Journal
JOURNAL OF FUNCTIONAL FOODS
Volume 60, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.jff.2019.103416
Keywords
Zebrafish; Microbiota; Saturated fatty acids; Omega-3 Fish oil
Categories
Funding
- Maromega project
- Basque Country Government (Department of the Environment, Regional Planning, Agriculture and Fisheries)
- Basque Country Government
- Ramon y Cajal program [RYC-2013-13666]
- Spanish Ministry of Economy and Competitiveness [AGL2017-86757-R]
Ask authors/readers for more resources
Diet is one of the main factors affecting host's health. The aim of this work was to study the interaction among nutrition, microbiota and host, using zebrafish adults as animal model. Thus, the effects of a high-saturated-fat diet, and its supplementation with a commercial fish-oil on fish lipid profile, intestinal microbiota and blood glucose were evaluated. The dietary saturated fat changed the fish lipid profile, microbial community composition, and its metabolism. Saturated fatty acids levels were higher in fish fed the high-saturated-fat diet, which correlated with an increased in Pseudomonas. Otherwise, the commercial fish-oil intake ameliorated the effect of the fat on the lipid profile, lowering saturated fatty acid levels while increasing polyunsaturated fatty acids. It also contributed to limit the growth of Pseudomonas on intestinal microbial community. Furthermore, blood glucose diminished in animals fed fish-oil supplemented diet. This suggests that fish-oil may mitigate the effect of the high-saturated fat-diet.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available