Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity

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(2019) Owen M. Siggs et al.   Frontiers in Immunology

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The 2017 IUIS Phenotypic Classification for Primary Immunodeficiencies

(2017) Aziz Bousfiha et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Complex Patterns of Admixture across the Indonesian Archipelago

(2017) Georgi Hudjashov et al.   MOLECULAR BIOLOGY AND EVOLUTION

The Combined Landscape of Denisovan and Neanderthal Ancestry in Present-Day Humans

(2016) Sriram Sankararaman et al.   CURRENT BIOLOGY

Archaic Hominin Admixture Facilitated Adaptation to Out-of-Africa Environments

(2016) Rachel M. Gittelman et al.   CURRENT BIOLOGY

Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne

(2016) Tycho E. T. Mevissen et al.   NATURE

A genomic history of Aboriginal Australia

(2016) Anna-Sapfo Malaspinas et al.   NATURE

Genomic insights into the peopling of the Southwest Pacific

(2016) Pontus Skoglund et al.   NATURE

The Simons Genome Diversity Project: 300 genomes from 142 diverse populations

(2016) Swapan Mallick et al.   NATURE

Excavating Neandertal and Denisovan DNA from the genomes of Melanesian individuals

(2016) B. Vernot et al.   SCIENCE

Reference genotype and exome data from an Australian Aboriginal population for health-based research

(2016) Dave Tang et al.   Scientific Data

Nuclear factor κB–inducing kinase activation as a mechanism of pancreatic β cell failure in obesity

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Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation

(2015) Ingrid E. Wertz et al.   NATURE

Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease

(2015) Qing Zhou et al.   NATURE GENETICS

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A20 controls intestinal homeostasis through cell-specific activities

(2014) Lars Vereecke et al.   Nature Communications

Haplotype Estimation Using Sequencing Reads

(2013) Olivier Delaneau et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Dimerization and Ubiquitin Mediated Recruitment of A20, a Complex Deubiquitinating Enzyme

(2013) Timothy T. Lu et al.   IMMUNITY

Helios marks strongly autoreactive CD4+T cells in two major waves of thymic deletion distinguished by induction of PD-1 or NF-κB

(2013) Stephen R. Daley et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Orchestrated Functions of Innate Leukocytes and T Cell Subsets Contribute to Humoral Immunity, Virus Control, and Recovery from Secondary Poxvirus Challenge

(2013) V. Tahiliani et al.   JOURNAL OF VIROLOGY

The complete genome sequence of a Neanderthal from the Altai Mountains

(2013) Kay Prüfer et al.   NATURE

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(2012) Janelle S. Ayres et al.   Annual Review of Immunology

Baculoviral inhibitors of apoptosis repeat containing (BIRC) proteins fine-tune TNF-induced nuclear factor κB and c-Jun N-terminal kinase signalling in mouse pancreatic beta cells

(2012) B. M. Tan et al.   DIABETOLOGIA

A20 inhibits LUBAC-mediated NF-κB activation by binding linear polyubiquitin chains via its zinc finger 7

(2012) Kelly Verhelst et al.   EMBO JOURNAL

Human lymphoma mutations reveal CARD11 as the switch between self-antigen–induced B cell death or proliferation and autoantibody production

(2012) Yogesh S. Jeelall et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Primer3—new capabilities and interfaces

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Genetic dating indicates that the Asian-Papuan admixture through Eastern Indonesia corresponds to the Austronesian expansion

(2012) S. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A High-Coverage Genome Sequence from an Archaic Denisovan Individual

(2012) M. Meyer et al.   SCIENCE

Interactions Between the Microbiota and the Immune System

(2012) L. V. Hooper et al.   SCIENCE

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Denisova Admixture and the First Modern Human Dispersals into Southeast Asia and Oceania

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Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7

(2011) Ingrid E. Wertz et al.   NATURE

Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE

(2011) Peng Qiu et al.   NATURE BIOTECHNOLOGY

Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum

(2011) S. C. Bendall et al.   SCIENCE

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Ubiquitin Binding to A20 ZnF4 Is Required for Modulation of NF-κB Signaling

(2010) Ivan Bosanac et al.   MOLECULAR CELL

Genetic history of an archaic hominin group from Denisova Cave in Siberia

(2010) David Reich et al.   NATURE

MolProbity: all-atom structure validation for macromolecular crystallography

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Phenotype and function of human T lymphocyte subsets: Consensus and issues

(2008) Victor Appay et al.   CYTOMETRY PART A

Homeostatic MyD88-dependent signals cause lethal inflamMation in the absence of A20

(2008) Emre E. Turer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Structure of the A20 OTU domain and mechanistic insights into deubiquitination

(2007) David Komander et al.   BIOCHEMICAL JOURNAL