Journal
NANO TODAY
Volume 28, Issue -, Pages -Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.nantod.2019.100765
Keywords
Drug delivery; Nanosystems; Local administration; Systemic administration; Local effects
Categories
Funding
- NIH [R35 GM131728]
- Anesthesia Research Distinguished Trailblazer Award
Ask authors/readers for more resources
Many diseases and conditions affect a relatively localized area of the body. They can be treated either by direct deposition of drug in the target area, or by giving the drug systemically. Here we review nanoparticle-based approaches to achieving both. We highlight advantages and disadvantages that nanoscale solutions have for locally administered therapies, with emphasis on the former. We discuss strategies to enable systemically delivered nanoparticles to deliver their payloads to specific locations in the body, including triggering (local and remote) and targeting. Published by Elsevier Ltd.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available