Intrinsically disordered proteins and structured proteins with intrinsically disordered regions have different functional roles in the cell

The evolutionary origins of cell type diversification and the role of intrinsically disordered proteins

(2018) Karl J Niklas et al.   JOURNAL OF EXPERIMENTAL BOTANY

Intrinsically Disordered Proteins Link Alternative Splicing and Post-translational Modifications to Complex Cell Signaling and Regulation

(2018) Jianhong Zhou et al.   JOURNAL OF MOLECULAR BIOLOGY

Intrinsic Disorder and Posttranslational Modifications: The Darker Side of the Biological Dark Matter

(2018) April L. Darling et al.   Frontiers in Genetics

Extreme disorder in an ultrahigh-affinity protein complex

(2018) Alessandro Borgia et al.   NATURE

Intrinsically Disordered Proteins: The Dark Horse of the Dark Proteome

(2018) Prakash Kulkarni et al.   PROTEOMICS

MobiDB 3.0: more annotations for intrinsic disorder, conformational diversity and interactions in proteins

(2017) Damiano Piovesan et al.   NUCLEIC ACIDS RESEARCH

The contribution of intrinsically disordered regions to protein function, cellular complexity, and human disease

(2016) M. Madan Babu   BIOCHEMICAL SOCIETY TRANSACTIONS

UniProt: the universal protein knowledgebase

(2016)   NUCLEIC ACIDS RESEARCH

PANTHER version 11: expanded annotation data from Gene Ontology and Reactome pathways, and data analysis tool enhancements

(2016) Huaiyu Mi et al.   NUCLEIC ACIDS RESEARCH

Large-scale analysis of intrinsic disorder flavors and associated functions in the protein sequence universe

(2016) Marco Necci et al.   PROTEIN SCIENCE

Resolving the ambiguity: Making sense of intrinsic disorder when PDB structures disagree

(2016) Shelly DeForte et al.   PROTEIN SCIENCE

Intrinsic Disorder in Transmembrane Proteins: Roles in Signaling and Topology Prediction

(2016) Jérôme Bürgi et al.   PLoS One

Functional roles of transiently and intrinsically disordered regions within proteins

(2015) Vladimir N. Uversky   FEBS Journal

Intrinsically disordered proteins in cellular signalling and regulation

(2015) Peter E. Wright et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

PANTHER version 10: expanded protein families and functions, and analysis tools

(2015) Huaiyu Mi et al.   NUCLEIC ACIDS RESEARCH

Intrinsically Disordered Proteins and Intrinsically Disordered Protein Regions

(2014) Christopher J. Oldfield et al.   Annual Review of Biochemistry

Exceptionally abundant exceptions: comprehensive characterization of intrinsic disorder in all domains of life

(2014) Zhenling Peng et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Pathological Unfoldomics of Uncontrolled Chaos: Intrinsically Disordered Proteins and Human Diseases

(2014) Vladimir N. Uversky et al.   CHEMICAL REVIEWS

The triple power of D³: Protein intrinsic disorder in degenerative diseases

(2014) Vladimir Uversky   Frontiers in Bioscience-Landmark

The structural and functional signatures of proteins that undergo multiple events of post-translational modification

(2014) Vikas Pejaver et al.   PROTEIN SCIENCE

Intrinsically Disordered Segments Affect Protein Half-Life in the Cell and during Evolution

(2014) Robin van der Lee et al.   Cell Reports

RAPID: Fast and accurate sequence-based prediction of intrinsic disorder content on proteomic scale

(2013) Jing Yan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Under-folded proteins: Conformational ensembles and their roles in protein folding, function, and pathogenesis

(2013) Vladimir N. Uversky   BIOPOLYMERS

Alternative splicing of intrinsically disordered regions and rewiring of protein interactions

(2013) Marija Buljan et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Large-scale gene function analysis with the PANTHER classification system

(2013) Huaiyu Mi et al.   Nature Protocols

Distinct Types of Disorder in the Human Proteome: Functional Implications for Alternative Splicing

(2013) Recep Colak et al.   PLoS Computational Biology

Protein disorder—a breakthrough invention of evolution?

(2011) Avner Schlessinger et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Stochastic theory of nonequilibrium steady states and its applications. Part I

(2011) Xue-Juan Zhang et al.   PHYSICS REPORTS-REVIEW SECTION OF PHYSICS LETTERS

Bringing order to protein disorder through comparative genomics and genetic interactions

(2011) Jeremy Bellay et al.   GENOME BIOLOGY

Understanding protein non-folding

(2010) Vladimir N. Uversky et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Verification of alternative splicing variants based on domain integrity, truncation length and intrinsic protein disorder

(2010) Hedi Hegyi et al.   NUCLEIC ACIDS RESEARCH

Close encounters of the third kind: disordered domains and the interactions of proteins

(2009) Peter Tompa et al.   BIOESSAYS

Unfoldomics of human diseases: linking protein intrinsic disorder with diseases

(2009) Vladimir N Uversky et al.   BMC GENOMICS

The Mysterious Unfoldome: Structureless, Underappreciated, Yet Vital Part of Any Given Proteome

(2009) Vladimir N. Uversky   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Intrinsically Disordered Proteins in Human Diseases: Introducing the D2 Concept

(2008) Vladimir N. Uversky et al.   Annual Review of Biophysics

The unfoldomics decade: an update on intrinsically disordered proteins

(2008) A Keith Dunker et al.   BMC GENOMICS

Role of intrinsically disordered protein regions/domains in transcriptional regulation

(2008) Anna S. Garza et al.   LIFE SCIENCES

Tight Regulation of Unstructured Proteins: From Transcript Synthesis to Protein Degradation

(2008) J. Gsponer et al.   SCIENCE