Discovery of dihydroisoquinolinone derivatives as novel inhibitors of the p53–MDM2 interaction with a distinct binding mode

Title
Discovery of dihydroisoquinolinone derivatives as novel inhibitors of the p53–MDM2 interaction with a distinct binding mode
Authors
Keywords
MDM2, p53, Protein–protein interaction inhibitors
Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 25, Issue 17, Pages 3621-3625
Publisher
Elsevier BV
Online
2015-06-23
DOI
10.1016/j.bmcl.2015.06.058

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