BPDE and B[a]P induce mitochondrial compromise by ROS-mediated suppression of the SIRT1/TERT/PGC-1α pathway in spermatogenic cells both in vitro and in vivo
BPDE and B[a]P induce mitochondrial compromise by ROS-mediated suppression of the SIRT1/TERT/PGC-1α pathway in spermatogenic cells both in vitro and in vivo
Authors
Keywords
Benzo[, a, ]pyrene, Benzo[, a, ]pyrene-7,8-dihydrodiol-9,10-epoxide, Reactive oxygen species, Mitochondrial damage, Male reproductive toxicity
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