Therapeutic blockade of activin-A improves NK cell function and antitumor immunity

The Emergence of Natural Killer Cells as a Major Target in Cancer Immunotherapy

(2019) Fernando Souza-Fonseca-Guimaraes et al.   TRENDS IN IMMUNOLOGY

Universal Solid-Phase Protein Preparation (USP3) for bottom-up and top-down proteomics

(2019) Laura F. Dagley et al.   JOURNAL OF PROTEOME RESEARCH

Decreased TGFBR3/betaglycan expression enhances the metastatic abilities of renal cell carcinoma cells through TGF-β-dependent and -independent mechanisms

(2018) Jun Nishida et al.   ONCOGENE

New function of the myostatin/activin type I receptor (ALK4) as a mediator of muscle atrophy and muscle regeneration

(2017) Svitlana Pasteuning-Vuhman et al.   FASEB JOURNAL

Cell cycle progression dictates the requirement for BCL2 in natural killer cell survival

(2017) Charlotte Viant et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Paracrine Activin-A Signaling Promotes Melanoma Growth and Metastasis through Immune Evasion

(2017) Prudence Donovan et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

TGF-β participates choroid neovascularization through Smad2/3-VEGF/TNF-α signaling in mice with Laser-induced wet age-related macular degeneration

(2017) Xiaolei Wang et al.   Scientific Reports

Activin promotes skin carcinogenesis by attraction and reprogramming of macrophages

(2016) Maria Antsiferova et al.   EMBO Molecular Medicine

The Helix-Loop-Helix Protein ID2 Governs NK Cell Fate by Tuning Their Sensitivity to Interleukin-15

(2016) Rebecca B. Delconte et al.   IMMUNITY

Transforming Growth Factor-β Signaling Guides the Differentiation of Innate Lymphoid Cells in Salivary Glands

(2016) Victor S. Cortez et al.   IMMUNITY

CIS is a potent checkpoint in NK cell–mediated tumor immunity

(2016) Rebecca B Delconte et al.   NATURE IMMUNOLOGY

TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway

(2016) Sébastien Viel et al.   Science Signaling

High circulating activin A level is associated with tumor progression and predicts poor prognosis in lung adenocarcinoma

(2016) Mir Alireza Hoda et al.   Oncotarget

TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway

(2016) Sébastien Viel et al.   Science Signaling

Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8+ T cells that induce GVHD without antileukemic effects

(2015) K. H. Gartlan et al.   BLOOD

Stimulus-dependent differences in signalling regulate epithelial-mesenchymal plasticity and change the effects of drugs in breast cancer cell lines

(2015) Joseph Cursons et al.   Cell Communication and Signaling

Ly49 receptors: evolution, genetic diversity, and impact on immunity

(2015) Mir Munir A. Rahim et al.   IMMUNOLOGICAL REVIEWS

Invasion of ovarian cancer cells is induced byPITX2-mediated activation of TGF-β and Activin-A

(2015) Moitri Basu et al.   Molecular Cancer

NK cells require IL-28R for optimal in vivo activity

(2015) Fernando Souza-Fonseca-Guimaraes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The IMiDs targets IKZF-1/3 and IRF4 as novel negative regulators of NK cell-activating ligands expression in multiple myeloma

(2015) Cinzia Fionda et al.   Oncotarget

Peripheral natural killer cell maturation depends on the transcription factor Aiolos

(2014) M. L. Holmes et al.   EMBO JOURNAL

TRAIL+ NK Cells Control CD4+ T Cell Responses during Chronic Viral Infection to Limit Autoimmunity

(2014) Iona S. Schuster et al.   IMMUNITY

Differential Requirement for Nfil3 during NK Cell Development

(2014) C. Seillet et al.   JOURNAL OF IMMUNOLOGY

Accurate Protein Complex Retrieval by Affinity Enrichment Mass Spectrometry (AE-MS) Rather than Affinity Purification Mass Spectrometry (AP-MS)

(2014) Eva C. Keilhauer et al.   MOLECULAR & CELLULAR PROTEOMICS

Antigen affinity, costimulation, and cytokine inputs sum linearly to amplify T cell expansion

(2014) J. M. Marchingo et al.   SCIENCE

Innate immunodeficiency following genetic ablation of Mcl1 in natural killer cells

(2014) Priyanka Sathe et al.   Nature Communications

Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells

(2014) Dorothy K Sojka et al.   eLife

Killer Immunoglobulin-like Receptors and Tumor Immunity

(2014) D. M. Benson et al.   Cancer Immunology Research

A2Ablockade enhances anti-metastatic immune responses

(2014) Paul A Beavis et al.   OncoImmunology

Regulation of Ligands for the NKG2D Activating Receptor

(2013) David H. Raulet et al.   Annual Review of Immunology

Blockade of A2Areceptors potently suppresses the metastasis of CD73+tumors

(2013) Paul A. Beavis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myeloid TGF-  Responsiveness Promotes Metastases

(2013) F. Souza-Fonseca-Guimaraes et al.   Cancer Discovery

TGF-β – an excellent servant but a bad master

(2012) Lenka Kubiczkova et al.   Journal of Translational Medicine

Activin Receptor Signaling: A Potential Therapeutic Target for Osteoporosis

(2012) Sutada Lotinun et al.   Current Molecular Pharmacology

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

New insights into the mechanisms of activin action and inhibition

(2011) Kelly L. Walton et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Fate mapping analysis of lymphoid cells expressing the NKp46 cell surface receptor

(2011) E. Narni-Mancinelli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity

(2010) X. Liu et al.   BLOOD

Activin-A attenuates several human natural killer cell functions

(2009) N. C. Robson et al.   BLOOD

Activin-A induces regulatory T cells that suppress T helper cell immune responses and protect from allergic airway disease

(2009) Maria Semitekolou et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Activin A Promotes the TGF- -Induced Conversion of CD4+CD25- T Cells into Foxp3+ Induced Regulatory T Cells

(2009) S. Huber et al.   JOURNAL OF IMMUNOLOGY

Exact Calculations of Average Power for the Benjamini-Hochberg Procedure

(2008) Deborah H Glueck et al.  

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY