Precision mouse models with expanded tropism for human pathogens

Zika viral infection and neutralizing human antibody response in a BLT humanized mouse model

(2018) Kimberly Schmitt et al.   VIROLOGY

HIV persistence in tissue macrophages of humanized myeloid-only mice during antiretroviral therapy

(2017) Jenna B Honeycutt et al.   NATURE MEDICINE

Animal models of respiratory syncytial virus infection

(2017) Geraldine Taylor   VACCINE

In Vivo Suppression of HIV Rebound by Didehydro-Cortistatin A, a “Block-and-Lock” Strategy for HIV-1 Treatment

(2017) Cari F. Kessing et al.   Cell Reports

Experimental study of tuberculosis: From animal models to complex cell systems and organoids

(2017) Kaori L. Fonseca et al.   PLoS Pathogens

Human Cytomegalovirus Induces Cellular and Humoral Virus-specific Immune Responses in Humanized BLT Mice

(2017) Lindsey B. Crawford et al.   Scientific Reports

The D-form of a novel heparan binding peptide decreases cytomegalovirus infection in vivo and in vitro

(2016) Elisabeth A. Pitt et al.   ANTIVIRAL RESEARCH

AXL-Mediated Productive Infection of Human Endothelial Cells by Zika VirusNovelty and Significance

(2016) Shufeng Liu et al.   CIRCULATION RESEARCH

A long-acting formulation of the integrase inhibitor raltegravir protects humanized BLT mice from repeated high-dose vaginal HIV challenges

(2016) Martina Kovarova et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

ART influences HIV persistence in the female reproductive tract and cervicovaginal secretions

(2016) Rikke Olesen et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophages sustain HIV replication in vivo independently of T cells

(2016) Jenna B. Honeycutt et al.   JOURNAL OF CLINICAL INVESTIGATION

Multiple Transcripts Encode Full-Length Human Cytomegalovirus IE1 and IE2 Proteins during Lytic Infection

(2016) Kyle C. Arend et al.   JOURNAL OF VIROLOGY

The eIF4AIII RNA helicase is a critical determinant of human cytomegalovirus replication

(2016) Ben Ziehr et al.   VIROLOGY

The South Pacific epidemic strain of Zika virus replicates efficiently in human epithelial A549 cells leading to IFN-β production and apoptosis induction

(2016) Etienne Frumence et al.   VIROLOGY

Neutralization mechanism of a highly potent antibody against Zika virus

(2016) Shuijun Zhang et al.   Nature Communications

Humanized mice for HIV and AIDS research

(2016) J Victor Garcia   Current Opinion in Virology

CD19xCD3 DART protein mediates human B-cell depletion in vivo in humanized BLT mice

(2016) Perry Tsai et al.   Molecular Therapy-Oncolytics

A mouse model for MERS coronavirus-induced acute respiratory distress syndrome

(2016) Adam S. Cockrell et al.   Nature Microbiology

Cytomegalovirus infection in transplant recipients

(2015) LS Azevedo et al.   Clinics

Biology of Zika Virus Infection in Human Skin Cells

(2015) Rodolphe Hamel et al.   JOURNAL OF VIROLOGY

Quantification of Microvascular Tortuosity during Tumor Evolution Using Acoustic Angiography

(2015) Sarah E. Shelton et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Middle East respiratory syndrome coronavirus infection: virus-host cell interactions and implications on pathogenesis

(2015) Jie Zhou et al.   Virology Journal

Humanized mouse models of human cytomegalovirus infection

(2015) Lindsey B Crawford et al.   Current Opinion in Virology

RSV-encoded NS2 promotes epithelial cell shedding and distal airway obstruction

(2014) Rachael M. Liesman et al.   JOURNAL OF CLINICAL INVESTIGATION

Respiratory syncytial virus (RSV) and its propensity for causing bronchiolitis

(2014) Raymond J Pickles et al.   JOURNAL OF PATHOLOGY

Mouse Dipeptidyl Peptidase 4 Is Not a Functional Receptor for Middle East Respiratory Syndrome Coronavirus Infection

(2014) A. S. Cockrell et al.   JOURNAL OF VIROLOGY

Diverse Specificities, Phenotypes, and Antiviral Activities of Cytomegalovirus-Specific CD8+ T Cells

(2014) S. E. Jackson et al.   JOURNAL OF VIROLOGY

Identification and HLA-Tetramer-Validation of Human CD4+ and CD8+ T Cell Responses against HCMV Proteins IE1 and IE2

(2014) Peter Braendstrup et al.   PLoS One

Hypogammaglobulinemia in BLT Humanized Mice – An Animal Model of Primary Antibody Deficiency

(2014) Francisco Martinez-Torres et al.   PLoS One

Humanized-BLT mouse model of Kaposi's sarcoma-associated herpesvirus infection

(2014) L.-X. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wild-type and innate immune-deficient mice are not susceptible to the Middle East respiratory syndrome coronavirus

(2013) C. M. Coleman et al.   JOURNAL OF GENERAL VIROLOGY

A Cluster of Virus-Encoded MicroRNAs Accelerates Acute Systemic Epstein-Barr Virus Infection but Does Not Significantly Enhance Virus-Induced Oncogenesis In Vivo

(2013) A. Wahl et al.   JOURNAL OF VIROLOGY

Cryptopatches Are Essential for the Development of Human GALT

(2013) Tomonori Nochi et al.   Cell Reports

Animal models for highly pathogenic emerging viruses

(2013) David Safronetz et al.   Current Opinion in Virology

Distribution and Compartmentalization of Human Circulating and Tissue-Resident Memory T Cell Subsets

(2012) Taheri Sathaliyawala et al.   IMMUNITY

Rapid Evolution of HIV-1 to Functional CD8+ T Cell Responses in Humanized BLT Mice

(2012) T. E. Dudek et al.   Science Translational Medicine

Human Cytomegalovirus pUS27 G Protein-Coupled Receptor Homologue Is Required for Efficient Spread by the Extracellular Route but Not for Direct Cell-to-Cell Spread

(2011) C. M. O'Connor et al.   JOURNAL OF VIROLOGY

Granulocyte-Colony Stimulating Factor Reactivates Human Cytomegalovirus in a Latently Infected Humanized Mouse Model

(2010) M. Shane Smith et al.   Cell Host & Microbe

High-resolution, high-contrast ultrasound imaging using a prototype dual-frequency transducer: In vitro and in vivo studies

(2010) Ryan Gessner et al.   IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL

Cytomegalovirus Pneumonia: Community-Acquired Pneumonia in Immunocompetent Hosts

(2010) Burke A. Cunha   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Induction of Robust Cellular and Humoral Virus-Specific Adaptive Immune Responses in Human Immunodeficiency Virus-Infected Humanized BLT Mice

(2009) D. M. Brainard et al.   JOURNAL OF VIROLOGY

Cloning and sequencing of a highly productive, endotheliotropic virus strain derived from human cytomegalovirus TB40/E

(2008) C. Sinzger et al.   JOURNAL OF GENERAL VIROLOGY

Expansion of Human Cytomegalovirus (HCMV) Immediate-Early 1-Specific CD8+ T Cells and Control of HCMV Replication after Allogeneic Stem Cell Transplantation

(2008) K. Sacre et al.   JOURNAL OF VIROLOGY