Journal
REVUE NEUROLOGIQUE
Volume 175, Issue 10, Pages 604-613Publisher
MASSON EDITEUR
DOI: 10.1016/j.neurol.2019.07.013
Keywords
Air pollution; Particulate matter; Epilepsy; Hippocampus; Neurodegenerative disease
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Funding
- Fundacao de Amparo a Pesquisa do Estado de Sao Paulo - Fapesp
- Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior-CAPES
- Conselho Nacional de Desenvolvimento Cienti'fico e Tecnologico-CNPq
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A growing number of studies have shown that exposure to air pollutants such as particulate matter and gases can cause cardiovascular, neurodegenerative and psychiatric diseases. The severity of the changes depends on several factors such as exposure time, age and gender. Inflammation has been considered as one of the main factors associated with the generation of these diseases. Here we present some cellular mechanisms activated by air pollution that may represent risk factors for epilepsy and drug resistance associated to epilepsy. (C) 2019 Elsevier Masson SAS. All rights reserved.
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