Cell division rates decrease with age, providing a potential explanation for the age-dependent deceleration in cancer incidence

Role of stem-cell divisions in cancer risk

(2017) Cristian Tomasetti et al.   NATURE

On the slope of the regression between stem cell divisions and cancer risk, and the lack of correlation between stem cell divisions and environmental factors-associated cancer risk

(2017) Cristian Tomasetti et al.   PLoS One

Stem cell divisions, somatic mutations, cancer etiology, and cancer prevention

(2017) Cristian Tomasetti et al.   SCIENCE

Analysis of cancer genomes reveals basic features of human aging and its role in cancer development

(2016) Dmitriy I. Podolskiy et al.   Nature Communications

Do Mutational Dynamics in Stem Cells Explain the Origin of Common Cancers?

(2015) Gerry P. Crossan et al.   Cell Stem Cell

Cancer risk: Role of environment--Response

(2015) C. Tomasetti et al.   SCIENCE

Variation in cancer risk among tissues can be explained by the number of stem cell divisions

(2015) C. Tomasetti et al.   SCIENCE

Restoring Systemic GDF11 Levels Reverses Age-Related Dysfunction in Mouse Skeletal Muscle

(2014) M. Sinha et al.   SCIENCE

Tissue resident stem cells: till death do us part

(2013) Hadas Raveh-Amit et al.   BIOGERONTOLOGY

A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing

(2013) Maria Carolina Florian et al.   NATURE

Half or more of the somatic mutations in cancers of self-renewing tissues originate prior to tumor initiation

(2013) C. Tomasetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Origin and Evolution of Mutations in Acute Myeloid Leukemia

(2012) John S. Welch et al.   CELL

Identifying the Stem Cell of the Intestinal Crypt: Strategies and Pitfalls

(2012) Nick Barker et al.   Cell Stem Cell

Corrections to: ‘‘Age distribution of cancer in mice’’

(2010) Charles Harding et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Epidermal stem cells are retained in vivo throughout skin aging

(2008) Adam Giangreco et al.   AGING CELL