Article
Infectious Diseases
Miao Zhang, Jing Liu, Yu-Chen Pan, Hui-Li Liu, Jing Shu, Xiao-Ming Wu, Yang Yang
Summary: The aim of this study was to analyze the prevalence of vaginal flora and drug resistance in bacterial vaginitis among girls. A total of 3099 girls with vaginitis were included in the study, and the results showed that 399 girls had a positive bacterial culture of vaginal secretions. The top three infective bacteria were Haemophilus influenzae, Staphylococcus aureus, and Streptococcus agalactiae.
INFECTION AND DRUG RESISTANCE
(2023)
Article
Immunology
Zheng Jin, Yaping Wei, Shanshan Hu, Minhui Sun, Mengdie Fang, Hongzhang Shen, Jianfeng Yang, Xiaofeng Zhang, Hangbin Jin
Summary: Early enteral nutrition in predicted severe acute gallstone pancreatitis patients can reduce in-hospital mortality, length of hospital stay, need for intensive care admission, and hospital care costs, but does not significantly reduce infection-related complications.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Gastroenterology & Hepatology
Ting Zhou, Chao-lian Xie, Yong Chen, Yan Deng, Jia-long Wu, Rui Liang, Guo-dong Yang, Xiao-ming Zhang
Summary: The study developed radiomics models based on MRI to predict early extrapancreatic necrosis in acute pancreatitis. The models showed better predictive performance than clinical models and imaging scores.
Article
Medicine, General & Internal
Yanqing Wen, Hong Chen, Xin Ming, Xiaoyan Chen, Wei Zhou
Summary: This study aimed to assess the risk factors, pathogenic bacteria, and drug sensitivity of maternal sepsis in full-term pregnant women. Cesarean section, temperature, white blood cell count, procalcitonin, C-reactive protein, and neutrophil ratio were found to be associated with sepsis. Escherichia coli was the most common pathogen in positive blood cultures, with high sensitivity to certain antibiotics.
Article
Multidisciplinary Sciences
Tongtian Ni, Yi Wen, Bing Zhao, Ning Ning, Erzhen Chen, Enqiang Mao, Weijun Zhou
Summary: This study retrospectively analyzed the characteristics, influencing factors, and prognosis of extrapancreatic infection in patients with acute pancreatitis. The findings showed that extrapancreatic infection is associated with pancreatic necrosis, the rate of laparotomy, length of hospital stay, and in-hospital mortality. This highlights the need to prevent and monitor extrapancreatic infection in the early stage.
Article
Radiology, Nuclear Medicine & Medical Imaging
Ting Zhou, Meng-yue Tang, Yan Deng, Jia-long Wu, Huan Sun, Yong Chen, Tian-wu Chen, Xiao-ming Zhang
Summary: The study demonstrated significant differences in MRI characteristics, severity index scores, and clinical features between patients with early extrapancreatic necrosis and peripancreatic fluid collections. The area of extrapancreatic collections emerged as a crucial indicator for predicting extrapancreatic necrosis.
ACADEMIC RADIOLOGY
(2021)
Article
Immunology
Qiang Sun, Zixuan Li, Panpan Wang, Junfang Zhao, Shuai Chen, Minglei Sun
Summary: This study investigated the microbial characteristics of maxillofacial infections (MI) and descending necrotizing mediastinitis (DNM) using metagenomic next-generation sequencing. The results showed that DNM group had higher species richness and diversity, with differential species including Bacillus, Lactobacillus, Streptococcaceae, and Streptococcus. Correlation analysis revealed associations between clinical characteristics and relative abundance of specific pathogens.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Spenser R. Simpson, Alexandria E. Kesterson, Justin H. Wilde, Zoraiz Qureshi, Bijoy Kundu, Mark P. Simons, Kiel D. Neumann
Summary: Infectious diseases continue to be the main cause of illness and death globally. The increasing prevalence of multidrug-resistant bacteria is a growing concern, resulting from various selection pressures. Many of these bacterial infections are acquired in hospitals and have been classified as urgent threats by the Centers for Disease Control and Prevention. Therefore, there is an urgent need to improve the clinical management of bacterial infections through new methods of bacterial identification and antibiotic efficacy monitoring in vivo.
JOURNAL OF NUCLEAR MEDICINE
(2023)
Article
Infectious Diseases
Xuemei Li, Zhipeng Du, Ziwei Tang, Qin Wen, Qingfeng Cheng, Yunhua Cui
Summary: This study investigated the distribution and susceptibility of pathogenic bacteria in patients with Diabetic foot ulcer complicated by necrotizing fasciitis (DNF) and provided empirical antibacterial guidance for the clinic.
BMC INFECTIOUS DISEASES
(2022)
Article
Infectious Diseases
Deng Pan, Pin Peng, Yu Fang, Jun Lu, Minghao Fang
Summary: The study investigated the distribution and drug resistance of pathogenic bacteria in sepsis bloodstream infection patients with renal insufficiency. Gram-negative bacteria were found to be the main pathogens, and they exhibited higher resistance rates to multiple antibiotics. The study highlights the difficulties in treating these infections and the need for prolonged antimicrobial drug administration.
INFECTION AND DRUG RESISTANCE
(2022)
Article
Biophysics
Hao Yang, Rodrigo Ledesma-Amaro, Hong Gao, Yao Ren, Ruijie Deng
Summary: Pathogenic biosafety is a global concern, and there is a high demand for precise, rapid, and field-deployable tools for analyzing pathogenic biosafety. Recently developed biotechnological tools, especially those utilizing CRISPR/Cas systems coupled with nanotechnologies, have great potential for point-of-care testing of pathogen infection. This review introduces the working principle of class II CRISPR/Cas systems for detecting biomarkers, summarizes the applications of CRISPR tools in detecting pathogens and profiling their genotypes or phenotypes, and discusses the challenges and opportunities of CRISPR-based biosensors in pathogenic biosafety analysis.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Agriculture, Dairy & Animal Science
Maria Foti, Rosario Grasso, Vittorio Fisichella, Antonietta Mascetti, Marco Colnaghi, Maria Grasso, Maria Teresa Spena
Summary: This study aimed to evaluate the levels of drug resistance among 413 Gram-negative and 183 Gram-positive bacteria isolated from six bat populations in Sicilian and Calabrian territory (Italy). The results showed high resistance and the presence of multi-drug-resistant strains.
Review
Microbiology
Dipanjan Dutta, Anupam Kaushik, Dhirendra Kumar, Satyabrata Bag
Summary: Foodborne illness caused by pathogenic Vibrios is often linked to raw or undercooked seafood consumption. Symptoms include watery diarrhea, stomach cramping, nausea, vomiting, fever, and chills. Treatment typically involves oral or intravenous rehydration salts and antibiotics.
FRONTIERS IN MICROBIOLOGY
(2021)
Review
Biotechnology & Applied Microbiology
M. Amirul Islam, Ahasanul Karim, Baranitharan Ethiraj, Topu Raihan, Abudukeremu Kadier
Summary: Traditional biosensors have limitations in terms of specificity and sensitivity for pathogenic bacteria detection. Antimicrobial peptides (AMPs), with high stability and multiple binding sites for capturing bacteria, have shown potential as alternative bio-recognition ligands. The conjugation of chemo-selective groups with AMPs allows effective immobilization on biosensor surfaces.
BIOTECHNOLOGY ADVANCES
(2022)
Article
Economics
Joshua S. Gans
Summary: This paper examines the value of different tests from an information-theoretic approach and stresses the importance of tailoring test scoring based on the decision being made.
MANAGERIAL AND DECISION ECONOMICS
(2022)