Axonal Computations

Soma-axon coupling configurations that enhance neuronal coincidence detection

(2019) Joshua H. Goldwyn et al.   PLoS Computational Biology

Beyond plasticity: the dynamic impact of electrical synapses on neural circuits

(2019) Pepe Alcamí et al.   NATURE REVIEWS NEUROSCIENCE

Robustness to axon initial segment variation is explained by somatodendritic excitability in rat substantia nigra dopaminergic neurons

(2019) Estelle Moubarak et al.   JOURNAL OF NEUROSCIENCE

Past and Future of Analog-Digital Modulation of Synaptic Transmission

(2019) Mickael Zbili et al.   Frontiers in Cellular Neuroscience

Electrical Synapses Enhance and Accelerate Interneuron Recruitment in Response to Coincident and Sequential Excitation

(2018) Pepe Alcami   Frontiers in Cellular Neuroscience

Ephaptic Coupling Promotes Synchronous Firing of Cerebellar Purkinje Cells

(2018) Kyung-Seok Han et al.   NEURON

An axon initial segment is required for temporal precision in action potential encoding by neuronal populations

(2018) Elinor Lazarov et al.   Science Advances

Plasticity of intrinsic neuronal excitability

(2018) Dominique Debanne et al.   CURRENT OPINION IN NEUROBIOLOGY

Sound-Evoked Activity Influences Myelination of Brainstem Axons in the Trapezoid Body

(2017) James L. Sinclair et al.   JOURNAL OF NEUROSCIENCE

Sodium Channel β2 Subunits Prevent Action Potential Propagation Failures at Axonal Branch Points

(2017) In Ha Cho et al.   JOURNAL OF NEUROSCIENCE

Axo-myelinic neurotransmission: a novel mode of cell signalling in the central nervous system

(2017) I. Micu et al.   NATURE REVIEWS NEUROSCIENCE

Superresolution imaging reveals activity-dependent plasticity of axon morphology linked to changes in action potential conduction velocity

(2017) Ronan Chéreau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Label-free optical detection of action potential in mammalian neurons

(2017) Subrata Batabyal et al.   Biomedical Optics Express

Efficient encoding of motion is mediated by gap junctions in the fly visual system

(2017) Siwei Wang et al.   PLoS Computational Biology

Node of Ranvier length as a potential regulator of myelinated axon conduction speed

(2017) I Lorena Arancibia-Cárcamo et al.   eLife

From Neuron Biophysics to Orientation Selectivity in Electrically Coupled Networks of Neocortical L2/3 Large Basket Cells

(2016) Oren Amsalem et al.   CEREBRAL CORTEX

KV1 channels identified in rodent myelinated axons, linked to Cx29 in innermost myelin: support for electrically active myelin in mammalian saltatory conduction

(2016) John E. Rash et al.   JOURNAL OF NEUROPHYSIOLOGY

Low Somatic Sodium Conductance Enhances Action Potential Precision in Time-Coding Auditory Neurons

(2016) Yang Yang et al.   JOURNAL OF NEUROSCIENCE

Dynamic Modulation of Myelination in Response to Visual Stimuli Alters Optic Nerve Conduction Velocity

(2016) A. Etxeberria et al.   JOURNAL OF NEUROSCIENCE

Rapid production of new oligodendrocytes is required in the earliest stages of motor-skill learning

(2016) Lin Xiao et al.   NATURE NEUROSCIENCE

Synapse-Level Determination of Action Potential Duration by K + Channel Clustering in Axons

(2016) Matthew J.M. Rowan et al.   NEURON

Ultrastructural anatomy of nodes of Ranvier in the peripheral nervous system as revealed by STED microscopy

(2016) Elisa D’Este et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chandelier Cells in Functional and Dysfunctional Neural Circuits

(2016) Yiqing Wang et al.   Frontiers in Neural Circuits

The Circuitry of Olfactory Projection Neurons in the Brain of the Honeybee, Apis mellifera

(2016) Hanna Zwaka et al.   Frontiers in Neuroanatomy

Decreased temporal precision of neuronal signaling as a candidate mechanism of auditory processing disorder

(2015) Conny Kopp-Scheinpflug et al.   HEARING RESEARCH

The evolution of vertebrate and invertebrate myelin: a theoretical computational study

(2015) Ann M. Castelfranco et al.   JOURNAL OF COMPUTATIONAL NEUROSCIENCE

Impact of single-site axonal GABAergic synaptic events on cerebellar interneuron activity

(2015) Javier Zorrilla de San Martin et al.   JOURNAL OF GENERAL PHYSIOLOGY

Neuronal activity biases axon selection for myelination in vivo

(2015) Jacob H Hines et al.   NATURE NEUROSCIENCE

A new mechanism of nervous system plasticity: activity-dependent myelination

(2015) R. Douglas Fields   NATURE REVIEWS NEUROSCIENCE

Control of Inhibitory Synaptic Outputs by Low Excitability of Axon Terminals Revealed by Direct Recording

(2015) Shin-ya Kawaguchi et al.   NEURON

Mechanically Activated Ion Channels

(2015) Sanjeev S. Ranade et al.   NEURON

Tuning of Ranvier node and internode properties in myelinated axons to adjust action potential timing

(2015) Marc C. Ford et al.   Nature Communications

Presynaptic hyperpolarization induces a fast analogue modulation of spike-evoked transmission mediated by axonal sodium channels

(2015) Sylvain Rama et al.   Nature Communications

Mechanical surface waves accompany action potential propagation

(2015) Ahmed El Hady et al.   Nature Communications

Calcium-Activated Potassium Channels at Nodes of Ranvier Secure Axonal Spike Propagation

(2015) Jan Gründemann et al.   Cell Reports

Modelling the Effects of Electrical Coupling between Unmyelinated Axons of Brainstem Neurons Controlling Rhythmic Activity

(2015) Michael J. Hull et al.   PLoS Computational Biology

Analog modulation of spike-evoked transmission in CA3 circuits is determined by axonal Kv1.1 channels in a time-dependent manner

(2014) Andrzej Bialowas et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Action Potential Generation in an Anatomically Constrained Model of Medial Superior Olive Axons

(2014) S. Lehnert et al.   JOURNAL OF NEUROSCIENCE

Activity-Dependent and Activity-Independent Development of the Axon Initial Segment

(2014) H. Kuba et al.   JOURNAL OF NEUROSCIENCE

Dendrites Impact the Encoding Capabilities of the Axon

(2014) G. Eyal et al.   JOURNAL OF NEUROSCIENCE

Ultra-rapid axon-axon ephaptic inhibition of cerebellar Purkinje cells by the pinceau

(2014) Antonin Blot et al.   NATURE NEUROSCIENCE

A supercritical density of Na+ channels ensures fast signaling in GABAergic interneuron axons

(2014) Hua Hu et al.   NATURE NEUROSCIENCE

Motor skill learning requires active central myelination

(2014) I. A. McKenzie et al.   SCIENCE

Human Slack Potassium Channel Mutations Increase Positive Cooperativity between Individual Channels

(2014) Grace E. Kim et al.   Cell Reports

Axonal Noise as a Source of Synaptic Variability

(2014) Ali Neishabouri et al.   PLoS Computational Biology

Computationally efficient simulation of electrical activity at cell membranes interacting with self-generated and externally imposed electric fields

(2013) Andres Agudelo-Toro et al.   Journal of Neural Engineering

Dysmyelination of Auditory Afferent Axons Increases the Jitter of Action Potential Timing during High-Frequency Firing

(2013) J. H. Kim et al.   JOURNAL OF NEUROSCIENCE

Motor Skill Learning Induces Changes in White Matter Microstructure and Myelination

(2013) C. Sampaio-Baptista et al.   JOURNAL OF NEUROSCIENCE

Oligodendrocyte Dynamics in the Healthy Adult CNS: Evidence for Myelin Remodeling

(2013) Kaylene M. Young et al.   NEURON

Estimating functional connectivity in an electrically coupled interneuron network

(2013) P. Alcami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sharpness of Spike Initiation in Neurons Explained by Compartmentalization

(2013) Romain Brette   PLoS Computational Biology

Label-Free Imaging of Membrane Potential Using Membrane Electromotility

(2012) Seungeun Oh et al.   BIOPHYSICAL JOURNAL

Increasing Internodal Distance in Myelinated Nerves Accelerates Nerve Conduction to a Flat Maximum

(2012) Lai Man N. Wu et al.   CURRENT BIOLOGY

In vivo dual intra- and extracellular recordings suggest bidirectional coupling between CA1 pyramidal neurons

(2012) Edith Chorev et al.   JOURNAL OF NEUROPHYSIOLOGY

The Energetics of CNS White Matter

(2012) J. J. Harris et al.   JOURNAL OF NEUROSCIENCE

The mechanobiology of brain function

(2012) William J. Tyler   NATURE REVIEWS NEUROSCIENCE

A Small Fraction of Strongly Cooperative Sodium Channels Boosts Neuronal Encoding of High Frequencies

(2012) Min Huang et al.   PLoS One

Mechanistic basis for low threshold mechanosensitivity in voltage-dependent K+ channels

(2012) D. Schmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Segregation of Axonal and Somatic Activity During Fast Network Oscillations

(2012) T. Dugladze et al.   SCIENCE

Characterization of the axon initial segment (AIS) of motor neurons and identification of a para-AIS and a juxtapara-AIS, organized by protein 4.1B

(2011) Amandine Duflocq et al.   BMC BIOLOGY

Predicting myelinated axon activation using spatial characteristics of the extracellular field

(2011) E J Peterson et al.   Journal of Neural Engineering

Ultrafast Population Encoding by Cortical Neurons

(2011) T. Tchumatchenko et al.   JOURNAL OF NEUROSCIENCE

Sparse But Highly Efficient Kv3 Outpace BKCa Channels in Action Potential Repolarization at Hippocampal Mossy Fiber Boutons

(2011) H. Alle et al.   JOURNAL OF NEUROSCIENCE

Multiple models to capture the variability in biological neurons and networks

(2011) Eve Marder et al.   NATURE NEUROSCIENCE

First Node of Ranvier Facilitates High-Frequency Burst Encoding

(2011) Maarten H.P. Kole   NEURON

Spike Onset Dynamics and Response Speed in Neuronal Populations

(2011) Wei Wei et al.   PHYSICAL REVIEW LETTERS

Ankyrin G restricts ion channel diffusion at the axonal initial segment before the establishment of the diffusion barrier

(2010) Anna Brachet et al.   JOURNAL OF CELL BIOLOGY

Mechanisms for Adjusting Interaural Time Differences to Achieve Binaural Coincidence Detection

(2010) A. H. Seidl et al.   JOURNAL OF NEUROSCIENCE

Action Potentials Initiate in the Axon Initial Segment and Propagate through Axon Collaterals Reliably in Cerebellar Purkinje Neurons

(2010) A. Foust et al.   JOURNAL OF NEUROSCIENCE

Kinetic Properties and Functional Dynamics of Sodium Channels during Repetitive Spiking in a Slow Pacemaker Neuron

(2010) L. S. Milescu et al.   JOURNAL OF NEUROSCIENCE

RAPID REPORT: Initiation of simple and complex spikes in cerebellar Purkinje cells

(2010) Lucy M. Palmer et al.   JOURNAL OF PHYSIOLOGY-LONDON

Morphological and electrical properties of oligodendrocytes in the white matter of the corpus callosum and cerebellum

(2010) Yamina Bakiri et al.   JOURNAL OF PHYSIOLOGY-LONDON

Activity-dependent relocation of the axon initial segment fine-tunes neuronal excitability

(2010) Matthew S. Grubb et al.   NATURE

Na+ imaging reveals little difference in action potential–evoked Na+ influx between axon and soma

(2010) Ilya A Fleidervish et al.   NATURE NEUROSCIENCE

Slow integration leads to persistent action potential firing in distal axons of coupled interneurons

(2010) Mark E J Sheffield et al.   NATURE NEUROSCIENCE

Neuronal arithmetic

(2010) R. Angus Silver   NATURE REVIEWS NEUROSCIENCE

The axon initial segment and the maintenance of neuronal polarity

(2010) Matthew N. Rasband   NATURE REVIEWS NEUROSCIENCE

Presynaptic Miniature Gabaergic Currents in Developing Interneurons

(2010) Federico F. Trigo et al.   NEURON

Correlations and Synchrony in Threshold Neuron Models

(2010) Tatjana Tchumatchenko et al.   PHYSICAL REVIEW LETTERS

Molecular Identity of Dendritic Voltage-Gated Sodium Channels

(2010) A. Lorincz et al.   SCIENCE

Impact of Spikelets on Hippocampal CA1 Pyramidal Cell Activity During Spatial Exploration

(2010) J. Epsztein et al.   SCIENCE

A Selective Filter for Cytoplasmic Transport at the Axon Initial Segment

(2009) Ai-hong Song et al.   CELL

Conditional Bursting Enhances Resonant Firing in Neocortical Layer 2-3 Pyramidal Neurons

(2009) M. H. Higgs et al.   JOURNAL OF NEUROSCIENCE

How the Optic Nerve Allocates Space, Energy Capacity, and Information

(2009) J. A. Perge et al.   JOURNAL OF NEUROSCIENCE

Distinct contributions of Nav1.6 and Nav1.2 in action potential initiation and backpropagation

(2009) Wenqin Hu et al.   NATURE NEUROSCIENCE

A nonsynaptic mechanism underlying interictal discharges in human epileptic neocortex

(2009) A. K. Roopun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct nonuniform cable properties optimize rapid and efficient activation of fast-spiking GABAergic interneurons

(2009) A. Norenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cortical Action Potential Backpropagation Explains Spike Threshold Variability and Rapid-Onset Kinetics

(2008) Y. Yu et al.   JOURNAL OF NEUROSCIENCE

Autonomous initiation and propagation of action potentials in neurons of the subthalamic nucleus

(2008) Jeremy F. Atherton et al.   JOURNAL OF PHYSIOLOGY-LONDON

Action potential initiation and propagation in hippocampal mossy fibre axons

(2008) Christoph Schmidt-Hieber et al.   JOURNAL OF PHYSIOLOGY-LONDON

Action potential generation requires a high sodium channel density in the axon initial segment

(2008) Maarten H P Kole et al.   NATURE NEUROSCIENCE

Understanding Synapses: Past, Present, and Future

(2008) Thomas C. Südhof et al.   NEURON

Heterogeneous Ca2+ influx along the adult calyx of held: A structural and computational study

(2008) G.A. Spirou et al.   NEUROSCIENCE

Voltage-dependent K+ channel gating and voltage sensor toxin sensitivity depend on the mechanical state of the lipid membrane

(2008) D. Schmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA