ROR1 and ROR2—novel targets for neuroblastoma

Phase I Trial: Cirmtuzumab Inhibits ROR1 Signaling and Stemness Signatures in Patients with Chronic Lymphocytic Leukemia

(2018) Michael Y. Choi et al.   Cell Stem Cell

Adoptive immunotherapy with haploidentical natural killer cells and Anti-GD2 monoclonal antibody m3F8 for resistant neuroblastoma: Results of a phase I study

(2018) Shakeel Modak et al.   OncoImmunology

Analysis of ROR1 Protein Expression in Human Cancer and Normal Tissues

(2016) Ashwini Balakrishnan et al.   CLINICAL CANCER RESEARCH

Expression of ROR1 has prognostic significance in triple negative breast cancer

(2016) Hui-Ping Chien et al.   VIRCHOWS ARCHIV

Wnt5a induces ROR1/ROR2 heterooligomerization to enhance leukemia chemotaxis and proliferation

(2015) Jian Yu et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting the ROR1 and ROR2 receptors in epithelial ovarian cancer inhibits cell migration and invasion

(2015) Claire Henry et al.   Oncotarget

Silencing of Receptor Tyrosine Kinase ROR1 Inhibits Tumor-Cell Proliferation via PI3K/AKT/mTOR Signaling Pathway in Lung Adenocarcinoma

(2015) Yanchun Liu et al.   PLoS One

IGF1R- and ROR1-Specific CAR T Cells as a Potential Therapy for High Risk Sarcomas

(2015) Xin Huang et al.   PLoS One

Ovarian cancer stem cells express ROR1, which can be targeted for anti–cancer-stem-cell therapy

(2014) Suping Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ROR1 expression correlated with poor clinical outcome in human ovarian cancer

(2014) Huilin Zhang et al.   Scientific Reports

Targeting ROR1 Inhibits Epithelial-Mesenchymal Transition and Metastasis

(2013) B. Cui et al.   CANCER RESEARCH

NKX2-1/TITF1/TTF-1-Induced ROR1 Is Required to Sustain EGFR Survival Signaling in Lung Adenocarcinoma

(2012) Tomoya Yamaguchi et al.   CANCER CELL

Targeting malignant B cells with an immunotoxin against ROR1

(2012) Sivasubramanian Baskar et al.   mAbs

Children's Oncology Group's 2013 blueprint for research: Neuroblastoma

(2012) Julie R. Park et al.   PEDIATRIC BLOOD & CANCER

ROR1 Is Expressed in Human Breast Cancer and Associated with Enhanced Tumor-Cell Growth

(2012) Suping Zhang et al.   PLoS One

Restricted Cell Surface Expression of Receptor Tyrosine Kinase ROR1 in Pediatric B-Lineage Acute Lymphoblastic Leukemia Suggests Targetability with Therapeutic Monoclonal Antibodies

(2012) Hema Dave et al.   PLoS One

Therapeutic Potential and Challenges of Targeting Receptor Tyrosine Kinase ROR1 with Monoclonal Antibodies in B-Cell Malignancies

(2011) Jiahui Yang et al.   PLoS One

Anti-GD2 Antibody with GM-CSF, Interleukin-2, and Isotretinoin for Neuroblastoma

(2010) Alice L. Yu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Long-Term Results for Children With High-Risk Neuroblastoma Treated on a Randomized Trial of Myeloablative Therapy Followed by 13-cis-Retinoic Acid: A Children's Oncology Group Study

(2009) Katherine K. Matthay et al.   JOURNAL OF CLINICAL ONCOLOGY

RNAi screen for rapid therapeutic target identification in leukemia patients

(2009) J. W. Tyner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unique Cell Surface Expression of Receptor Tyrosine Kinase ROR1 in Human B-Cell Chronic Lymphocytic Leukemia

(2008) S. Baskar et al.   CLINICAL CANCER RESEARCH

High-dose rapid and standard induction chemotherapy for patients aged over 1 year with stage 4 neuroblastoma: a randomised trial

(2008) Andrew DJ Pearson et al.   LANCET ONCOLOGY