System analysis of cross-talk between nuclear receptors reveals an opposite regulation of the cell cycle by LXR and FXR in human HepaRG liver cells

Distinct gene regulatory programs define the inhibitory effects of liver X receptors and PPARG on cancer cell proliferation

(2016) Daniel Savic et al.   Genome Medicine

The emerging roles of liver X receptors and their ligands in cancer

(2015) Chin-Yo Lin et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Self-renewing diploid Axin2+ cells fuel homeostatic renewal of the liver

(2015) Bruce Wang et al.   NATURE

Farnesoid X receptor signal is involved in deoxycholic acid-induced intestinal metaplasia of normal human gastric epithelial cells

(2015) SHU LI et al.   ONCOLOGY REPORTS

Hepatocyte-specific deletion of farnesoid X receptor delays but does not inhibit liver regeneration after partial hepatectomy in mice

(2012) Prachi Borude et al.   HEPATOLOGY

Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR

(2012) Anna C. Calkin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Liver Progenitor Cell Line HepaRG Differentiated in a Bioartificial Liver Effectively Supplies Liver Support to Rats with Acute Liver Failure

(2012) Geert A. A. Nibourg et al.   PLoS One

The human hepatocyte cell lines IHH and HepaRG: models to study glucose, lipid and lipoprotein metabolism

(2012) Carolina Huaman Samanez et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

APOBEC3A can activate the DNA damage response and cause cell-cycle arrest

(2011) Sébastien Landry et al.   EMBO REPORTS

Liver X Receptors Inhibit Macrophage Proliferation through Downregulation of Cyclins D1 and B1 and Cyclin-Dependent Kinases 2 and 4

(2011) M. Pascual-Garcia et al.   JOURNAL OF IMMUNOLOGY

Genome-Wide Profiling of Liver X Receptor, Retinoid X Receptor, and Peroxisome Proliferator-Activated Receptor   in Mouse Liver Reveals Extensive Sharing of Binding Sites

(2011) M. Boergesen et al.   MOLECULAR AND CELLULAR BIOLOGY

Comparative Gene Expression Profiles Induced by PPARγ and PPARα/γ Agonists in Human Hepatocytes

(2011) Alexandra Rogue et al.   PLoS One

Nuclear bile acid receptor FXR in the hepatic regeneration

(2010) Wei-Dong Chen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Polyploidy and liver proliferation: Central role of insulin signaling

(2010) Séverine Celton-Morizur et al.   CELL CYCLE

A Comparison of Whole Genome Gene Expression Profiles of HepaRG Cells and HepG2 Cells to Primary Human Hepatocytes and Human Liver Tissues

(2010) S. N. Hart et al.   DRUG METABOLISM AND DISPOSITION

Inhibitory effect of LXR activation on cell proliferation and cell cycle progression through lipogenic activity

(2010) Kang Ho Kim et al.   JOURNAL OF LIPID RESEARCH

Profiling of promoter occupancy by PPARα in human hepatoma cells via ChIP-chip analysis

(2010) David L. M. van der Meer et al.   NUCLEIC ACIDS RESEARCH

Genome-wide tissue-specific farnesoid X receptor binding in mouse liver and intestine

(2009) Ann M. Thomas et al.   HEPATOLOGY

Down-regulation of the LXR transcriptome provides the requisite cholesterol levels to proliferating hepatocytes

(2009) Giuseppe Lo Sasso et al.   HEPATOLOGY

LXR Regulates Cholesterol Uptake Through Idol-Dependent Ubiquitination of the LDL Receptor

(2009) Noam Zelcer et al.   SCIENCE

FXR: a metabolic regulator and cell protector

(2008) Yan-Dong Wang et al.   CELL RESEARCH

Tbx3 controls the fate of hepatic progenitor cells in liver development by suppressing p19ARF expression

(2008) A. Suzuki et al.   DEVELOPMENT

Farnesoid X receptor antagonizes nuclear factor κB in hepatic inflammatory response

(2008) Yan-Dong Wang et al.   HEPATOLOGY