Article
Agriculture, Dairy & Animal Science
Zolzaya Byambajav, Erdenebat Bulgan, Yuji Hirai, Momoko Nakayama, Misaki Tanaka, Yurika Nitta, Akio Suzuki, Takashi Umemura, Bold Altankhuu, Alimaa Tsagaan, Batbaatar Vanaabaatar, Erdenebaatar Janchivdorj, Nyam-Osor Purevdorj, Narantuya Ayushjav, Takeshi Yamasaki, Motohiro Horiuchi
Summary: This study isolated and characterized Campylobacter spp. from chickens in Mongolia, finding resistance to multiple antibiotics. Some C. jejuni/C. coli isolates were resistant to nalidixic acid and fluoroquinolones, with specific genetic mechanisms for resistance identified. Multilocus sequence typing and phylogenetic analyses revealed genetic variation and potential links to other countries. This study represents the first report on antimicrobial resistance of Campylobacter spp. in farm animals in Mongolia, providing valuable insights for antibiotic use in this region.
Article
Public, Environmental & Occupational Health
Rima D. Shrestha, Agnes Agunos, Sheryl P. Gow, Csaba Varga
Summary: This study investigated antimicrobial resistance in turkeys in Canada and found a high prevalence of resistant Campylobacter isolates. Despite minimal use of tetracyclines and fluoroquinolones, a significant proportion of C. jejuni and C. coli isolates exhibited resistance to these drugs. Regional differences in resistance prevalence were observed, and certain antimicrobial classes may have contributed to the maintenance of resistance.
EPIDEMIOLOGY AND INFECTION
(2023)
Article
Agriculture, Dairy & Animal Science
T. S. Dias, R. J. Nascimento, L. S. Machado, D. L. C. Abreu, E. R. do Nascimento, V. L. A. Pereira, M. H. C. de Aquino
Summary: The study revealed that Campylobacter spp. from conventional poultry production showed higher resistance to antibiotics compared to those from backyard poultry flocks, particularly in terms of amoxicillin with clavulanic acid, ceftiofur, erythromycin, and tetracycline. Additionally, a higher frequency of resistance to fluoroquinolones was observed in strains from both rearing systems, indicating the spread of resistant strains in poultry production environments.
BRITISH POULTRY SCIENCE
(2021)
Article
Infectious Diseases
Bernd-Alois Tenhagen, Matthias Flor, Katja Alt, Marie-Theres Knuever, Christiane Buhler, Annemarie Kaesbohrer, Kerstin Stingl
Summary: The study investigated trends in antimicrobial resistance in Campylobacter jejuni and Campylobacter coli in poultry in Germany between 2010 and 2016, finding higher resistance in C. coli than in C. jejuni, and higher resistance in turkeys than in broilers. Resistance was highest to tetracycline and (fluoro)quinolones, with lower resistance to gentamicin and erythromycin. While resistance to tetracycline and erythromycin decreased over time, resistance to (fluoro)quinolones increased. An association between antimicrobial use and resistance was observed for tetracycline and erythromycin, but not for aminoglycosides. Nalidixic acid and ciprofloxacin resistance increased despite a decrease in fluoroquinolone use, suggesting other factors influencing resistance to (fluoro)quinolones in Campylobacter.
Article
Biochemistry & Molecular Biology
Khaloud M. Alarjani, Manal F. Elkhadragy, Abdulrahman H. Al-Masoud, Hany M. Yehia
Summary: Campylobacter jejuni and Salmonella typhimurium are leading causes of bacterial food contamination in chicken carcasses. This study isolated these bacteria from chicken carcass samples in Riyadh, Saudi Arabia, and identified them using phenotypic and genetic methods. The isolates showed multidrug resistance, and the identification was successful using specific molecular sizes and gene sequencing.
BIOSCIENCE REPORTS
(2021)
Article
Microbiology
Amal Awad, Hung-Yueh Yeh, Hazem Ramadan, Michael J. Rothrock
Summary: This study aimed to investigate the genetic relatedness, antibiotic resistance, and virulence determinants of thermophilic Campylobacter isolates from pasture-raised poultry farms in the southeastern United States. It was found that Campylobacter isolates from these farms showed genetic relatedness to isolates commonly associated with humans, indicating the potential for transmission of antibiotic-resistant and pathogenic strains from pasture-raised broiler flocks to humans.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Microbiology
Nicolle Lima Barbieri, Ramon Loureiro Pimenta, Dayanne Araujo de Melo, Lisa K. Nolan, Miliane Moreira Soares de Souza, Catherine M. Logue
Summary: This study examined the presence of mcr genes in 107 E. coli isolates from production poultry in Brazil, revealing a high prevalence of mcr-1 in 62 isolates. Additional analyses such as plasmid replicon typing and antimicrobial resistance phenotype characterization were conducted for further understanding. The findings suggest that the high prevalence of mcr-1 in poultry could potentially pose a threat to antimicrobial resistance in the human food chain.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Agriculture, Dairy & Animal Science
Khyati Bhardwaj, Suchitra M. Shenoy, Shrikala Baliga, B. Unnikrishnan, B. Shantharam Baliga, Vasanth Kumar Shetty
Summary: The study conducted in poultry farms of coastal Southern Karnataka, India, found high levels of antibiotic resistance in Escherichia coli and Klebsiella pneumoniae isolates, with a focus on resistance to fluoroquinolones and tetracycline. The most common resistance genes detected were qnrB, qnrS, and qnrA, with most isolates showing high MAR indices reflecting widespread antibiotic use.
Article
Food Science & Technology
Seyedeh Bita Mousavinafchi, Ebrahim Rahimi, Amir Shakerian
Summary: This study investigated the antimicrobial resistance patterns, virulence genes, and genetic variation of Campylobacter species obtained from chicken meat samples in Iran. The results showed that these isolates exhibited high resistance to quinolones and tetracycline, had pathogenic potential, and displayed genetic diversity.
FOOD SCIENCE & NUTRITION
(2023)
Article
Food Science & Technology
Shanwei Tong, Luyao Ma, Jennifer Ronholm, William Hsiao, Xiaonan Lu
Summary: Campylobacter is a leading cause of bacterial gastroenteritis worldwide, and whole genome sequencing has been proven to be a robust and efficient tool for monitoring this microbe in food chain surveillance.
CURRENT OPINION IN FOOD SCIENCE
(2021)
Article
Biotechnology & Applied Microbiology
Runan Yan, Nkuchia M. M'ikanatha, Irving Nachamkin, Lauren K. Hudson, Thomas G. Denes, Jasna Kovac
Summary: The prevalence of antimicrobial resistance in Campylobacter isolates from human and meat sources in Pennsylvania was investigated. Resistance to erythromycin was confirmed in 6% of human isolates and 4% of meat isolates, while ciprofloxacin resistance was more common in human isolates. There was a good concordance between phenotypic resistance and the presence of known resistance genetic determinants.
Article
Biochemistry & Molecular Biology
Manel Gharbi, Mohammed Abdo Saghir Abbas, Safa Hamrouni, Abderrazak Maaroufi
Summary: This study reports the first identification of Campylobacter coli strains harboring both aac(6 ')-Ib and aac(6 ')-Ib-cr variants in Tunisia. These genes are present in isolates exhibiting resistance to multiple antibiotics.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Infectious Diseases
Jonathan Bastard, Nguyen Thi Nhung, Vo Be Hien, Bach Tuan Kiet, Laura Temime, Lulla Opatowski, Juan Carrique-Mas, Marc Choisy
Summary: This study aimed to investigate the within-farm and outside-farm drivers of colistin resistance in small-scale chicken farms in the Mekong delta of Vietnam. The results showed that colistin resistance in chickens was mostly affected by importations of resistance, and to a lesser extent, by recent antimicrobial use.
TRANSBOUNDARY AND EMERGING DISEASES
(2022)
Article
Microbiology
Hiroshi Asakura, Shiori Yamamoto, Kazuhiro Yamada, Jun Kawase, Hiromi Nakamura, Kou-ichiro Abe, Yoshimasa Sasaki, Tetsuya Ikeda, Ryohei Nomoto
Summary: Campylobacter jejuni and C. coli are major causes of gastrointestinal illnesses transmitted to humans mainly through chicken meats. This study examined the levels of bacterial contamination in retail chicken meats in Japan and found that 45.7% of the samples were positive, with 8.4% exceeding the safe limit. Bacterial counts were higher in fall compared to spring and summer, and younger slaughtered chickens were more contaminated. The study also identified antimicrobial resistance genes and clonal complexes of C. jejuni isolates.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Veterinary Sciences
George Natsos, Niki K. Mouttotou, Emmanouil Magiorkinis, Anastasios Ioannidis, Maria Magana, Stylianos Chatzipanagiotou, Konstantinos C. Koutoulis
Summary: This study investigated the antimicrobial susceptibility and molecular epidemiology of 205 Campylobacter isolates from Greek poultry flocks, revealing high levels of resistance and genetic diversity, with some isolates potentially being transmitted between farms via personnel or shared equipment. The findings contribute to a better understanding of the molecular epidemiology and antimicrobial resistance of Campylobacter species derived from poultry in Greece.
VETERINARY SCIENCES
(2021)
Article
Veterinary Sciences
Andre J. Rabie, Ian M. McLaren, Mark F. Breslin, Robin Sayers, Rob H. Davies
Article
Agriculture, Dairy & Animal Science
R. J. Gosling, R. H. Davies
BRITISH POULTRY SCIENCE
(2015)
Article
Agriculture, Dairy & Animal Science
V. K. Morris, J. J. Carrique-Mas, D. Mueller-Doblies, R. H. Davies, A. D. Wales, V. M. Allen
BRITISH POULTRY SCIENCE
(2015)
Article
Immunology
R. Davies, R. J. Gosling, A. D. Wales, R. P. Smith
COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES
(2016)
Review
Public, Environmental & Occupational Health
A. D. Wales, R. H. Davies
ZOONOSES AND PUBLIC HEALTH
(2017)
Review
Food Science & Technology
Andrew D. Wales, Ana B. Vidal, Robert H. Davies, John D. Rodgers
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY
(2019)
Article
Microbiology
Rebecca J. Gosling, Doris Mueller-Doblies, Francesca Martelli, Javier Nunez-Garcia, Nick Kell, Andre Rabie, Andy D. Wales, Robert H. Davies
VETERINARY MICROBIOLOGY
(2018)
Review
Food Science & Technology
Robert Davies, Andrew Wales
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY
(2019)
Review
Veterinary Sciences
R. H. Davies, J. R. Lawes, A. D. Wales
JOURNAL OF SMALL ANIMAL PRACTICE
(2019)
Review
Agriculture, Dairy & Animal Science
Andrew Wales, Robert Davies
WORLDS POULTRY SCIENCE JOURNAL
(2020)
Article
Microbiology
Rebecca J. Gosling, Ian Mawhinney, Kurt Richardson, Andrew Wales, Rob Davies
Summary: This study compared the effectiveness of different organic acid feed additive products in reducing Salmonella and avian pathogenic E. coli, finding that Finio had a significant impact while other products had limited effectiveness.
Article
Art
Alastair S. Macdonald, Mark A. Chambers, Roberto La Ragione, Kayleigh Wyles, Matthieu Poyade, Andrew Wales, Naomi Klepacz, Tom R. Kupfer, Fraje Watson, Shona Noble
Summary: This study used visualization methods to enhance awareness of infection-related behaviors during veterinary surgery preparation, leading to behavior change and implementation of infection control measures. The approach also improved the delivery of training content by making complex contamination concepts easier to understand.
Review
Infectious Diseases
Andrew D. Wales, Robert H. Davies
Review
Food Science & Technology
Victor M. Andres, Rob H. Davies
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY
(2015)
Article
Veterinary Sciences
Kriengwich Limpavithayakul, Nataya Charoenvisal, Somsak Pakpinyo
Summary: The PCR-RFLP molecular assay was verified as a convenient technique for detecting the MS-H vaccine strain, and the immune response mechanisms in vaccinated layer-type chickens were characterized. Vaccination stimulated immune response mechanisms in chickens with no significant difference between single and double doses.
Article
Veterinary Sciences
Doan Hoang Phu, Ruethai Narinthorn, Nguyen Thi Nhung, Niwat Chansiripornchai, Patrick J. Blackall, Conny Turni, Juan Carrique-Mas, Thotsapol Thomrongsuwannakij
Summary: Chicken in southern Thailand has different prevalence and resistance patterns of Campylobacter. Commercial broilers exhibit higher resistance to quinolones and lower resistance to macrolides and tetracycline compared to native chickens. Resistance patterns are more consistent within farms, and commercial broilers show higher homogeneity. Phenotypic and genotypic resistance have partial agreement among isolates.
Article
Veterinary Sciences
Sanjiv Kumar, Madhurendu Kumar Gupta, Sanjit Kumar, Tanmoy Rana
Summary: This study evaluated the relative efficacy of allopurinol and febuxostat, two important anti-gout agents, in controlling hyperuricemia/gout using a poultry model. The results showed that both allopurinol and febuxostat have definite potential for ameliorating hyperuricemia and gout in poultry, with febuxostat showing better effects compared to allopurinol.
Article
Veterinary Sciences
Robert Jan Molenaar, Remco Dijkman, Christiaan ter Veen, Annet Heuvelink, Fiona van Kaam, Marieke Augustijn, Anneke Feberwee
Summary: This report describes an outbreak of Salmonella Pullorum (SP) in a Dutch laying flock, causing increased mortality, decreased egg production, and neurological signs. SP was frequently isolated from various organs, and immunostaining showed cerebral granulomas in birds with neurological signs. Vaccination did not affect the detection of SP antibodies. Some clinically healthy birds had ovarian lesions associated with SP contact, but carrier status could not be confirmed. Phylogenetic analysis showed clonality of the SP isolates within the outbreak.
Article
Veterinary Sciences
Yingfei Sun, Yingjie Wang, Lulu Wang, Mengyun Zou, Xiuli Peng
Summary: This study investigates the regulation of miR-33-5p gene expression during MG infection. The researchers found an upregulation in pri-miR-33-5p and pre-miR-33-5p expression, indicating transcriptional regulation. They identified a binding motif for STAT5 in the miR-33-5p promoter element and showed that STAT5 modulates miR-33-5p transcription in response to MG infection. The overexpression of STAT5 led to increased miR-33-5p expression while suppressing JNK1 expression.