Structural Insights on Retroviral DNA Integration: Learning from Foamy Viruses
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Structural Insights on Retroviral DNA Integration: Learning from Foamy Viruses
Authors
Keywords
-
Journal
Viruses-Basel
Volume 11, Issue 9, Pages 770
Publisher
MDPI AG
Online
2019-08-23
DOI
10.3390/v11090770
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Structure Based Drug Design: Clinically relevant HIV1 Integrase Inhibitors
- (2019) Maninder Kaur et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Nucleosome DNA unwrapping does not affect prototype foamy virus integration efficiency or site selection
- (2019) Randi M. Mackler et al. PLoS One
- Human H4 tail stimulates HIV-1 integration through binding to the carboxy-terminal domain of integrase
- (2019) Eric Mauro et al. NUCLEIC ACIDS RESEARCH
- Prototype foamy virus integrase is promiscuous for target choice
- (2018) R.M. Mackler et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- NP220 mediates silencing of unintegrated retroviral DNA
- (2018) Yiping Zhu et al. NATURE
- An effective HIV-1 integrase inhibitor screening platform: Rationality validation of drug screening, conformational mobility and molecular recognition analysis for PFV integrase complex with viral DNA
- (2017) Wenyi Du et al. JOURNAL OF MOLECULAR GRAPHICS & MODELLING
- Modulation of the functional association between the HIV-1 intasome and the nucleosome by histone amino-terminal tails
- (2017) Mohamed S. Benleulmi et al. Retrovirology
- Cryo-EM structures and atomic model of the HIV-1 strand transfer complex intasome
- (2017) Dario Oliveira Passos et al. SCIENCE
- A supramolecular assembly mediates lentiviral DNA integration
- (2017) Allison Ballandras-Colas et al. SCIENCE
- Antiviral Activity of Bictegravir (GS-9883), a Novel Potent HIV-1 Integrase Strand Transfer Inhibitor with an Improved Resistance Profile
- (2016) Manuel Tsiang et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Histones Are Rapidly Loaded onto Unintegrated Retroviral DNAs Soon after Nuclear Entry
- (2016) Gary Z. Wang et al. Cell Host & Microbe
- Retroviral DNA Integration
- (2016) Paul Lesbats et al. CHEMICAL REVIEWS
- Crystal structure of the Rous sarcoma virus intasome
- (2016) Zhiqi Yin et al. NATURE
- Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function
- (2016) Allison Ballandras-Colas et al. NATURE
- Retroviral intasomes search for a target DNA by 1D diffusion which rarely results in integration
- (2016) Nathan D. Jones et al. Nature Communications
- Comparison of Newly Assembled Full Length HIV-1 Integrase With Prototype Foamy Virus Integrase: Structure-Function Prospective
- (2016) Mohammad Reza Dayer Jundishapur Journal of Microbiology
- Design and synthesis of N-methylpyrimidone derivatives as HIV-1 integrase inhibitors
- (2015) Yujie Wang et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Structure–Activity Relationship of Pyrrolyl Diketo Acid Derivatives as Dual Inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H Domain
- (2015) Giuliana Cuzzucoli Crucitti et al. JOURNAL OF MEDICINAL CHEMISTRY
- Structural basis for retroviral integration into nucleosomes
- (2015) Daniel P. Maskell et al. NATURE
- DNA Physical Properties and Nucleosome Positions Are Major Determinants of HIV-1 Integrase Selectivity
- (2015) Monica Naughtin et al. PLoS One
- Structural Studies of the HIV-1 Integrase Protein: Compound Screening and Characterization of a DNA-Binding Inhibitor
- (2015) Peter K. Quashie et al. PLoS One
- Outer domains of integrase within retroviral intasomes are dispensible for catalysis of DNA integration
- (2015) Min Li et al. PROTEIN SCIENCE
- Key determinants of target DNA recognition by retroviral intasomes
- (2015) Erik Serrao et al. Retrovirology
- Intasome architecture and chromatin density modulate retroviral integration into nucleosome
- (2015) Mohamed Benleulmi et al. Retrovirology
- Formulation and pharmacology of long-acting cabotegravir
- (2015) Christine Trezza et al. Current Opinion in HIV and AIDS
- Antiviral Characteristics of GSK1265744, an HIV Integrase Inhibitor Dosed Orally or by Long-Acting Injection
- (2014) Tomokazu Yoshinaga et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Structural Basis of hAT Transposon End Recognition by Hermes, an Octameric DNA Transposase from Musca domestica
- (2014) Alison B. Hickman et al. CELL
- Combined ligand and structure-based approaches on HIV-1 integrase strand transfer inhibitors
- (2014) Karnati Konda Reddy et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Integrase residues that determine nucleotide preferences at sites of HIV-1 integration: implications for the mechanism of target DNA binding
- (2014) Erik Serrao et al. NUCLEIC ACIDS RESEARCH
- Engineered Hyperactive Integrase for Concerted HIV-1 DNA Integration
- (2014) Min Li et al. PLoS One
- Carbamoyl Pyridone HIV-1 Integrase Inhibitors 3. A Diastereomeric Approach to Chiral Nonracemic Tricyclic Ring Systems and the Discovery of Dolutegravir (S/GSK1349572) and (S/GSK1265744)
- (2013) Brian A. Johns et al. JOURNAL OF MEDICINAL CHEMISTRY
- A Homology Model of HIV-1 Integrase and Analysis of Mutations Designed to Test the Model
- (2013) Barry C. Johnson et al. JOURNAL OF MOLECULAR BIOLOGY
- Substrate Recognition and Motion Mode Analyses of PFV Integrase in Complex with Viral DNA via Coarse-Grained Models
- (2013) Jianping Hu et al. PLoS One
- 3′-Processing and strand transfer catalysed by retroviral integrasein crystallo
- (2012) Stephen Hare et al. EMBO JOURNAL
- Study on the interactions between diketo-acid inhibitors and prototype foamy virus integrase-DNA complex via molecular docking and comparative molecular dynamics simulation methods
- (2012) Jian-Ping Hu et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- The Mu transpososome structure sheds light on DDE recombinase evolution
- (2012) Sherwin P. Montaño et al. NATURE
- The emerging diversity of transpososome architectures
- (2012) Fred Dyda et al. QUARTERLY REVIEWS OF BIOPHYSICS
- Solution Conformations of Prototype Foamy Virus Integrase and Its Stable Synaptic Complex with U5 Viral DNA
- (2012) Kushol Gupta et al. STRUCTURE
- Molecular Dynamics Approaches Estimate the Binding Energy of HIV-1 Integrase Inhibitors and Correlate withIn VitroActivity
- (2011) Barry C. Johnson et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Resistance to raltegravir highlights integrase mutations at codon 148 in conferring cross-resistance to a second-generation HIV-1 integrase inhibitor
- (2011) Olivia Goethals et al. ANTIVIRAL RESEARCH
- Structural and Functional Analyses of the Second-Generation Integrase Strand Transfer Inhibitor Dolutegravir (S/GSK1349572)
- (2011) S. Hare et al. MOLECULAR PHARMACOLOGY
- Authentic HIV-1 integrase inhibitors
- (2010) Chenzhong Liao et al. Future Medicinal Chemistry
- Solution Conformation and Dynamics of the HIV-1 Integrase Core Domain
- (2010) Nicholas C. Fitzkee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Characterization of Biochemical Properties of Feline Foamy Virus Integrase
- (2010) Cha-Gyun Shin JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
- Retroviral intasome assembly and inhibition of DNA strand transfer
- (2010) Stephen Hare et al. NATURE
- The mechanism of retroviral integration from X-ray structures of its key intermediates
- (2010) Goedele N. Maertens et al. NATURE
- DNA transposon Hermes inserts into DNA in nucleosome-free regions in vivo
- (2010) S. Gangadharan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure-based modeling of the functional HIV-1 intasome and its inhibition
- (2010) L. Krishnan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular mechanisms of retroviral integrase inhibition and the evolution of viral resistance
- (2010) S. Hare et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Retroviral integrase superfamily: the structural perspective
- (2009) Marcin Nowotny EMBO REPORTS
- Raltegravir: The first HIV integrase inhibitor
- (2008) Jennifer Cocohoba et al. CLINICAL THERAPEUTICS
- Functional and structural characterization of the integrase from the prototype foamy virus
- (2008) Eugene Valkov et al. NUCLEIC ACIDS RESEARCH
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started