Journal
BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY
Volume 31, Issue -, Pages 82-87Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.bpobgyn.2015.11.010
Keywords
mesenchymal stem cells; multipotent mesenchymal stromal cells; foetal stem cells; perinatal stem cells; osteogenesis imperfecta
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Funding
- Vinnova [2010-00501]
- Swedish Research Council [921-2014-7209]
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Finding suitable cell sources is one of the main challenges in regenerative medicine. In addition to improving the dysfunctional tissue requiring reconstruction, low immunogenicity is beneficial. Mesenchymal stem cells (MSCs) are immune-privileged multi potent stromal cells that can easily multiply and differentiate along many lineages with a minimal oncogenic risk. MSC5 derived from foetal tissues present characteristics that suggest an even stronger cell therapeutic potential in comparison to adult MSC5. Due to these characteristics, they have been and are currently being tested in clinical trials for a diverse variety of disorders. (C) 2015 Elsevier Ltd. All rights reserved.
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