Sexual dimorphism in activation of placental autophagy in obese women with evidence for fetal programming from a placenta-specific mouse model

Obesity and Placental Function

(2016) Alina Maloyan et al.   SEMINARS IN REPRODUCTIVE MEDICINE

AMPK: positive and negative regulation, and its role in whole-body energy homeostasis

(2015) D Grahame Hardie   CURRENT OPINION IN CELL BIOLOGY

Pregnancy distress gets under fetal skin: Maternal ambulatory assessment & sex differences in prenatal development

(2015) Colleen Doyle et al.   DEVELOPMENTAL PSYCHOBIOLOGY

Sexual dimorphism in miR-210 expression and mitochondrial dysfunction in the placenta with maternal obesity

(2015) S Muralimanoharan et al.   INTERNATIONAL JOURNAL OF OBESITY

Chronic high fat diet induces cardiac hypertrophy and fibrosis in mice

(2015) Zhi Wang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Autophagy in adipose tissue of patients with obesity and type 2 diabetes

(2015) J. Kosacka et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The placenta: a multifaceted, transient organ

(2015) G. J. Burton et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Impaired mitochondrial function in human placenta with increased maternal adiposity

(2014) James Mele et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Lipidation of Atg8: How is substrate specificity determined without a canonical E3 enzyme?

(2014) Hitoshi Nakatogawa et al.   Autophagy

Increasing Maternal Body Mass Index Is Associated with Systemic Inflammation in the Mother and the Activation of Distinct Placental Inflammatory Pathways1

(2014) Irving L.M.H. Aye et al.   BIOLOGY OF REPRODUCTION

To Be or Not to Be? How Selective Autophagy and Cell Death Govern Cell Fate

(2014) Douglas R. Green et al.   CELL

Defective Regulation of the Ubiquitin/Proteasome System in the Hypothalamus of Obese Male Mice

(2014) Leticia M. Ignacio-Souza et al.   ENDOCRINOLOGY

The interplay between mitochondria and autophagy and its role in the aging process

(2014) Alfonso Schiavi et al.   EXPERIMENTAL GERONTOLOGY

Lipid-induced NOX2 activation inhibits autophagic flux by impairing lysosomal enzyme activity

(2014) Bharat Jaishy et al.   JOURNAL OF LIPID RESEARCH

Integrative transcriptome meta-analysis reveals widespread sex-biased gene expression at the human fetal-maternal interface

(2014) S. Buckberry et al.   MOLECULAR HUMAN REPRODUCTION

Lipidation of the LC3/GABARAP family of autophagy proteins relies on a membrane-curvature-sensing domain in Atg3

(2014) Sangeeta Nath et al.   NATURE CELL BIOLOGY

Autophagy and cardiometabolic risk factors

(2014) Juan G. Juárez-Rojas et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Pharmacological correction of obesity-induced autophagy arrest using calcium channel blockers

(2014) Hwan-Woo Park et al.   Nature Communications

Role of autophagy in the progression from obesity to diabetes and in the control of energy balance

(2013) Wenying Quan et al.   ARCHIVES OF PHARMACAL RESEARCH

MTOR overactivation and interrupted autophagy flux in obese hearts

(2013) Yingmei Zhang et al.   Autophagy

Autophagy as a mechanism of antiviral defense at the maternal–fetal interface

(2013) Elizabeth Delorme-Axford et al.   Autophagy

Role of AMPK-mediated adaptive responses in human cells with mitochondrial dysfunction to oxidative stress

(2013) Shi-Bei Wu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Quality control gone wrong: mitochondria, lysosomal storage disorders and neurodegeneration

(2013) L D Osellame et al.   BRITISH JOURNAL OF PHARMACOLOGY

Differential Regulation of Distinct Vps34 Complexes by AMPK in Nutrient Stress and Autophagy

(2013) Joungmok Kim et al.   CELL

Epidermal keratinocytes form a functional skin barrier in the absence of Atg7 dependent autophagy

(2013) Heidemarie Rossiter et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop

(2013) Carmine Settembre et al.   NATURE CELL BIOLOGY

Signals from the lysosome: a control centre for cellular clearance and energy metabolism

(2013) Carmine Settembre et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Autophagy in the brain of neonates following hypoxia–ischemia shows sex- and region-specific effects

(2013) S.N. Weis et al.   NEUROSCIENCE

Regulation of autophagy by stress-responsive transcription factors

(2013) Federico Pietrocola et al.   SEMINARS IN CANCER BIOLOGY

The Role of Sex Differences in Autophagy in the Heart During Coxsackievirus B3-Induced Myocarditis

(2013) Andreas Koenig et al.   Journal of Cardiovascular Translational Research

The Hairpin-type Tail-Anchored SNARE Syntaxin 17 Targets to Autophagosomes for Fusion with Endosomes/Lysosomes

(2012) Eisuke Itakura et al.   CELL

Role of Hypothalamic Proopiomelanocortin Neuron Autophagy in the Control of Appetite and Leptin Response

(2012) Wenying Quan et al.   ENDOCRINOLOGY

Obesity results in progressive atrial structural and electrical remodeling: Implications for atrial fibrillation

(2012) Hany S. Abed et al.   HEART RHYTHM

Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy

(2012) R David Sentelle et al.   Nature Chemical Biology

Evolution of Placental Function in Mammals: The Molecular Basis of Gas and Nutrient Transfer, Hormone Secretion, and Immune Responses

(2012) Anthony M. Carter   PHYSIOLOGICAL REVIEWS

MIR-210 modulates mitochondrial respiration in placenta with preeclampsia

(2012) S. Muralimanoharan et al.   PLACENTA

Measurement of mitochondrial respiration in trophoblast culture

(2012) A. Maloyan et al.   PLACENTA

Increased Autophagy in Placentas of Intrauterine Growth-Restricted Pregnancies

(2012) Tai-Ho Hung et al.   PLoS One

The Role of Atg Proteins in Autophagosome Formation

(2011) Noboru Mizushima et al.   Annual Review of Cell and Developmental Biology

Mitochondria removal by autophagy

(2011) Ke Wang et al.   Autophagy

The role of developmental plasticity and epigenetics in human health

(2011) Peter D. Gluckman et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Autophagy in Hypothalamic AgRP Neurons Regulates Food Intake and Energy Balance

(2011) Susmita Kaushik et al.   Cell Metabolism

Defective Hypothalamic Autophagy Directs the Central Pathogenesis of Obesity via the IκB Kinase β (IKKβ)/NF-κB Pathway

(2011) Qingyuan Meng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fatty Acids Suppress Autophagic Turnover in β-Cells

(2011) Guy Las et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy Induced by Deficiency of Sphingosine-1-phosphate Phosphohydrolase 1 Is Switched to Apoptosis by Calpain-mediated Autophagy-related Gene 5 (Atg5) Cleavage

(2011) Sandrine Lépine et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Maternal inflammation, growth retardation, and preterm birth: Insights into adult cardiovascular disease

(2011) Lynette K. Rogers et al.   LIFE SCIENCES

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Autophagy in term normal human placentas

(2011) P. Signorelli et al.   PLACENTA

Sex-specific differences in placental global gene expression in pregnancies complicated by asthma

(2011) A. Osei-Kumah et al.   PLACENTA

Review: The placenta and developmental programming: Balancing fetal nutrient demands with maternal resource allocation

(2011) G.J. Burton et al.   PLACENTA

Chain length-specific properties of ceramides

(2011) Sabine Grösch et al.   PROGRESS IN LIPID RESEARCH

Role of autophagy in diabetes and mitochondria

(2010) Hye Seung Jung et al.   Annals of the New York Academy of Sciences

Intra-uterine growth restriction is associated with increased apoptosis and altered expression of proteins in the p53 pathway in villous trophoblast

(2010) Alexander E. P. Heazell et al.   APOPTOSIS

Celecoxib-induced apoptosis is enhanced by ABT-737 and by inhibition of autophagy in human colorectal cancer cells

(2010) Shengbing Huang et al.   Autophagy

Cancer Causes Cardiac Atrophy and Autophagy in a Sexually Dimorphic Manner

(2010) P. F. Cosper et al.   CANCER RESEARCH

Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance

(2010) Ling Yang et al.   Cell Metabolism

Kdo2-Lipid A, a TLR4-specific Agonist, Inducesde NovoSphingolipid Biosynthesis in RAW264.7 Macrophages, Which Is Essential for Induction of Autophagy

(2010) Kacee Sims et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-β

(2010) Polakit Teekakirikul et al.   JOURNAL OF CLINICAL INVESTIGATION

Autophagy: assays and artifacts

(2010) Sandra Barth et al.   JOURNAL OF PATHOLOGY

Autophagy: cellular and molecular mechanisms

(2010) Danielle Glick et al.   JOURNAL OF PATHOLOGY

Contrasting effects of different maternal diets on sexually dimorphic gene expression in the murine placenta

(2010) J. Mao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

(2010) D. F. Egan et al.   SCIENCE

Boys live dangerously in the womb

(2009) Johan G. Eriksson et al.   AMERICAN JOURNAL OF HUMAN BIOLOGY

Dihydroceramide intracellular increase in response to resveratrol treatment mediates autophagy in gastric cancer cells

(2009) Paola Signorelli et al.   CANCER LETTERS

p62 at the Crossroads of Autophagy, Apoptosis, and Cancer

(2009) Jorge Moscat et al.   CELL

Asthma and pregnancy: emerging evidence of epigenetic interactions in utero

(2009) Susan L Prescott et al.   Current Opinion in Allergy and Clinical Immunology

Pregnancy and Obesity

(2009) Yariv Yogev et al.   OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA

Neonates Born to Mothers With Preeclampsia Exhibit Sex-Specific Alterations in Microvascular Function

(2009) Michael J Stark et al.   PEDIATRIC RESEARCH

Review: Sex and the Human Placenta: Mediating Differential Strategies of Fetal Growth and Survival

(2009) V.L. Clifton   PLACENTA

Developmental programming: prenatal androgen excess disrupts ovarian steroid receptor balance

(2009) Hugo H Ortega et al.   REPRODUCTION

Autophagy Is Important in Islet Homeostasis and Compensatory Increase of Beta Cell Mass in Response to High-Fat Diet

(2008) Chie Ebato et al.   Cell Metabolism

Glucose Metabolism In Vivo in Four Commonly Used Inbred Mouse Strains

(2008) E. D. Berglund et al.   DIABETES

Starving Neurons Show Sex Difference in Autophagy

(2008) Lina Du et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Female Rats Fed a High-Fat Diet Were Associated with Vascular Dysfunction and Cardiac Fibrosis in the Absence of Overt Obesity and Hyperlipidemia: Therapeutic Potential of Resveratrol

(2008) M.-C. Aubin et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL

Obesity in Pregnancy Stimulates Macrophage Accumulation and Inflammation in the Placenta

(2008) J.C. Challier et al.   PLACENTA

Effect of Increasing Maternal Body Mass Index on Oxidative and Nitrative Stress in The Human Placenta

(2008) V.H.J. Roberts et al.   PLACENTA

Placental Endoplasmic Reticulum Stress and Oxidative Stress in the Pathophysiology of Unexplained Intrauterine Growth Restriction and Early Onset Preeclampsia

(2008) G.J. Burton et al.   PLACENTA

Autophagy-Related Proteins, LC3 and Beclin-1, in Placentas From Pregnancies Complicated by Preeclampsia

(2008) Soo-Young Oh et al.   Reproductive Sciences

PPAR Signaling in Placental Development and Function

(2007) Yaacov Barak et al.   PPAR Research