Journal
PHYTOTHERAPY RESEARCH
Volume 33, Issue 11, Pages 2904-2917Publisher
WILEY
DOI: 10.1002/ptr.6478
Keywords
food-derived applications; health promotion; phytopharmacological potential; Stevia rebaudiana Bertoni
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Funding
- CONICYT PIA/APOYO CCTE [AFB170007]
- national funds through FCT/MCTES (PIDDAC)
- Portuguese Foundation for Science and Technology (FCT-Portugal) [UID/BIM/04293/2013, NORTE-01-0145-FEDER-000012]
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Stevia rebaudiana Bertoni, a plant from South America and indigenous of Paraguay, has shown several biological effects and healthy properties, although it is especially used in South America and some Asiatic regions. In addition, it is a natural sweetener, almost 300 times sweeter than sucrose, being attributed to its phytoconstituents prominent antioxidant, antimicrobial, antidiabetic (antihyperglycemic, insulinotropic, and glucagonostatic), antiplatelet, anticariogenic, and antitumor effects. In this sense, this work aims to provide an extensive overview on the historical practices of stevia and its effects in human health based on its chemical composition and applications for both food and pharmaceutical industries.
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