Review
Plant Sciences
Pankaj Sharma, Arun Meyyazhagan, Murugesh Easwaran, Mayur Mukut Murlidhar Sharma, Sahil Mehta, Vimal Pandey, Wen-Chao Liu, Hesam Kamyab, Balamuralikrishnan Balasubramanian, Rathinasamy Baskaran, Jiri Jaromir Klemes, Mohsen Mesbah, Shreeshivadasan Chelliapan
Summary: During dormancy, seeds are exposed to various shocks, both biotic and abiotic, which can be improved by seed priming techniques like treatment with exogenous H2S donors. The H2S molecule plays a role in signaling and physiological processes related to seed germination, stress tolerance, and gene expression.
PLANT GROWTH REGULATION
(2022)
Article
Plant Sciences
Zhiqing Wang, Feng He, Yao Mu, Liping Zhang, Zhiqiang Liu, Danmei Liu, Jinbao Yang, Zhuping Jin, Yanxi Pei
Summary: The overexpression of CBL increases the tolerance of plants to osmotic stress and reduces the aperture of stomata, playing an important role in plant resistance to abiotic stress.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2022)
Article
Plant Sciences
Sahana Basu, Gautam Kumar
Summary: Silicon regulates gene expression in plants under stress, reducing the accumulation of reactive oxygen and nitrogen species, activating antioxidant defense systems, maintaining cellular redox homeostasis, and enhancing stress tolerance.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2021)
Review
Plant Sciences
Rachele Ingrisano, Edoardo Tosato, Paolo Trost, Libero Gurrieri, Francesca Sparla
Summary: Proteinogenic amino acids are crucial for protein synthesis in plants and are also involved in regulating stress responses. This review highlights the roles of amino acids as energy sources, osmolyte precursors, and secondary metabolite precursors. The importance of proline and cysteine in drought stress response is also discussed.
Article
Plant Sciences
Mona F. A. Dawood, Abdullah Al Mamun Sohag, Md Tahjib-Ul-Arif, Arafat Abdel Hamed Abdel Latef
Summary: The study found that H2S priming can protect artichoke plants under saline-alkaline and/or aniline stress, mitigate the detrimental effects of stress, and enhance stress tolerance by improving the antioxidant system.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2021)
Article
Horticulture
Zhiqiang Liu, Juanjuan Qu, Liping Zhang, Xin Liu, Guangdong Yang, Yanxi Pei
Summary: The study identified CsaLCD and CsaDES2 as the main enzymes responsible for endogenous H2S production in cucumber, playing a crucial role in H2S generation during stress responses.
SCIENTIA HORTICULTURAE
(2021)
Article
Plant Sciences
Luisa Gouveia Lana, Lara Matos de Araujo, Thamara Ferreira Silva, Luzia Valentina Modolo
Summary: This review focuses on the interplay among gasotransmitters NO, CO, H2S, and potassium ions in plants, particularly in response to high salinity stress. It also discusses findings from studies on plants under water deficit and metal stress, since these abiotic stresses share similarities with salt stress. Molecular targets of gasotransmitters NO, CO, and H2S in root and guard cells that promote plant tolerance to salt stress are highlighted as well.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2021)
Article
Plant Sciences
Mukhtar Ahmed, Shah Fahad, Muhammad Arif Ali, Sajjad Hussain, Muhammad Tariq, Fariha Ilyas, Shakeel Ahmad, Shah Saud, Hafiz Mohkum Hammad, Wajid Nasim, Chao Wu, Hongyan Liu
Summary: Hydrogen sulfide (H2S) plays a crucial role in signaling, metabolism, and stress tolerance in plants as an essential gaseous molecule. Produced from various sources, its interaction with other molecules helps plants resist both biotic and abiotic stress effectively.
JOURNAL OF PLANT GROWTH REGULATION
(2021)
Article
Environmental Sciences
Parna Dutta, Arunima Sengupta, Santanu Chakraborty
Summary: The article explores the harmful effects and signaling pathways of arterial and aortic valve calcification, proposing a new strategy targeting the mechanism of calcification and emphasizing the application of epigenetics in reducing calcification harm. Further clinical trials are needed for a comprehensive understanding and application of this strategy.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Food Science & Technology
Zhimin Mao, Haitao Li, Xiu-Ling Zhao, Xu-Hui Zeng
Summary: This study investigated the reproductive toxicity of acrolein (ACR) and the protective effect of hydrogen sulfide (H2S) in Sertoli cells and germ cells. It was found that ACR caused cell injury and oxidative stress in Sertoli cells, which was prevented by antioxidant treatment. H2S was shown to protect Sertoli cells and germ cells from ACR-induced cell death.
FOOD AND CHEMICAL TOXICOLOGY
(2023)
Article
Pharmacology & Pharmacy
Elif Alan Albayrak, Ozan Mert, Gulcan Demir, Gulnur Sevin
Summary: High-calorie diet, alcohol, and multiple drug use increase reactive oxygen species (ROS) and cause liver damage. Antioxidants have beneficial effects but produce clinically complex results. The hydrogen sulfide (H2S) pathway plays a role in the pathogenesis and treatment of liver diseases. Sildenafil exerts antioxidant and hepatoprotective effects by increasing specific antioxidants and regulating the Keap1/Nrf2 pathway. This study confirms that H2S is a new pharmacological mechanism of action of sildenafil on the liver, suggesting its potential as a therapeutic agent for liver diseases with impaired H2S bioavailability.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Weiwei Gong, Shuping Zhang, Yun Chen, Jieru Shen, Yangyang Zheng, Xiao Liu, Mingxian Zhu, Guoliang Meng
Summary: Diabetic cardiomyopathy lacks effective treatments, but our study showed that H2S deficiency can worsen the condition by promoting oxidative stress, necroptosis, and inflammasome activation. However, supplementation of H2S with sodium hydrosulfide can help alleviate these effects and provide a new therapeutic strategy for diabetic cardiomyopathy.
FREE RADICAL BIOLOGY AND MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Xianli Wang, Shaokun Yu, Yuting Jian, Hongmin Pan, Jiannan Guo, Jian Wu, Wei Guo
Summary: The study found that hydrogen sulfide (H2S) can prevent oxidative stress injury in extravillous trophoblasts by decreasing ROS concentration, maintaining mitochondrial membrane stability, and promoting apoptosis-inhibiting protein expression in cells.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Review
Biochemistry & Molecular Biology
Muhammad Saad Shoaib Khan, Faisal Islam, Yajin Ye, Matthew Ashline, Daowen Wang, Biying Zhao, Zheng Qing Fu, Jian Chen
Summary: Hydrogen sulfide (H2S) plays an important role in signal transduction and adaptive regulation in plants. It improves plant responses to stress conditions by interfering with the cellular redox regulatory network and post-translational modifications of proteins. Additionally, H2S interacts with other gas signals and plant growth regulators to activate multiple signaling pathways.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Oncology
Meng Yu, Weiyan Wang, Jingye Dang, Binghua Liu, Junling Xu, Jingjing Li, Yang Liu, Libo He, Yuling Ying, Jiaxiu Cai, Guohua Cheng, Ke Liu
Summary: Oxidative stress-induced ferroptosis of retinal pigment epithelium (RPE) cells can be attenuated by the antioxidant molecule hydrogen sulfide (H2S). H2S activates the non-canonical NRF2-KEAP1 pathway, stabilizes NRF2, and enhances the interaction between KEAP1 and p62. Moreover, H2S stimulates AMPK to interact and phosphorylate p62, leading to cytoprotective effects against ferroptosis. Targeting the non-canonical NRF2-KEAP1 pathway by H2S-based drugs may hold promise for the treatment of retinal degenerative diseases.
EXPERIMENTAL CELL RESEARCH
(2023)
Article
Plant Sciences
Morteza Soleimani Aghdam, Soumya Mukherjee, Francisco Borja Flores, Marino B. Arnao, Zisheng Luo, Francisco J. Corpas
Summary: Melatonin has important effects on plant growth and development, with antioxidant properties and interactions with plant regulators and reactive oxygen and nitrogen species. Its application in horticultural crops can alleviate stress, delay senescence, and preserve product quality, which is of significant economic importance.
PLANT AND CELL PHYSIOLOGY
(2023)
Review
Plant Sciences
Nishat Parveen, Nidhi Kandhol, Shivesh Sharma, Vijay Pratap Singh, Devendra Kumar Chauhan, Jutta Ludwig-Mueller, Francisco J. Corpas, Durgesh Kumar Tripathi
Summary: The plant hormone auxin plays a crucial role in regulating plant growth and development. Reactive oxygen species (ROS) also serve as signaling molecules at low concentrations, but excessive accumulation of ROS due to environmental stresses can be detrimental to cells. Nitric oxide (NO), a gaseous signaling molecule, has various beneficial effects on plants. Together, auxin, ROS, and NO are involved in developmental processes and abiotic stress tolerance in plants.
PLANT AND CELL PHYSIOLOGY
(2023)
Editorial Material
Biochemistry & Molecular Biology
Luciano Freschi, Francisco J. Corpas, Jose M. Palma
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Plant Sciences
Soumya Mukherjee, Francisco J. Corpas
Summary: Hydrogen peroxide (H2O2) plays a crucial role in modulating root development and architecture under both normal and adverse environmental conditions. Nitric oxide (NO) and hydrogen sulphide (H2S) also have diverse functions in plant development and signaling. Depending on the dosage and application mode, NO and H2S can synergistically or antagonistically mediate H2O2 signaling during root development, thus enhancing tolerance to oxidative stress. This assessment provides a comprehensive update on the cooperative roles of NO and H2S in modulating H2O2 homeostasis during root development, abiotic stress tolerance, and root-microbe interaction.
PLANT CELL AND ENVIRONMENT
(2023)
Review
Plant Sciences
Havza Imtiaz, Anayat Rasool Mir, Francisco J. Corpas, Shamsul Hayat
Summary: Potassium (K+) plays a crucial role in plant homeostasis, and its deficiency significantly impacts photosynthesis and crop production. Under potassium starvation, multiple factors interact to reduce the photosynthetic rate and crop growth. The application of exogenous potassium can improve plant tolerance to abiotic stresses and limit the production of reactive oxygen species through activation of the antioxidant system.
PLANT GROWTH REGULATION
(2023)
Article
Plant Sciences
Shaistul Islam, Sajad Hussain Shah, Francisco J. Corpas, Saud Alamri, Firoz Mohammad
Summary: Salt stress is a common environmental threat to crop growth, development, and productivity. Plant growth regulators (PGRs) play important roles in plant growth and development under various environmental conditions. This study evaluated the efficacy of three selected PGRs (GA(3), SA, and Tria) in alleviating NaCl stress in mustard, and found that SA was the most effective in mitigating the adverse effects of NaCl stress.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2023)
Editorial Material
Plant Sciences
Priya Gahlowt, Durgesh Kumar Tripathi, Francisco J. Corpas, Ravi Gupta, Vijay Pratap Singh
Summary: This study reveals that nitric oxide plays multifaceted roles in plants. It was found that NO produced in the shoot apex leads to S-nitrosation of transcription factor GT-1, which subsequently regulates the expression of the HSFA2 gene, resulting in thermotolerance in Arabidopsis thaliana.
TRENDS IN PLANT SCIENCE
(2023)
Article
Multidisciplinary Sciences
Mohammad Mukarram, M. Masroor A. Khan, Daniel Kurjak, Francisco J. J. Corpas
Summary: Plant susceptibility to salt depends on genetic and physiological factors. In this study, lemongrass plants were treated with chitosan oligomers (COS) to alleviate salinity stress and improve growth and essential oil production. Results showed that COS enhanced photosynthesis, antioxidant defence, stomatal conductance, and overall plant development. The treatment also increased geraniol dehydrogenase activity and lemongrass essential oil production. The findings suggest that COS can be a useful tool for improving crop productivity in saline soil and promoting alternative crops for saline lands.
SCIENTIFIC REPORTS
(2023)
Article
Plant Sciences
Mohammad Mukarram, M. Masroor A. Khan, Daniel Kurjak, Alexander Lux, Francisco J. Corpas
Summary: Lemongrass cultivation is threatened by increasing soil salinity, but silicon nanoparticles (SiNPs) can enhance salt tolerance in lemongrass by minimizing oxidative stress and promoting growth and photosynthetic performance. SiNPs also improve enzymatic antioxidant activity and osmolyte accumulation. In addition, SiNPs enhance oil biosynthesis in lemongrass, making them a useful tool to alleviate salinity stress in lemongrass and related crops.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Salvador Gonzalez-Gordo, Maria A. Munoz-Vargas, Jose M. Palma, Francisco J. Corpas
Summary: The study identified 75 CaPOD genes in sweet pepper based on the existing genome, but only 10 genes were found to be active in the fruit transcriptome. Two genes were upregulated during fruit ripening, seven were downregulated, and one gene was unaffected. Nitric oxide treatment triggered the upregulation of two CaPOD genes while the others were unaffected. In vitro experiments showed that CaPOD IV activity was strongly inhibited by peroxynitrite, NO donors, and reducing agents.
Article
Biochemistry & Molecular Biology
Francisco J. Corpas
Summary: This article discusses the significant change in the perception of hydrogen sulfide (H2S) in living organisms over the past three decades. Once considered toxic, H2S is now recognized as a multifunctional signaling molecule involved in various physiological processes in animal and plant cells. The article introduces a series of research papers highlighting the relevance of H2S in plant and mammalian research, as well as future directions for investigations.
ANTIOXIDANTS & REDOX SIGNALING
(2023)
Article
Chemistry, Physical
Md Atikur Rahman, Yowook Song, Md. Mahadi Hasan, Mohammad Shah Jahan, Manzer H. Siddiqui, Hyung Soo Park, Sang-Hoon Lee, Deepti Singh, Francisco J. Corpas, Ahmad Humayan Kabir, Ki-Won Lee
Summary: The study reveals the mechanistic basis of silicon in enhancing cold stress tolerance in alfalfa plants. Silicon reduces the generation of harmful substances induced by stress, improves photosynthesis and biomass production, and enhances antioxidant capacity by regulating related genes and elemental concentrations.
Article
Environmental Sciences
Jorge de la O-sanchez, Maria A. Munoz-Vargas, Jose M. Palma, Francisco J. Corpas
Summary: This study identified potential LCD isozymes in wild-type Arabidopsis thaliana seedlings and evaluated the impact of nitric oxide (NO) and hydrogen sulfide (H2S) on these isozymes. Results showed that LCD V activity was positively modulated in Atnoa1 mutants and with the application of exogenous H2S.
Article
Plant Sciences
Francisco J. Corpas, Maria A. Munoz-Vargas, Salvador Gonzalez-Gordo, Marta Rodriguez-Ruiz, Jose M. Palma
Summary: This review provides a comprehensive perspective on the metabolism of nitric oxide and hydrogen sulfide in plant cells and discusses the effects of exogenous application of these molecules on maintaining the nutritional quality of horticultural products during storage.
JOURNAL OF PLANT GROWTH REGULATION
(2023)
Article
Biochemistry & Molecular Biology
Nidhi Kandhol, Padmaja Rai, Sangeeta Pandey, Samiksha Singh, Shivesh Sharma, Francisco J. Corpas, Vijay Pratap Singh, Durgesh Kumar Tripathi
Summary: This study investigates the interaction between zinc and cadmium in rice roots and how zinc can protect plants from cadmium stress. The results show that zinc can reduce cadmium accumulation in roots and increase its own accumulation, leading to reduced oxidative stress through modulation of gene expression. These findings are important for improving rice varieties to maintain crop productivity in cadmium-contaminated areas.
