Time-dependent dysregulation of autophagy: Implications in aging and mitochondrial homeostasis in the kidney proximal tubule

Mitophagy is primarily due to alternative autophagy and requires the MAPK1 and MAPK14 signaling pathways

(2015) Yuko Hirota et al.   Autophagy

Exploring the origin and limitations of kidney regeneration

(2015) Tomomi Endo et al.   JOURNAL OF PATHOLOGY

The aging kidney revisited: A systematic review

(2014) Davide Bolignano et al.   AGEING RESEARCH REVIEWS

Autophagic Clearance of Mitochondria in the Kidney Copes with Metabolic Acidosis

(2014) T. Namba et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Autophagy and the kidney: health and disease

(2014) Y. Takabatake et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Autophagy-Mediated Tumor Promotion

(2013) Jessie Yanxiang Guo et al.   CELL

The role of mitochondria in aging

(2013) Ana Bratic et al.   JOURNAL OF CLINICAL INVESTIGATION

FOXO3A directs a protective autophagy program in haematopoietic stem cells

(2013) Matthew R. Warr et al.   NATURE

Autophagy in Human Health and Disease

(2013) Augustine M.K. Choi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Autophagy and ageing: Insights from invertebrate model organisms

(2012) Eirini Lionaki et al.   AGEING RESEARCH REVIEWS

Autophagy Guards Against Cisplatin-Induced Acute Kidney Injury

(2012) Atsushi Takahashi et al.   AMERICAN JOURNAL OF PATHOLOGY

Physiological Roles of Mitochondrial Reactive Oxygen Species

(2012) Laura A. Sena et al.   MOLECULAR CELL

Age-related changes in the function of autophagy in rat kidneys

(2011) Jing Cui et al.   AGE

"Autophagic flux" in normal mouse tissues: Focus on endogenous LC3A processing

(2011) Christos E. Zois et al.   Autophagy

Autophagy and Aging

(2011) David C. Rubinsztein et al.   CELL

Autophagy-deficient mice develop multiple liver tumors

(2011) A. Takamura et al.   GENES & DEVELOPMENT

Autophagy Protects the Proximal Tubule from Degeneration and Acute Ischemic Injury

(2011) T. Kimura et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Lower estimated glomerular filtration rate and higher albuminuria are associated with mortality and end-stage renal disease. A collaborative meta-analysis of kidney disease population cohorts

(2011) Brad C. Astor et al.   KIDNEY INTERNATIONAL

The genetics of ageing

(2010) Cynthia J. Kenyon   NATURE

Chemical modulators of autophagy as biological probes and potential therapeutics

(2010) Angeleen Fleming et al.   Nature Chemical Biology

Mitochondrial DNA Mutations Induce Mitochondrial Dysfunction, Apoptosis and Sarcopenia in Skeletal Muscle of Mitochondrial DNA Mutator Mice

(2010) Asimina Hiona et al.   PLoS One

Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease

(2010) M. M. Lipinski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aging: Central role for autophagy and the lysosomal degradative system

(2009) Yogendra S. Rajawat et al.   AGEING RESEARCH REVIEWS

Random Point Mutations with Major Effects on Protein-Coding Genes Are the Driving Force behind Premature Aging in mtDNA Mutator Mice

(2009) Daniel Edgar et al.   Cell Metabolism

Prevalence of chronic kidney disease in the Japanese general population

(2009) Enyu Imai et al.   Clinical and Experimental Nephrology

Mice Deficient in Both Mn Superoxide Dismutase and Glutathione Peroxidase-1 Have Increased Oxidative Damage and a Greater Incidence of Pathology but No Reduction in Longevity

(2009) Y. Zhang et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

(2009) David E. Harrison et al.   NATURE

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

The aging kidney

(2008) Xin J. Zhou et al.   KIDNEY INTERNATIONAL

Autophagy and aging: keeping that old broom working

(2008) Ana Maria Cuervo   TRENDS IN GENETICS