Development and characterization of an enterovirus 71 (EV71) virus-like particles (VLPs) vaccine produced in Pichia pastoris

Five-year immunity persistence following immunization with inactivated enterovirus 71 type (EV71) vaccine in healthy children: A further observation

(2018) Yuemei Hu et al.   Human Vaccines & Immunotherapeutics

A virus-like particle-based tetravalent vaccine for hand, foot, and mouth disease elicits broad and balanced protective immunity

(2018) Wei Zhang et al.   Emerging Microbes & Infections

Non-clinical safety assessment of repeated intramuscular administration of an EV-A71 VLP vaccine in rabbits

(2018) Brian Salmons et al.   VACCINE

Optimizing the utilization of aluminum adjuvants in vaccines: you might just get what you want

(2018) Harm HogenEsch et al.   npj Vaccines

2-Year Efficacy, Immunogenicity, and Safety of Vigoo Enterovirus 71 Vaccine in Healthy Chinese Children: A Randomized Open-Label Study

(2016) Mingwei Wei et al.   JOURNAL OF INFECTIOUS DISEASES

Characterizing Enterovirus 71 and Coxsackievirus A16 virus-like particles production in insect cells

(2016) Balaji Somasundaram et al.   METHODS

The Epidemiology of Hand, Foot and Mouth Disease in Asia

(2016) Wee Ming Koh et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Comprehensive safety assessment of a human inactivated diploid enterovirus 71 vaccine based on a phase III clinical trial

(2016) Wei Zhang et al.   Human Vaccines & Immunotherapeutics

The Current Status of the Disease Caused by Enterovirus 71 Infections: Epidemiology, Pathogenesis, Molecular Epidemiology, and Vaccine Development

(2016) Ping-Chin Chang et al.   International Journal of Environmental Research and Public Health

EV-A71 vaccine licensure: a first step for multivalent enterovirus vaccine to control HFMD and other severe diseases

(2016) Qunying Mao et al.   Emerging Microbes & Infections

Immunity and clinical efficacy of an inactivated enterovirus 71 vaccine in healthy Chinese children: a report of further observations

(2015) Longding Liu et al.   BMC Medicine

Development of EV71 virus-like particle purification processes

(2015) Shih-Yeh Lin et al.   VACCINE

Immunogenicity and performance of an enterovirus 71 virus-like-particle vaccine in nonhuman primates

(2015) Pei-Yin Lim et al.   VACCINE

High-yield production of recombinant virus-like particles of enterovirus 71 in Pichia pastoris and their protective efficacy against oral viral challenge in mice

(2015) Chao Zhang et al.   VACCINE

Strategies to guide the antibody affinity maturation process

(2015) Nicole A Doria-Rose et al.   Current Opinion in Virology

Immunogenicity and protective efficacy of an EV71 virus-like particle vaccine against lethal challenge in newborn mice

(2015) Shiyang Sun et al.   Human Vaccines & Immunotherapeutics

Disease burden of enterovirus 71 in rural central China: A community-based survey

(2015) Zheng-kai Gan et al.   Human Vaccines & Immunotherapeutics

Advances in aluminum hydroxide-based adjuvant research and its mechanism

(2015) Peng He et al.   Human Vaccines & Immunotherapeutics

Protein expression in Pichia pastoris: recent achievements and perspectives for heterologous protein production

(2014) Mudassar Ahmad et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

A virus-like particle based bivalent vaccine confers dual protection against enterovirus 71 and coxsackievirus A16 infections in mice

(2014) Zhiqiang Ku et al.   VACCINE

Clinical evaluation for batch consistency of an inactivated enterovirus 71 vaccine in a large-scale phase 3 clinical trial

(2014) Yi-Juan Chen et al.   Human Vaccines & Immunotherapeutics

Neutralizing Antibodies Induced by Recombinant Virus-Like Particles of Enterovirus 71 Genotype C4 Inhibit Infection at Pre- and Post-attachment Steps

(2013) Zhiqiang Ku et al.   PLoS One

Study of the Integrated Immune Response Induced by an Inactivated EV71 Vaccine

(2013) Longding Liu et al.   PLoS One

Virus-like particles for enterovirus 71 produced from Saccharomyces cerevisiae potently elicits protective immune responses in mice

(2013) Hao-Yang Li et al.   VACCINE

A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71

(2012) Xiangxi Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Enterovirus type 71 neutralizing antibodies in the serum of macaque monkeys immunized with EV71 virus-like particles

(2012) Yu-Li Lin et al.   VACCINE

Virus-like particles as a highly efficient vaccine platform: Diversity of targets and production systems and advances in clinical development

(2012) Natasha Kushnir et al.   VACCINE

A virus-like particle vaccine for coxsackievirus A16 potently elicits neutralizing antibodies that protect mice against lethal challenge

(2012) Qingwei Liu et al.   VACCINE

Production of EV71 vaccine candidates

(2012) Pele Chong et al.   Human Vaccines & Immunotherapeutics

Antigenicity, animal protective effect and genetic characteristics of candidate vaccine strains of enterovirus 71

(2011) Qunying Mao et al.   ARCHIVES OF VIROLOGY

Aluminum Adjuvant Dose Guidelines in Vaccine Formulation for Preclinical Evaluations

(2011) Simone Vecchi et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Enterovirus 71-related encephalomyelitis: usual and unusual magnetic resonance imaging findings

(2011) Seonah Jang et al.   NEURORADIOLOGY

Purification and Characterization of Enterovirus 71 Viral Particles Produced from Vero Cells Grown in a Serum-Free Microcarrier Bioreactor System

(2011) Chia-Chyi Liu et al.   PLoS One

Formalin-inactivated vaccine provokes cross-protective immunity in a mouse model of human enterovirus 71 infection

(2011) Emily Jane Bek et al.   VACCINE

Establishing China's national standards of antigen content and neutralizing antibody responses for evaluation of enterovirus 71 (EV71) vaccines

(2011) Zhenglun Liang et al.   VACCINE

Immunoprotection elicited by an enterovirus type 71 experimental inactivated vaccine in mice and rhesus monkeys

(2011) Chenghong Dong et al.   VACCINE

Neural pathogenesis of enterovirus 71 infection

(2010) Kuo-Feng Weng et al.   MICROBES AND INFECTION

Enterovirus 71 virus-like particle vaccine: Improved production conditions for enhanced yield

(2010) Cheng-Yu Chung et al.   VACCINE

Generation of neutralizing monoclonal antibodies against Enterovirus 71 using synthetic peptides

(2009) Xiuling Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Immunization with virus-like particles of enterovirus 71 elicits potent immune responses and protects mice against lethal challenge

(2008) Yao-Chi Chung et al.   VACCINE