Obsessive-Compulsive Disorder: Autoimmunity and Neuroinflammation

Treatment of Pediatric Acute-Onset Neuropsychiatric Disorder in a Large Survey Population

(2018) Denise Calaprice et al.   JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY

Treatment of PANDAS and PANS: a systematic review

(2018) Sofia Sigra et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Toxoplasma-infected subjects report an Obsessive-Compulsive Disorder diagnosis more often and score higher in Obsessive-Compulsive Inventory

(2017) J. Flegr et al.   EUROPEAN PSYCHIATRY

Course of Neuropsychiatric Symptoms After Introduction and Removal of Nonsteroidal Anti-Inflammatory Drugs: A Pediatric Observational Study

(2017) Ellen J. Spartz et al.   JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY

Effect of Early and Prophylactic Nonsteroidal Anti-Inflammatory Drugs on Flare Duration in Pediatric Acute-Onset Neuropsychiatric Syndrome: An Observational Study of Patients Followed by an Academic Community-Based Pediatric Acute-Onset Neuropsychiatric Syndrome Clinic

(2017) Kayla D. Brown et al.   JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY

A Double-Blind Randomized Placebo-Controlled Pilot Study of Azithromycin in Youth with Acute-Onset Obsessive–Compulsive Disorder

(2017) Tanya K. Murphy et al.   JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY

Inflammatory dysregulation of monocytes in pediatric patients with obsessive-compulsive disorder

(2017) Natalia Rodríguez et al.   Journal of Neuroinflammation

A total-population multigenerational family clustering study of autoimmune diseases in obsessive–compulsive disorder and Tourette’s/chronic tic disorders

(2017) D Mataix-Cols et al.   MOLECULAR PSYCHIATRY

The relationship between Toxoplasma gondii IgG antibodies and generalized anxiety disorder and obsessive-compulsive disorder in children and adolescents: a new approach

(2017) İsmail Akaltun et al.   NORDIC JOURNAL OF PSYCHIATRY

Inflammation in the Neurocircuitry of Obsessive-Compulsive Disorder

(2017) Sophia Attwells et al.   JAMA Psychiatry

Metabolic and Cardiovascular Complications in Obsessive-Compulsive Disorder: A Total Population, Sibling Comparison Study With Long-Term Follow-up

(2017) Kayoko Isomura et al.   BIOLOGICAL PSYCHIATRY

Pediatric Autoimmune Neuropsychiatry Disorder Associated with Group a Streptococcal Infection: The Role of Surgical Treatment

(2017) P. Pavone et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Serum Cytokine Profiles of Children with Obsessive-Compulsive Disorder Shows the Evidence of Autoimmunity

(2016) Şeref Şimşek et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

N-acetylcysteine augmentation therapy for moderate-to-severe obsessive-compulsive disorder: randomized, double-blind, placebo-controlled trial

(2016) K. Paydary et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Randomized, Controlled Trial of Intravenous Immunoglobulin for Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections

(2016) Kyle A. Williams et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Minocycline combination therapy with fluvoxamine in moderate-to-severe obsessive-compulsive disorder: A placebo-controlled, double-blind, randomized trial

(2016) Sophia Esalatmanesh et al.   PSYCHIATRY AND CLINICAL NEUROSCIENCES

Microglial Dysregulation in OCD, Tourette Syndrome, and PANDAS

(2016) Luciana Frick et al.   Journal of Immunology Research

Autoimmunity against dopamine receptors in neuropsychiatric and movement disorders: a review of Sydenham chorea and beyond

(2015) M. W. Cunningham et al.   Acta Physiologica

Seroprevalence and associated risk factors of Toxoplasma gondii infection in psychiatric patients: a case-control study in eastern China

(2015) W. CONG et al.   EPIDEMIOLOGY AND INFECTION

Cefdinir for Recent-Onset Pediatric Neuropsychiatric Disorders: A Pilot Randomized Trial

(2015) Tanya K. Murphy et al.   JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY

Use of Intravenous Immunoglobulin in the Treatment of Twelve Youths with Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections

(2015) Miro Kovacevic et al.   JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY

Five Youth with Pediatric Acute-Onset Neuropsychiatric Syndrome of Differing Etiologies

(2015) Jennifer Frankovich et al.   JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY

Antineuronal Antibodies in a Heterogeneous Group of Youth and Young Adults with Tics and Obsessive-Compulsive Disorder

(2015) Carol J. Cox et al.   JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY

Therapeutic Plasma Apheresis as a Treatment for 35 Severely Ill Children and Adolescents with Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections

(2015) M. Elizabeth Latimer et al.   JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY

Plasma cytokine abnormalities in drug-naïve, comorbidity-free obsessive–compulsive disorder

(2015) Naren P. Rao et al.   PSYCHIATRY RESEARCH

The Role of Tonsillectomy in the Treatment of Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections (PANDAS)

(2015) Daniel Demesh et al.   JAMA Otolaryngology-Head & Neck Surgery

Neuronal Antibody Biomarkers for Sydenham’s Chorea Identify a New Group of Children with Chronic Recurrent Episodic Acute Exacerbations of Tic and Obsessive Compulsive Symptoms Following a Streptococcal Infection

(2015) Harvey S. Singer et al.   PLoS One

Anti-basal ganglia antibodies in primary obsessive–compulsive disorder: systematic review and meta-analysis

(2014) Daniel M. Pearlman et al.   BRITISH JOURNAL OF PSYCHIATRY

Amantadine Augmentation Therapy for Obsessive Compulsive Patients Resistant to SSRIs—An Open-Label Study

(2014) Rafael Stryjer et al.   CLINICAL NEUROPHARMACOLOGY

Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior

(2014) Yang Zhan et al.   NATURE NEUROSCIENCE

Microglial Dysregulation in Psychiatric Disease

(2013) Luciana Romina Frick et al.   Clinical & Developmental Immunology

Brain Human Monoclonal Autoantibody from Sydenham Chorea Targets Dopaminergic Neurons in Transgenic Mice and Signals Dopamine D2 Receptor: Implications in Human Disease

(2013) C. J. Cox et al.   JOURNAL OF IMMUNOLOGY

Layer V cortical neurons require microglial support for survival during postnatal development

(2013) Masaki Ueno et al.   NATURE NEUROSCIENCE

Dopamine Receptor Autoantibodies Correlate with Symptoms in Sydenham's Chorea

(2013) Hilla Ben-Pazi et al.   PLoS One

Immunity, Inflammation, and Bipolar Disorder: Diagnostic and Therapeutic Implications

(2013) Nora Hamdani et al.   Current Psychiatry Reports

Association study between functional polymorphisms in the TNF-alpha gene and obsessive-compulsive disorder

(2012) Carolina Cappi et al.   ARQUIVOS DE NEURO-PSIQUIATRIA

A cytokine study of adult patients with obsessive-compulsive disorder

(2012) Leonardo F Fontenelle et al.   COMPREHENSIVE PSYCHIATRY

Streptococcus and rheumatic fever

(2012) Madeleine W. Cunningham   CURRENT OPINION IN RHEUMATOLOGY

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

(2012) Dorothy P. Schafer et al.   NEURON

Behavioral, Pharmacological and Immunological Abnormalities after Streptococcal Exposure: A Novel Rat Model of Sydenham Chorea and Related Neuropsychiatric Disorders

(2012) Lior Brimberg et al.   NEUROPSYCHOPHARMACOLOGY

Systematic Review of Proinflammatory Cytokines in Obsessive-Compulsive Disorder

(2012) Simon M. Gray et al.   Current Psychiatry Reports

Clinical Factors Associated with Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections

(2011) Tanya K. Murphy et al.   JOURNAL OF PEDIATRICS

Streptococcal Upper Respiratory Tract Infections and Exacerbations of Tic and Obsessive-Compulsive Symptoms: A Prospective Longitudinal Study

(2011) James F. Leckman et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Obsessive–compulsive disorder in the community: 12-month prevalence, comorbidity and impairment

(2011) Yuki Adam et al.   SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY

Minocycline Augmentation of Pharmacotherapy in Obsessive-Compulsive Disorder

(2010) Carolyn I. Rodriguez et al.   JOURNAL OF CLINICAL PSYCHIATRY

Maternal history of autoimmune disease in children presenting with tics and/or obsessive–compulsive disorder

(2010) T.K. Murphy et al.   JOURNAL OF NEUROIMMUNOLOGY

Is there any role of Toxoplasma gondii in the etiology of obsessive–compulsive disorder?

(2010) Ozlem Miman et al.   PSYCHIATRY RESEARCH

Streptococcal Upper Respiratory Tract Infections and Psychosocial Stress Predict Future Tic and Obsessive-Compulsive Symptom Severity in Children and Adolescents with Tourette Syndrome and Obsessive-Compulsive Disorder

(2009) Haiqun Lin et al.   BIOLOGICAL PSYCHIATRY

Anti-brain antibodies in adult patients with obsessive–compulsive disorder

(2009) Giuseppe Maina et al.   JOURNAL OF AFFECTIVE DISORDERS

Obsessive–compulsive symptom dimensions in the general population: Results from an epidemiological study in six European countries

(2009) M.A. Fullana et al.   JOURNAL OF AFFECTIVE DISORDERS

Antineuronal antibodies in OCD: Comparisons in children with OCD-only, OCD+chronic tics and OCD+PANDAS

(2009) Colin Gause et al.   JOURNAL OF NEUROIMMUNOLOGY

Streptococcal infection, Tourette syndrome, and OCD: Is there a connection?

(2009) A. Schrag et al.   NEUROLOGY

Anti-Brain Autoantibodies and Altered Excitatory Neurotransmitters in Obsessive–Compulsive Disorder

(2009) Sagnik Bhattacharyya et al.   NEUROPSYCHOPHARMACOLOGY

Anxiety disorders and comorbid medical illness

(2008) Peter P. Roy-Byrne et al.   GENERAL HOSPITAL PSYCHIATRY

Neuropsychiatric Disorders Associated With Streptococcal Infection: A Case-Control Study Among Privately Insured Children

(2008) Douglas L. Leslie et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Streptococcal Infection and Exacerbations of Childhood Tics and Obsessive-Compulsive Symptoms: A Prospective Blinded Cohort Study

(2008) R. Kurlan et al.   PEDIATRICS

Mycoplasma pneumoniae Infection and Obsessive-Compulsive Disease: A Case Report

(2007) Tugba Erener Ercan et al.   JOURNAL OF CHILD NEUROLOGY

Antineuronal antibodies in a group of children with obsessive–compulsive disorder and Tourette syndrome

(2006) Astrid Morer et al.   JOURNAL OF PSYCHIATRIC RESEARCH