A Natural Product with High Affinity to Sigma and 5-HT7 Receptors as Novel Therapeutic Drug for Negative and Cognitive Symptoms of Schizophrenia

Prenatal one-carbon metabolism dysregulation programs schizophrenia-like deficits

(2017) A Alachkar et al.   MOLECULAR PSYCHIATRY

Effects of the selective 5-HT7 receptor antagonist SB-269970 on premature responding in the five-choice serial reaction time test in rats

(2015) Agnieszka Nikiforuk et al.   BEHAVIOURAL BRAIN RESEARCH

A Methionine-Induced Animal Model of Schizophrenia: Face and Predictive Validity

(2015) Lien Wang et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

α2-Adrenoceptors in the treatment of major neuropsychiatric disorders

(2015) Salomon Z. Langer   TRENDS IN PHARMACOLOGICAL SCIENCES

A Novel Analgesic Isolated from a Traditional Chinese Medicine

(2014) Yan Zhang et al.   CURRENT BIOLOGY

The role of 5-HT7 receptor antagonism in the amelioration of MK-801-induced learning and memory deficits by the novel atypical antipsychotic drug lurasidone

(2013) Tomoko Horisawa et al.   BEHAVIOURAL BRAIN RESEARCH

A Randomized Clinical Trial of Histamine 2 Receptor Antagonism in Treatment-Resistant Schizophrenia

(2013) Katarina Meskanen et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Effects of the Selective 5-HT7 Receptor Antagonist SB-269970 and Amisulpride on Ketamine-Induced Schizophrenia-like Deficits in Rats

(2013) Agnieszka Nikiforuk et al.   PLoS One

Opposite effects of low versus high dose haloperidol treatments on spontaneous and apomorphine induced motor behavior: Evidence that at a very low dose haloperidol acts as an indirect dopamine agonist

(2012) Flávia Regina Cruz Dias et al.   BEHAVIOURAL BRAIN RESEARCH

Automated design of ligands to polypharmacological profiles

(2012) Jérémy Besnard et al.   NATURE

Ketamine-enhanced immobility in forced swim test: A possible animal model for the negative symptoms of schizophrenia

(2012) Ben A. Chindo et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Effects of the cognition impairer MK-801 on learning and memory in mice and rats

(2011) F. Josef van der Staay et al.   BEHAVIOURAL BRAIN RESEARCH

The effects of selective antagonists of serotonin 5-HT7 and 5-HT1A receptors on MK-801-induced impairment of learning and memory in the passive avoidance and Morris water maze tests in rats: Mechanistic implications for the beneficial effects of the novel atypical antipsychotic lurasidone

(2011) Tomoko Horisawa et al.   BEHAVIOURAL BRAIN RESEARCH

Animal models of schizophrenia

(2011) CA Jones et al.   BRITISH JOURNAL OF PHARMACOLOGY

Effect of PDE10A inhibitors on MK-801-induced immobility in the forced swim test

(2011) Barbara Langen et al.   PSYCHOPHARMACOLOGY

Phencyclidine-induced cognitive deficits in mice are ameliorated by subsequent subchronic administration of donepezil: Role of sigma-1 receptors

(2009) Shinsui Kunitachi et al.   BRAIN RESEARCH

Amisulpride is a potent 5-HT7 antagonist: relevance for antidepressant actions in vivo

(2009) Atheir I. Abbas et al.   PSYCHOPHARMACOLOGY

d-Serine and a glycine transporter inhibitor improve MK-801-induced cognitive deficits in a novel object recognition test in rats

(2007) Jun-ichi Karasawa et al.   BEHAVIOURAL BRAIN RESEARCH