Phenanthrene, but not its isomer anthracene, effectively activates both human and mouse nuclear receptor constitutive androstane receptor (CAR) and induces hepatotoxicity in mice

Title
Phenanthrene, but not its isomer anthracene, effectively activates both human and mouse nuclear receptor constitutive androstane receptor (CAR) and induces hepatotoxicity in mice
Authors
Keywords
Polycyclic Aromatic Hydrocarbons (PAHs), Phenanthrene, Constitutive Androstane Receptor (CAR), Hepatotoxicity
Journal
TOXICOLOGY AND APPLIED PHARMACOLOGY
Volume 378, Issue -, Pages 114618
Publisher
Elsevier BV
Online
2019-06-08
DOI
10.1016/j.taap.2019.114618

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