Carcinogenesis Models

(2016) Andrew F. Brouwer et al.   RISK ANALYSIS

The effects of demographic stochasticity and parameter uncertainty on predicting the establishment of introduced species

(2016) Gian Marco Palamara et al.   Ecology and Evolution

Inference for Stochastic Chemical Kinetics Using Moment Equations and System Size Expansion

(2016) Fabian Fröhlich et al.   PLoS Computational Biology

Optimized Sleeping Beauty transposons rapidly generate stable transgenic cell lines

(2015) Eric Kowarz et al.   Biotechnology Journal

Non-genetic cancer cell plasticity and therapy-induced stemness in tumour relapse: ‘What does not kill me strengthens me’

(2015) A O Pisco et al.   BRITISH JOURNAL OF CANCER

Identifiability Results for Several Classes of Linear Compartment Models

(2015) Nicolette Meshkat et al.   BULLETIN OF MATHEMATICAL BIOLOGY

Models for Allee effect based on physical principles

(2015) Renato Vieira dos Santos et al.   JOURNAL OF THEORETICAL BIOLOGY

Heterogeneity for IGF-II production maintained by public goods dynamics in neuroendocrine pancreatic cancer

(2015) Marco Archetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ecology meets cancer biology: the cancer swamp promotes the lethal cancer phenotype

(2015) Sarah R. Amend et al.   Oncotarget

Optimized Sleeping Beauty transposons rapidly generate stable transgenic cell lines

(2015) Eric Kowarz et al.   Biotechnology Journal

Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers

(2014) Allison S. Cleary et al.   NATURE

Non-cell-autonomous driving of tumour growth supports sub-clonal heterogeneity

(2014) Andriy Marusyk et al.   NATURE

Ecological Therapy for Cancer: Defining Tumors Using an Ecosystem Paradigm Suggests New Opportunities for Novel Cancer Treatments

(2014) Kenneth J. Pienta et al.   Translational Oncology

Quantifying invasion risk: the relationship between establishment probability and founding population size

(2014) Richard P. Duncan et al.   Methods in Ecology and Evolution

Classical Mathematical Models for Description and Prediction of Experimental Tumor Growth

(2014) Sébastien Benzekry et al.   PLoS Computational Biology

Tumor growth dynamics: insights into evolutionary processes

(2013) Ignacio A. Rodriguez-Brenes et al.   TRENDS IN ECOLOGY & EVOLUTION

Exploiting ecological principles to better understand cancer progression and treatment

(2013) D. Basanta et al.   Interface Focus

Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells

(2011) Piyush B. Gupta et al.   CELL

Paracrine and Autocrine Signals Induce and Maintain Mesenchymal and Stem Cell States in the Breast

(2011) Christina Scheel et al.   CELL

Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice

(2011) Dipak Panigrahy et al.   JOURNAL OF CLINICAL INVESTIGATION

Lack of confidence in approximate Bayesian computation model choice

(2011) C. P. Robert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural and practical identifiability analysis of partially observed dynamical models by exploiting the profile likelihood

(2009) A. Raue et al.   BIOINFORMATICS

Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates

(2009) Lajos Mátés et al.   NATURE GENETICS

Non-genetic heterogeneity — a mutation-independent driving force for the somatic evolution of tumours

(2009) Amy Brock et al.   NATURE REVIEWS GENETICS

Stem cell transcriptome profiling via massive-scale mRNA sequencing

(2008) Nicole Cloonan et al.   NATURE METHODS