Journal
ORGANIC LETTERS
Volume 21, Issue 19, Pages 8053-8057Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.9b03031
Keywords
-
Categories
Funding
- National Science Foundation [CHE-1414458, CHE-1726077]
- Virginia Tech graduate school
Ask authors/readers for more resources
A method for the preparation of air stable difluoroboryl acrylamides is reported. In contrast to the ubiquitous organotrifluoroborate salts, difluoroboryl acrylamides are relatively nonpolar and are readily purified by silica chromatography. Difluoroboryl acrylamides serve as efficient substrates in cross-coupling reactions to afford the corresponding trisubstituted acrylamides in good to excellent yields. The utility of the difluoroboryl group in various chemical transformations is presented.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available