DREAM and RB cooperate to induce gene repression and cell-cycle arrest in response to p53 activation

Revealing a human p53 universe

(2018) Thuy-Ai T Nguyen et al.   NUCLEIC ACIDS RESEARCH

The cell cycle regulatory DREAM complex is disrupted by high expression of oncogenic B-Myb

(2018) Audra N. Iness et al.   ONCOGENE

MDM2-mediated degradation of WRN promotes cellular senescence in a p53-independent manner

(2018) Boya Liu et al.   ONCOGENE

Census and evaluation of p53 target genes

(2017) M Fischer   ONCOGENE

Conservation and divergence of C-terminal domain structure in the retinoblastoma protein family

(2017) Tyler J. Liban et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The DREAM complex through its subunit Lin37 cooperates with Rb to initiate quiescence

(2017) Christina FS Mages et al.   eLife

Structural Conservation and E2F Binding Specificity within the Retinoblastoma Pocket Protein Family

(2016) Tyler J. Liban et al.   JOURNAL OF MOLECULAR BIOLOGY

Treating cancer with selective CDK4/6 inhibitors

(2016) Ben O'Leary et al.   Nature Reviews Clinical Oncology

Integration of TP53, DREAM, MMB-FOXM1 and RB-E2F target gene analyses identifies cell cycle gene regulatory networks

(2016) Martin Fischer et al.   NUCLEIC ACIDS RESEARCH

Structural basis for LIN54 recognition of CHR elements in cell cycle-regulated promoters

(2016) Aimee H. Marceau et al.   Nature Communications

Dynamics of CDKN1A in Single Cells Defined by an Endogenous Fluorescent Tagging Toolkit

(2016) Jacob Stewart-Ornstein et al.   Cell Reports

Structural mechanisms of DREAM complex assembly and regulation

(2015) Keelan Z. Guiley et al.   GENES & DEVELOPMENT

The transcription factor p53: Not a repressor, solely an activator

(2014) Martin Fischer et al.   CELL CYCLE

Loss of the Mammalian DREAM Complex Deregulates Chondrocyte Proliferation

(2014) C. Forristal et al.   MOLECULAR AND CELLULAR BIOLOGY

The CHR site: definition and genome-wide identification of a cell cycle transcriptional element

(2014) Gerd A. Müller et al.   NUCLEIC ACIDS RESEARCH

A multi-split mapping algorithm for circular RNA, splicing, trans-splicing and fusion detection

(2014) Steve Hoffmann et al.   GENOME BIOLOGY

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity

(2013) F. Ann Ran et al.   CELL

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

p53-dependent gene repression through p21 is mediated by recruitment of E2F4 repression complexes

(2013) E K Benson et al.   ONCOGENE

p53 can repress transcription of cell cycle genes through a p21WAF1/CIP1-dependent switch from MMB to DREAM protein complex binding at CHR promoter elements

(2012) Marianne Quaas et al.   CELL CYCLE

Regulation of transcription and chromatin structure by pRB: Here, there and everywhere

(2012) Srikanth Talluri et al.   CELL CYCLE

Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems

(2012) Oktay Tacar et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

The CHR promoter element controls cell cycle-dependent gene transcription and binds the DREAM and MMB complexes

(2011) Gerd A. Müller et al.   NUCLEIC ACIDS RESEARCH

Dissecting the Unique Role of the Retinoblastoma Tumor Suppressor during Cellular Senescence

(2010) Agustin Chicas et al.   CANCER CELL

B-MYB Is Required for Recovery from the DNA Damage-Induced G2 Checkpoint in p53 Mutant Cells

(2009) M. Mannefeld et al.   CANCER RESEARCH

Nutlin-3 Affects Expression and Function of Retinoblastoma Protein

(2009) Wei Du et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Rb2/p130 is the dominating pocket protein in the p53–p21 DNA damage response pathway leading to senescence

(2009) H Helmbold et al.   ONCOGENE

Accurate whole human genome sequencing using reversible terminator chemistry

(2008) David R. Bentley et al.   NATURE

Transcriptional activation of the tumor suppressor and differentiation gene S100A2 by a novel p63-binding site

(2008) Ralf D. Kirschner et al.   NUCLEIC ACIDS RESEARCH