Target highlights in CASP13: Experimental target structures through the eyes of their authors

Towards a complete structural deciphering of Type VI secretion system

(2018) Van Son Nguyen et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Contact‐dependent growth inhibition induces high levels of antibiotic‐tolerant persister cells in clonal bacterial populations

(2018) Anirban Ghosh et al.   EMBO JOURNAL

A Completely Reimplemented MPI Bioinformatics Toolkit with a New HHpred Server at its Core

(2018) Lukas Zimmermann et al.   JOURNAL OF MOLECULAR BIOLOGY

Contractile injection systems of bacteriophages and related systems

(2018) Nicholas M. I. Taylor et al.   MOLECULAR MICROBIOLOGY

Functional plasticity of antibacterial EndoU toxins

(2018) Karolina Michalska et al.   MOLECULAR MICROBIOLOGY

Crystal Structure of an Unusual Single-Stranded DNA-Binding Protein Encoded by Staphylococcal Cassette Chromosome Elements

(2018) Ignacio Mir-Sanchis et al.   STRUCTURE

Automated evaluation of quaternary structures from protein crystals

(2018) Spencer Bliven et al.   PLoS Computational Biology

Salmonella Phage S16 Tail Fiber Adhesin Features a Rare Polyglycine Rich Domain for Host Recognition

(2018) Matthew Dunne et al.   STRUCTURE

Programmed Secretion Arrest and Receptor-Triggered Toxin Export during Antibacterial Contact-Dependent Growth Inhibition

(2018) Zachary C. Ruhe et al.   CELL

PCNA-mediated stabilization of E3 ligase RFWD3 at the replication fork is essential for DNA replication

(2018) Yo-Chuen Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis of meiotic telomere attachment to the nuclear envelope by MAJIN-TERB2-TERB1

(2018) James M. Dunce et al.   Nature Communications

Bacteriophage Therapy: Clinical Trials and Regulatory Hurdles

(2018) Lucy L. Furfaro et al.   Frontiers in Cellular and Infection Microbiology

Biallelic mutations in the ubiquitin ligase RFWD3 cause Fanconi anemia

(2017) Kerstin Knies et al.   JOURNAL OF CLINICAL INVESTIGATION

RPA-Mediated Recruitment of the E3 Ligase RFWD3 Is Vital for Interstrand Crosslink Repair and Human Health

(2017) Laura Feeney et al.   MOLECULAR CELL

RFWD3-Mediated Ubiquitination Promotes Timely Removal of Both RPA and RAD51 from DNA Damage Sites to Facilitate Homologous Recombination

(2017) Shojiro Inano et al.   MOLECULAR CELL

Genetic wiring maps of single-cell protein states reveal an off-switch for GPCR signalling

(2017) Markus Brockmann et al.   NATURE

Dissecting the telomere–inner nuclear membrane interface formed in meiosis

(2017) Devon F Pendlebury et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Telomeric TERB1–TRF1 interaction is crucial for male meiosis

(2017) Juanjuan Long et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of a novel antibacterial toxin that exploits elongation factor Tu to cleave specific transfer RNAs

(2017) Karolina Michalska et al.   NUCLEIC ACIDS RESEARCH

The CDI toxin of Yersinia kristensenii is a novel bacterial member of the RNase A superfamily

(2017) Gaëlle Batot et al.   NUCLEIC ACIDS RESEARCH

A rare polyglycine type II-like helix motif in naturally occurring proteins

(2017) Eberhard Warkentin et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

The Architecture of the Anbu Complex Reflects an Evolutionary Intermediate at the Origin of the Proteasome System

(2017) Adrian C.D. Fuchs et al.   STRUCTURE

Using Force to Punch Holes: Mechanics of Contractile Nanomachines

(2017) Maximilian Brackmann et al.   TRENDS IN CELL BIOLOGY

Dissecting the telomere–inner nuclear membrane interface formed in meiosis

(2017) Devon F Pendlebury et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Telomeric TERB1–TRF1 interaction is crucial for male meiosis

(2017) Juanjuan Long et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Pseudomonas aeruginosa Contact-Dependent Growth Inhibition Plays Dual Role in Host-Pathogen Interactions

(2017) Jeffrey A. Melvin et al.   mSphere

KCTD Hetero-oligomers Confer Unique Kinetic Properties on Hippocampal GABA B Receptor-Induced K + Currents

(2016) Thorsten Fritzius et al.   JOURNAL OF NEUROSCIENCE

Structure of the T4 baseplate and its function in triggering sheath contraction

(2016) Nicholas M. I. Taylor et al.   NATURE

Staphylococcal SCCmec elements encode an active MCM-like helicase and thus may be replicative

(2016) Ignacio Mir-Sanchis et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Unraveling the essential role of CysK in CDI toxin activation

(2016) Parker M. Johnson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interbacterial signaling viaBurkholderiacontact-dependent growth inhibition system proteins

(2016) Erin C. Garcia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis for Substrate Selectivity of the E3 Ligase COP1

(2016) Sacha Uljon et al.   STRUCTURE

Staphylococcal SCCmec elements encode an active MCM-like helicase and thus may be replicative

(2016) Ignacio Mir-Sanchis et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Acyl-CoA Dehydrogenase Drives Heat Adaptation by Sequestering Fatty Acids

(2015) Dengke K. Ma et al.   CELL

MAJIN Links Telomeric DNA to the Nuclear Membrane by Exchanging Telomere Cap

(2015) Hiroki Shibuya et al.   CELL

LINC'ing form and function at the nuclear envelope

(2015) Peter Meinke et al.   FEBS LETTERS

An Extended Cyclic Di-GMP Network in the Predatory Bacterium Bdellovibrio bacteriovorus

(2015) Or Rotem et al.   JOURNAL OF BACTERIOLOGY

Contact-Dependent Growth Inhibition (CDI) and CdiB/CdiA Two-Partner Secretion Proteins

(2015) Julia L.E. Willett et al.   JOURNAL OF MOLECULAR BIOLOGY

Modular composition and dynamics of native GABAB receptors identified by high-resolution proteomics

(2015) Jochen Schwenk et al.   NATURE NEUROSCIENCE

Atomic structures of a bactericidal contractile nanotube in its pre- and postcontraction states

(2015) Peng Ge et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural remodeling of bacteriophage T4 and host membranes during infection initiation

(2015) Bo Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Contact-dependent growth inhibition toxins exploit multiple independent cell-entry pathways

(2015) Julia L. E. Willett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recombination, Pairing, and Synapsis of Homologs during Meiosis

(2015) Denise Zickler et al.   Cold Spring Harbor Perspectives in Biology

Meiotic Recombination: The Essence of Heredity

(2015) Neil Hunter   Cold Spring Harbor Perspectives in Biology

Atomic structures of a bactericidal contractile nanotube in its pre- and postcontraction states

(2015) Peng Ge et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Identification and Characterization of KCASH2 and KCASH3, 2 Novel Cullin3 Adaptors Suppressing Histone Deacetylase and Hedgehog Activity in Medulloblastoma

(2015) Enrico De Smaele et al.   NEOPLASIA

DISOPRED3: precise disordered region predictions with annotated protein-binding activity

(2014) David T. Jones et al.   BIOINFORMATICS

The TRF1-binding protein TERB1 promotes chromosome movement and telomere rigidity in meiosis

(2014) Hiroki Shibuya et al.   NATURE CELL BIOLOGY

WDSPdb: a database for WD40-repeat proteins

(2014) Yang Wang et al.   NUCLEIC ACIDS RESEARCH

Enhancement of fermentable sugar yields by α-xylosidase supplementation of commercial cellulases

(2013) Dina Jabbour et al.   Biotechnology for Biofuels

The carbohydrate-active enzymes database (CAZy) in 2013

(2013) Vincent Lombard et al.   NUCLEIC ACIDS RESEARCH

The Ubiquitin Code

(2012) David Komander et al.   Annual Review of Biochemistry

Polymorphic toxin systems: Comprehensive characterization of trafficking modes, processing, mechanisms of action, immunity and ecology using comparative genomics

(2012) Dapeng Zhang et al.   Biology Direct

Opposite Effects of KCTD Subunit Domains on GABABReceptor-mediated Desensitization

(2012) Riad Seddik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Enzymology ofCellvibrio japonicusAgd31B Protein Reveals α-Transglucosylase Activity in Glycoside Hydrolase Family 31

(2012) Johan Larsbrink et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis of toxicity and immunity in contact-dependent growth inhibition (CDI) systems

(2012) R. P. Morse et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacteriophages and their Implications on Future Biotechnology: A Review

(2012) Irshad UL Haq et al.   Virology Journal

Discrete Cyclic di-GMP-Dependent Control of Bacterial Predation versus Axenic Growth in Bdellovibrio bacteriovorus

(2012) Laura Hobley et al.   PLoS Pathogens

The gp38 Adhesins of the T4 Superfamily: A Complex Modular Determinant of the Phage’s Host Specificity

(2011) Sabrina N. Trojet et al.   Genome Biology and Evolution

Biochemical and Molecular Characterization of Secreted α-Xylosidase fromAspergillus niger

(2011) John S. Scott-Craig et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CRISPR/Cas System and Its Role in Phage-Bacteria Interactions

(2010) Hélène Deveau et al.   Annual Review of Microbiology

Native GABAB receptors are heteromultimers with a family of auxiliary subunits

(2010) Jochen Schwenk et al.   NATURE

Structure of the bacteriophage T4 long tail fiber receptor-binding tip

(2010) S. G. Bartual et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage

(2010) X. Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Morphogenesis of the T4 tail and tail fibers

(2010) Petr G Leiman et al.   Virology Journal

Type VI secretion apparatus and phage tail-associated protein complexes share a common evolutionary origin

(2009) P. G. Leiman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glyphosate: a once-in-a-century herbicide

(2008) Stephen O Duke et al.   PEST MANAGEMENT SCIENCE